World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
101
Citations
32251
World Ranking
1468
National Ranking
836

Medicine

D-Index
102
Citations
32777
World Ranking
7751
National Ranking
4037

Research.com Recognitions

  • 2012 - Fellow of Alfred P. Sloan Foundation

Overview

John A. Kessler is affiliated with Northwestern University in the United States and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work focuses on various subfields including Molecular Biology, Cellular and Molecular Neuroscience, Immunology, Physiology, and Developmental Neuroscience.

Their research covers several main topics of interest such as RNA Research and Splicing, Alzheimer's disease research and treatments, Bone Metabolism and Diseases, Neurogenesis and neuroplasticity mechanisms, MicroRNA in disease regulation, Epigenetics and DNA Methylation, and Neuroscience and Neuropharmacology Research.

An overview of selected recent papers includes:

  • Gene therapy for diabetic peripheral neuropathy: A randomized, placebo-controlled phase III study of VM202, a plasmid DNA encoding human hepatocyte growth factor (2021, Clinical and Translational Science)
  • PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells (2021, Molecular Cell)
  • Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice (2022, Nature Communications)
  • Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua (2021, Cell Reports)
  • Intravenous Immunomodulatory Nanoparticle Treatment for Traumatic Brain Injury (2020, Annals of Neurology)

Frequent collaborators include Ahmet Höke, Leon G. Epstein, Jennifer Graves, Johns Hopkins researchers, and Puneet Opal.

The scientist's publications are frequently found in venues such as Annals of Clinical and Translational Neurology, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Alzheimer's & Dementia, and Small.

John A. Kessler has been recognized with a Fellow of Alfred P. Sloan Foundation award in 2012.

Best Publications

  • Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers

    Gabriel A. Silva;Gabriel A. Silva;Catherine Czeisler;Krista L. Niece;Elia Beniash

  • Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells.

    Robert E Gross;Mark F Mehler;Peter C Mabie;Ziying Zang

  • Self-Assembling Nanofibers Inhibit Glial Scar Formation and Promote Axon Elongation after Spinal Cord Injury

    Vicki M. Tysseling-Mattiace;Vibhu Sahni;Krista L. Niece;Derin Birch

  • Bone morphogenetic proteins in the nervous system

    Mark F Mehler;Peter C Mabie;Damin Zhang;John A Kessler

  • Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases

    Richard K. Burt;Yvonne Loh;William Pearce;Nirat Beohar

  • Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis

    R Dermietzel;EL Hertberg;JA Kessler;DC Spray

  • Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation.

    Jayshree Samanta;John A. Kessler

  • Nerve growth factor administration protects against experimental diabetic sensory neuropathy

    Stuart C. Apfel;Joseph C. Arezzo;Michael Brownlee;Howard Federoff

  • Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype.

    Peter C. Mabie;Mark F. Mehler;John A. Kessler

  • Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy. NGF Study Group.

    S. C. Apfel;J. A. Kessler;B. T. Adornato;W. J. Litchy

  • Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment

    William A Gomes;Mark F Mehler;John A Kessler

  • Bone Morphogenetic Proteins Induce Astroglial Differentiation of Oligodendroglial–Astroglial Progenitor Cells

    P. C. Mabie;M. F. Mehler;R. Marmur;A. Papavasiliou

  • Cytokine regulation of neuronal differentiation of hippocampal progenitor cells

    Mark F. Mehler;Renato Rozental;Renato Rozental;Maryjane Dougherty;David C. Spray

  • The presence of FGF2 signaling determines whether β-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells

    Nipan Israsena;Min Hu;Weimin Fu;Lixin Kan

  • LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells.

    Michael A. Bonaguidi;Tammy McGuire;Min Hu;Lixin Kan

  • Functional Properties of Channels Formed by the Neuronal Gap Junction Protein Connexin36

    Midituru Srinivas;Renato Rozental;Renato Rozental;Takashi Kojima;Rolf Dermietzel

  • Involvement of gap junctions in tumorigenesis : transfection of tumor cells with connexin 32 cDNA retards growth in vivo

    B. Eghbali;J. A. Kessler;L. M. Reid;C. Roy

  • Noggin Expands Neural Stem Cells in the Adult Hippocampus

    Michael A. Bonaguidi;Chian Yu Peng;Tammy McGuire;Gustave Falciglia;Gustave Falciglia

  • Substance P in principal sympathetic neurons: Regulation by impulse activity

    John A. Kessler;Joshua E. Adler;Martha C. Bohn;Ira B. Black

  • Nerve growth factor prevents toxic neuropathy in mice

    Stuart C. Apfel;Richard B. Lipton;Joseph C. Arezzo;John A. Kessler

Frequent Co-Authors

Mark F. Mehler
Mark F. Mehler Albert Einstein College of Medicine
Ira B. Black
Ira B. Black Rutgers, The State University of New Jersey
Samuel I. Stupp
Samuel I. Stupp Northwestern University
David C. Spray
David C. Spray Albert Einstein College of Medicine
Shi Yuan Cheng
Shi Yuan Cheng Northwestern University
Horacio D. Espinosa
Horacio D. Espinosa Northwestern University
Ichiro Nakano
Ichiro Nakano University of Alabama at Birmingham
Rolf Dermietzel
Rolf Dermietzel Ruhr University Bochum
Joseph C. Arezzo
Joseph C. Arezzo Albert Einstein College of Medicine
Richard J. Miller
Richard J. Miller Northwestern University

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