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Jorge C. Escalante-Semerena

Jorge C. Escalante-Semerena

D-Index & Metrics

Chemistry

D-Index
62
Citations
11849
World Ranking
8967
National Ranking
2542

Biology and Biochemistry

D-Index
63
Citations
13091
World Ranking
10294
National Ranking
4485

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jorge C. Escalante-Semerena is a researcher primarily affiliated with the University of Georgia in the United States. Their work spans multiple fields, predominantly within biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology and related subfields such as rheumatology, materials chemistry, oncology, and genetics.

The researcher's publications address topics that include porphyrin metabolism and disorders, folate and B vitamins research, enzyme structure and function, peptidase inhibition and analysis, biochemical and molecular research, bacterial genetics and biotechnology, as well as Salmonella and Campylobacter epidemiology. These focus areas reflect a breadth of investigation into microbial biochemistry and molecular processes.

Publication venues frequently hosting their work include mBio, Methods in Enzymology on CD-ROM/Methods in Enzymology, Journal of Bacteriology, Molecular Microbiology, and Biochemistry. These journals highlight the interdisciplinary nature of their research, bridging microbiology and biochemical methods.

Key recent papers authored or co-authored by Jorge C. Escalante-Semerena include:

  • Small-Molecule Acetylation by GCN5-Related N-Acetyltransferases in Bacteria, 2020, Microbiology and Molecular Biology Reviews
  • Modulation of the bacterial CobB sirtuin deacylase activity by N-terminal acetylation, 2020, Proceedings of the National Academy of Sciences
  • Insights into the Relationship between Cobamide Synthase and the Cell Membrane, 2021, mBio
  • Acinetobacter baumannii Catabolizes Ethanolamine in the Absence of a Metabolosome and Converts Cobinamide into Adenosylated Cobamides, 2022, mBio
  • Localization and interaction studies of the Salmonella enterica ethanolamine ammonia-lyase (EutBC), its reactivase (EutA), and the EutT corrinoid adenosyltransferase, 2022, Molecular Microbiology

Frequent co-authors collaborating with Jorge C. Escalante-Semerena include:

  • Anastacia R. Parks
  • Victoria L. Jeter
  • Elizabeth A. Villa
  • Flavia G. Costa
  • Lahiru Malalasekara

They have been recognized by the American Association for the Advancement of Science (AAAS) as a Fellow since 2010.

Best Publications

  • A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

    Jeffrey S. Smith;Carrie Baker Brachmann;Carrie Baker Brachmann;Ivana Celic;Margaret A. Kenna;Margaret A. Kenna

  • Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine

    V. J. Starai;I. Celic;R. N. Cole;J. D. Boeke

  • The biosynthesis of adenosylcobalamin (vitamin B12)

    Martin J. Warren;Evelyne Raux;Heidi L. Schubert;Jorge C. Escalante-Semerena

  • Identification of the protein acetyltransferase (Pat) enzyme that acetylates acetyl-CoA synthetase in Salmonella enterica.

    Vincent J Starai;Jorge C Escalante-Semerena

  • The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.

    Andrew M. Gulick;Vincent J. Starai;Alexander R. Horswill;Kristen M. Homick

  • Acetyl-coenzyme A synthetase (AMP forming)

    V J Starai;J C Escalante-Semerena

  • N-Lysine Propionylation Controls the Activity of Propionyl-CoA Synthetase

    Jane Garrity;Jeffrey G. Gardner;William Hawse;Cynthia Wolberger

  • Acylation of Biomolecules in Prokaryotes: a Widespread Strategy for the Control of Biological Function and Metabolic Stress

    Kristy L. Hentchel;Jorge C. Escalante-Semerena

  • CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2.

    Allen W. Tsang;Jorge C. Escalante-Semerena

  • Salmonella typhimurium LT2 Catabolizes Propionate via the 2-Methylcitric Acid Cycle

    Alexander R. Horswill;Jorge C. Escalante-Semerena

  • Tetrahydromethanopterin, a carbon carrier in methanogenesis.

    J C Escalante-Semerena;K L Rinehart;R S Wolfe

  • Minimal Functions and Physiological Conditions Required for Growth of Salmonella enterica on Ethanolamine in the Absence of the Metabolosome

    Shaun R. Brinsmade;Tenzin Paldon;Jorge C. Escalante-Semerena

  • Construction and use of new cloning vectors for the rapid isolation of recombinant proteins from Escherichia coli.

    C. R. Rocco;K. L. Dennison;Vadim A. Klenchin;I. Rayment

  • Nε-lysine acetylation of a bacterial transcription factor inhibits Its DNA-binding activity.

    Sandy Thao;Chien Sheng Chen;Chien Sheng Chen;Heng Zhu;Jorge C. Escalante-Semerena

  • Control of Acetyl-Coenzyme A Synthetase (AcsA) Activity by Acetylation/Deacetylation without NAD+ Involvement in Bacillus subtilis

    Jeffrey G. Gardner;Frank J. Grundy;Tina M. Henkin;Jorge C. Escalante-Semerena

  • In vitro conversion of propionate to pyruvate by Salmonella enterica enzymes: 2-methylcitrate dehydratase (PrpD) and aconitase Enzymes catalyze the conversion of 2-methylcitrate to 2-methylisocitrate.

    Alexander R. Horswill;Jorge C. Escalante-Semerena

  • Characterization of the propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica: residue Lys592 is required for propionyl-AMP synthesis.

    Alexander R Horswill;Jorge C Escalante-Semerena

  • Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon.

    A R Horswill;J C Escalante-Semerena

  • cobA function is required for both de novo cobalamin biosynthesis and assimilation of exogenous corrinoids in Salmonella typhimurium.

    J. C. Escalante-Semerena;Sang-Jin Suh;J. R. Roth

  • Regulation of cobalamin biosynthetic operons in Salmonella typhimurium.

    Jorgec . Escalante-Semerena;John R. Roth

  • Studies of Propionate Toxicity in Salmonella enterica Identify 2-Methylcitrate as a Potent Inhibitor of Cell Growth

    Alexander R. Horswill;Andrea R. Dudding;Jorge C. Escalante-Semerena

Frequent Co-Authors

Ivan Rayment
Ivan Rayment University of Wisconsin–Madison
Alexander R. Horswill
Alexander R. Horswill University of Colorado Anschutz Medical Campus
Thomas C. Brunold
Thomas C. Brunold University of Wisconsin–Madison
Martin J. Warren
Martin J. Warren University of Kent
Cynthia Wolberger
Cynthia Wolberger Johns Hopkins University School of Medicine
Jef D. Boeke
Jef D. Boeke New York University
Joshua Fierer
Joshua Fierer University of California, San Diego
James B. Thoden
James B. Thoden University of Wisconsin–Madison
John R. Roth
John R. Roth University of California, Davis
Hazel M. Holden
Hazel M. Holden University of Wisconsin–Madison

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