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Immunology

D-Index
63
Citations
11802
World Ranking
3067
National Ranking
1436

Overview

Manuel V. Borca is affiliated with the United States Department of Agriculture in the United States. Their research spans multiple aspects of animal diseases, particularly focusing on viral infections and epidemiology in agricultural and biological sciences.

The scientist's main fields of study include Agricultural and Biological Sciences and Medicine. Within these, Borca's subfields of interest cover Agronomy and Crop Science, Ecology, Evolution, Behavior and Systematics, Cardiology and Cardiovascular Medicine, Infectious Diseases, and Molecular Biology.

Borca's research addresses key topics such as Animal Disease Management and Epidemiology, Vector-Borne Animal Diseases, Viral Infections and Immunology Research, Viral Gastroenteritis Research and Epidemiology, Viral Infectious Diseases and Gene Expression in Insects, Animal Virus Infections Studies, and T-cell and Retrovirus Studies.

Notable recent papers authored or coauthored by Borca include:

  • Development of a Highly Effective African Swine Fever Virus Vaccine by Deletion of the I177L Gene Results in Sterile Immunity against the Current Epidemic Eurasia Strain (2020, Journal of Virology)
  • Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine (2020, Scientific Reports)

Other highly cited papers in related collaborations include:

  • African swine fever virus vaccine candidate ASFV-G-ΔI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain (2021, Transboundary and Emerging Diseases)
  • Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic (2020, Frontiers in Microbiology)
  • Deletion of the A137R Gene from the Pandemic Strain of African Swine Fever Virus Attenuates the Strain and Offers Protection against the Virulent Pandemic Virus (2021, Journal of Virology)

Frequent coauthors collaborating with Borca include:

  • Douglas P. Gladue
  • Elizabeth Ramírez-Medina
  • Lauro Velázquez-Salinas
  • Ayushi Rai
  • Ediane Silva

Borca often publishes in journals such as Viruses, Journal of Virology, Microbiology Resource Announcements, Pathogens, and Scientific Reports.

Best Publications

  • The Role of Interleukin 6 During Viral Infections.

    Lauro Velazquez-Salinas;Antonio Verdugo-Rodriguez;Luis L. Rodriguez;Manuel V. Borca

  • ICTV Virus Taxonomy Profile: Asfarviridae.

    Covadonga Alonso;Manuel Borca;Linda Dixon;Yolanda Revilla

  • African Swine Fever Virus Georgia Isolate Harboring Deletions of MGF360 and MGF505 Genes Is Attenuated in Swine and Confers Protection against Challenge with Virulent Parental Virus

    Vivian O'Donnell;Vivian O'Donnell;Lauren G. Holinka;Douglas P. Gladue;Douglas P. Gladue;Brenton Sanford

  • Development of a Highly Effective African Swine Fever Virus Vaccine by Deletion of the I177L Gene Results in Sterile Immunity against the Current Epidemic Eurasia Strain.

    Manuel V. Borca;Elizabeth Ramirez-Medina;Elizabeth Ramirez-Medina;Ediane Silva;Ediane Silva;Elizabeth Vuono;Elizabeth Vuono

  • Deletion of a CD2-Like Gene, 8-DR, from African Swine Fever Virus Affects Viral Infection in Domestic Swine

    M. V. Borca;C. Carrillo;L. Zsak;W. W. Laegreid

  • Preclinical Diagnosis of African Swine Fever in Contact-Exposed Swine by a Real-Time PCR Assay

    L. Zsak;M. V. Borca;G. R. Risatti;A. Zsak

  • Passively Transferred African Swine Fever Virus Antibodies Protect Swine against Lethal Infection

    D V Onisk;M V Borca;G Kutish;E Kramer

  • African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge

    Vivian O'Donnell;Vivian O'Donnell;Lauren G. Holinka;Peter W. Krug;Douglas P. Gladue;Douglas P. Gladue

  • Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous Challenge.

    Vivian O'Donnell;Vivian O'Donnell;Guillermo R. Risatti;Lauren G. Holinka;Peter W. Krug

  • The E2 glycoprotein of classical swine fever virus is a virulence determinant in swine

    G. R. Risatti;M. V. Borca;G. F. Kutish;Z. Lu

  • The Progressive Adaptation of a Georgian Isolate of African Swine Fever Virus to Vero Cells Leads to a Gradual Attenuation of Virulence in Swine Corresponding to Major Modifications of the Viral Genome

    Peter W. Krug;Lauren G. Holinka;Vivian O'Donnell;Bo Reese

  • African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against parental virus challenge.

    Vivian O’Donnell;Lauren G. Holinka;Brenton Sanford;Peter W. Krug

  • African swine fever virus vaccine candidate ASFV-G-ΔI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain.

    Xuan Hanh Tran;Thi Thu Phuong Le;Quang Huy Nguyen;Thanh Thuy Do

  • Foot-and-mouth disease virus utilizes an autophagic pathway during viral replication.

    Vivian O'Donnell;Vivian O'Donnell;Juan M. Pacheco;Michael LaRocco;Tom Burrage

  • An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption.

    M.V. Borca;G.F. Kutish;C.L. Afonso;P. Irusta

  • Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic

    Lauro Velazquez-Salinas;Selene Zarate;Samantha Eberl;Douglas P Gladue

  • Deletion of the A137R Gene from the Pandemic Strain of African Swine Fever Virus Attenuates the Strain and Offers Protection against the Virulent Pandemic Virus.

    Douglas P Gladue;Elizabeth Ramirez-Medina;Elizabeth Vuono;Elizabeth Vuono;Ediane Silva

  • N-linked glycosylation status of classical swine fever virus strain Brescia E2 glycoprotein influences virulence in swine.

    G. R. Risatti;L. G. Holinka;I. Fernandez Sainz;C. Carrillo

  • Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen.

    María J. Dus Santos;Consuelo Carrillo;Fernando Ardila;Raúl D. Ríos

  • Foot-and-Mouth Disease Virus Nonstructural Protein 2C Interacts with Beclin1, Modulating Virus Replication

    D. P. Gladue;V. O'Donnell;R. Baker-Branstetter;L. G. Holinka

  • Identification of a novel virulence determinant within the E2 structural glycoprotein of classical swine fever virus.

    G.R. Risatti;L.G. Holinka;C. Carrillo;G.F. Kutish

  • Rapid detection of classical swine fever virus by a portable real-time reverse transcriptase PCR assay.

    G. R. Risatti;J. D. Callahan;W. M. Nelson;M. V. Borca

Frequent Co-Authors

Zhiqiang Lu
Zhiqiang Lu United States Department of Agriculture
Luis L. Rodriguez
Luis L. Rodriguez United States Department of Agriculture
Daniel L. Rock
Daniel L. Rock University of Illinois at Urbana-Champaign
Gerald F. Kutish
Gerald F. Kutish University of Connecticut
Claudio L. Afonso
Claudio L. Afonso United States Department of Agriculture
Covadonga Alonso
Covadonga Alonso Spanish National Research Council
Jens H. Kuhn
Jens H. Kuhn National Institutes of Health
Francisco Sobrino
Francisco Sobrino Spanish National Research Council
Juan-Carlos Saiz
Juan-Carlos Saiz Autonomous University of Madrid
Andres M Perez
Andres M Perez University of Minnesota

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