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D-Index & Metrics

Biology and Biochemistry

D-Index
42
Citations
10897
World Ranking
19449
National Ranking
7932

Overview

Susan Smith is affiliated with New York University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scholarly work spans several specialized subfields including molecular biology, physiology, oncology, immunology, and aging.

The main topics addressed in their research include:

  • Telomeres, Telomerase, and Senescence
  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • Ubiquitin and proteasome pathways
  • Mechanisms of cancer metastasis
  • Genetics, Aging, and Longevity in Model Organisms
  • CRISPR and Genetic Engineering

Notable recent papers authored or coauthored by Susan Smith are:

  • "ADP-ribosyltransferases, an update on function and nomenclature," 2021, published in FEBS Journal
  • "Nuclear PARPs and genome integrity," 2020, published in Genes & Development
  • "Persistent telomere cohesion protects aged cells from premature senescence," 2020, published in Nature Communications
  • "Multiple E3 ligases control tankyrase stability and function," 2023, published in Nature Communications
  • "A multisite study of nurse-reported perceptions and practice of ABCDEF bundle components," 2020, published in Intensive and Critical Care Nursing

Their frequent coauthors include:

  • Kameron Azarm
  • Jérôme Perrard
  • Amit Bhardwaj
  • Samantha Sze
  • Katherine Ring

Smith's work appears regularly in various publication venues with multiple articles published in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Communications
  • Critical Care Medicine
  • Journal of Investigative Dermatology

The array of research publications and varied coauthorship reflect a multidisciplinary approach primarily centered on molecular mechanisms relevant to aging, cancer biology, and genome integrity. Their research contributes to advancing understanding of cellular processes such as DNA repair, protein regulation via ubiquitin pathways, and the impact of telomere dynamics on cellular aging and senescence.

Best Publications

  • Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro

    Susan Smith;Bruce Stillman

  • Tankyrase promotes telomere elongation in human cells.

    Susan Smith;Titia de Lange

  • TRF1 is a dimer and bends telomeric DNA

    Alessandro Bianchi;Susan Smith;Laura Chong;Peter Elias

  • The world according to PARP

    Susan Smith

  • Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres.

    Brandoch D Cook;Jasmin N Dynek;William G Chang;Grigoriy Shostak

  • A Dynamic Molecular Link between the Telomere Length Regulator TRF1 and the Chromosome End Protector TRF2

    Benjamin R. Houghtaling;Leanora Cuttonaro;William Chang;Susan Smith

  • Stepwise assembly of chromatin during DNA replication in vitro.

    Smith S;Stillman B

  • Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

    Christian Boehler;Laurent R. Gauthier;Oliver Mortusewicz;Denis S. Biard

  • Tankyrase function at telomeres, spindle poles, and beyond

    Susan J. Hsiao;Susan Smith

  • TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

    William Chang;Jasmin N. Dynek;Susan Smith

  • Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes.

    S. Smith;T. de Lange

  • Ataxia telangiectasia mutated activation by transcription‐ and topoisomerase I‐induced DNA double‐strand breaks

    Olivier Sordet;Christophe E Redon;Josée Guirouilh‐Barbat;Susan Smith

  • Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells

    Silvia Canudas;Susan Smith

  • ADP-ribosyltransferases, an update on function and nomenclature

    Bernhard Lüscher;Ivan Ahel;Matthias Altmeyer;Alan Ashworth

  • The Telomeric Poly(ADP-ribose) Polymerase, Tankyrase 1, Contains Multiple Binding Sites for Telomeric Repeat Binding Factor 1 (TRF1) and a Novel Acceptor, 182-kDa Tankyrase-binding Protein (TAB182)

    Hiroyuki Seimiya;Susan Smith

  • DNA sequence of the rat growth hormone gene: location of the 5' terminus of the growth hormone mRNA and identification of an internal transposon-like element.

    Guy S. Page;Susan Smith;Howard M. Goodman

  • NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.

    William Chang;Jasmin N. Dynek;Susan Smith

  • Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.

    Y. Jeffrey Chiang;Susan J. Hsiao;Dena Yver;Samuel W. Cushman

  • The first membrane spanning region of the lamin B receptor is sufficient for sorting to the inner nuclear membrane.

    Susan Smith;Gfinter Blobel

  • TRF1, a mammalian telomeric protein.

    Susan Smith;Titia de Lange

Frequent Co-Authors

Titia de Lange
Titia de Lange Rockefeller University
Patricia L. Opresko
Patricia L. Opresko University of Pittsburgh
David S. Hong
David S. Hong The University of Texas MD Anderson Cancer Center
Bruce Stillman
Bruce Stillman Cold Spring Harbor Laboratory
Jacob Piehler
Jacob Piehler Osnabrück University
Françoise Dantzer
Françoise Dantzer University of Strasbourg
Takashi Tsuruo
Takashi Tsuruo Japanese Foundation For Cancer Research
Keunchil Park
Keunchil Park The University of Texas MD Anderson Cancer Center
Yoon-Koo Kang
Yoon-Koo Kang Asan Medical Center
Zhao-Qi Wang
Zhao-Qi Wang Friedrich Schiller University Jena

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