World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
130
Citations
78874
World Ranking
273
National Ranking
37

Overview

Nigel J. Cairns is affiliated with the University of Exeter in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in related subfields including Physiology, Neurology, Psychiatry and Mental Health, Molecular Biology, and Cognitive Neuroscience.

The scientist's main research topics cover a range of neurological conditions and methodologies, particularly:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Parkinson's Disease Mechanisms and Treatments
  • Bioinformatics and Genomic Networks
  • Functional Brain Connectivity Studies
  • Genetic Associations and Epidemiology
  • Neurological diseases and metabolism

Nigel J. Cairns has published extensively, with frequently appearing venues including:

  • Scientific Reports
  • Nature Communications
  • JAMA Neurology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuropathology & Experimental Neurology

Notable recent publications include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture, 2021, Nature Genetics
  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease, 2020, Nature Communications
  • Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease, 2021, JAMA Neurology
  • The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy, 2021, Journal of Neuropathology & Experimental Neurology

Frequent co-authors collaborating with Nigel J. Cairns include:

  • John C. Morris
  • Michael Donohue
  • Laurel Beckett
  • Bret Borowski
  • Karen Crawford

Best Publications

  • Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

    Randall J. Bateman;Chengjie Xiong;Tammie L.S. Benzinger;Anne M. Fagan

  • National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

    Bradley T. Hyman;Creighton H. Phelps;Thomas G. Beach;Eileen H. Bigio

  • National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

    Thomas J. Montine;Creighton H. Phelps;Thomas G. Beach;Eileen H. Bigio

  • Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

    Peter T Nelson;Irina Alafuzoff;Eileen H Bigio;Constantin Bouras

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Primary age-related tauopathy (PART): a common pathology associated with human aging

    John F. Crary;John Q. Trojanowski;Julie A. Schneider;Jose F. Abisambra

  • The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

    Michael W. Weiner;Michael W. Weiner;Dallas P. Veitch;Paul S. Aisen;Laurel A Beckett

  • Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

    Nigel J. Cairns;Eileen H. Bigio;Ian R A Mackenzie;Manuela Neumann

  • Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

    M G Spillantini;R A Crowther;R Jakes;N J Cairns

  • Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations

    Ian R.A. Mackenzie;Eileen H. Bigio;Paul G. Ince;Felix Geser

  • TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.

    Tyler K. Ulland;Wilbur M. Song;Stanley Ching Cheng Huang;Jason D. Ulrich

  • Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

    Ian R. A. Mackenzie;Manuela Neumann;Eileen H. Bigio;Nigel J. Cairns

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy

    Ann C. McKee;Nigel J. Cairns;Dennis W. Dickson;Rebecca D. Folkerth

  • Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

    Matthew R Brier;Brian Gordon;Karl Friedrichsen;John E McCarthy

  • TDP-43 A315T mutation in familial motor neuron disease.

    Michael A. Gitcho;Robert H. Baloh;Sumi Chakraverty;Kevin Mayo

  • TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

    Iga Wegorzewska;Shaughn Bell;Nigel J. Cairns;Timothy M. Miller

  • Proteopathic tau seeding predicts tauopathy in vivo

    Brandon B. Holmes;Jennifer L. Furman;Thomas E. Mahan;Tritia R. Yamasaki

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease

    Leonidas Lyras;Nigel J. Cairns;Andrew Jenner;Peter Jenner

  • Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study

    Stephanie J.B. Vos;Chengjie Xiong;Pieter Jelle Visser;Pieter Jelle Visser;Mateusz S. Jasielec

Frequent Co-Authors

John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Robert H. Perry
Robert H. Perry Newcastle University
Carol Brayne
Carol Brayne University of Cambridge
Stephen J. Moss
Stephen J. Moss Tufts University
John C. Morris
John C. Morris Washington University in St. Louis
Virginia M.-Y. Lee
Virginia M.-Y. Lee University of Pennsylvania
Peter Heutink
Peter Heutink German Center for Neurodegenerative Diseases
Nancy L. Pedersen
Nancy L. Pedersen Karolinska Institute
Anthony J. Brookes
Anthony J. Brookes University of Leicester
Kaj Blennow
Kaj Blennow University of Gothenburg

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Neuroscience can open doors to complementary online degrees that broaden your career options in healthcare, research, and counseling. A popular entry route involves psychology degrees that are available at the undergraduate and graduate levels. These programs give students a solid foundation in human behavior and mental processes, which are directly connected to neuroscience.

For those interested in advanced clinical careers with a social impact, consider a 1 year online master's in social work. This degree equips graduates with critical skills for community settings and mental health agencies.

Individuals seeking specialized roles, such as clinical psychologists, may benefit from online psy d programs that emphasize evidence-based psychological practices. In addition, careers in family therapy and relationship counseling can be accelerated through mft online programs, designed to be flexible for working professionals.

Each pathway offers unique advantages and can be tailored to fit individual interests, whether in clinical practice, research, or social service. Carefully compare program length, cost, and admission requirements to find the right fit for your neuroscience-related goals.

Best Scientists Citing Nigel J. Cairns

Trending Scientists

Recently Published Articles