World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
17038
World Ranking
2831
National Ranking
1355

Overview

Dirk Hockemeyer is affiliated with the University of California, Berkeley in the United States. Their research is situated primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, encompassing numerous studies in Molecular Biology, Physiology, Infectious Diseases, Genetics, and Neurology.

The main topics of Dirk Hockemeyer's scientific work include CRISPR and Genetic Engineering, Telomeres, Telomerase, and Senescence, Genomics and Chromatin Dynamics, Pluripotent Stem Cells Research, Advanced biosensing and bioanalysis techniques, DNA Repair Mechanisms, and SARS-CoV-2 detection and testing.

Dirk Hockemeyer's recent papers reflect active contributions to cutting-edge research in genetics and stem cell biology. Among these are:

  • Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells (2020, Cell Reports)
  • TERT promoter mutations and telomeres during tumorigenesis (2020, Current Opinion in Genetics & Development)
  • Highly efficient generation of isogenic pluripotent stem cell models using prime editing (2022, eLife)
  • Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution (2020, Communications Biology)
  • TINF2 is a haploinsufficient tumor suppressor that limits telomere length (2020, eLife)

Frequent co-authors contributing alongside Dirk Hockemeyer include Hanqin Li, Helen S. Bateup, Oriol Busquets, Khaja Mohieddin Syed, and Donald C. Rio.

The scientist's work has appeared in multiple publication venues, notably bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Cell Reports, and eLife, indicating a diverse publication portfolio across preprint servers, open-access platforms, and peer-reviewed journals.

Best Publications

  • Parkinson’s Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

    Frank Soldner;Dirk Hockemeyer;Caroline Beard;Qing Gao

  • Genetic engineering of human pluripotent cells using TALE nucleases

    Dirk Hockemeyer;Haoyi Wang;Samira Kiani;Christine S Lai

  • Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

    Dirk Hockemeyer;Frank Soldner;Caroline Beard;Qing Gao

  • Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

    Agnel Sfeir;Settapong T. Kosiyatrakul;Dirk Hockemeyer;Sheila L. MacRae

  • Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations

    Frank Soldner;Josée Laganière;Albert W. Cheng;Dirk Hockemeyer

  • Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression

    Zhigao Wang;Da Zhi Wang;Da Zhi Wang;Dirk Hockemeyer;John McAnally

  • POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

    Jeffrey Zheng-Sheng Ye;Dirk Hockemeyer;Andrew N. Krutchinsky;Diego Loayza

  • Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

    Da Zhi Wang;Shijie Li;Dirk Hockemeyer;Lillian Sutherland

  • Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

    Gunnar Hargus;Oliver Cooper;Michela Deleidi;Adam Levy

  • Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms

    Tsung-Li Liu;Srigokul Upadhyayula;Daniel E. Milkie;Ved Vati Singh

  • Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

    Matthew G. Guenther;Garrett M. Frampton;Frank Soldner;Dirk Hockemeyer

  • Recent Expansion of the Telomeric Complex in Rodents: Two Distinct POT1 Proteins Protect Mouse Telomeres

    Dirk Hockemeyer;Jan-Peter Daniels;Hiroyuki Takai;Titia de Lange

  • Induced Pluripotent Stem Cells Meet Genome Editing

    Dirk Hockemeyer;Rudolf Jaenisch

  • A drug-inducible system for direct reprogramming of human somatic cells to pluripotency.

    Dirk Hockemeyer;Frank Soldner;Elizabeth G. Cook;Qing Gao

  • POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

    Dirk Hockemeyer;Agnel J Sfeir;Jerry W Shay;Woodring E Wright

  • Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

    Russell C. DeKelver;Vivian M. Choi;Erica A. Moehle;David E. Paschon

  • Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons.

    Yun Li;Haoyi Wang;Julien Muffat;Albert W. Cheng

  • Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.

    Kunitoshi Chiba;Franziska K. Lorbeer;A. Hunter Shain;David T. McSwiggen

  • A multimodal cell census and atlas of the mammalian primary motor cortex

    Ricky Adkins;Andrew Aldridge;Shona Allen

  • Genetic engineering of human ES and iPS cells using TALE nucleases

    Dirk Hockemeyer;Haoyi Wang;Samira Kiani;Christine S. Lai

Frequent Co-Authors

Fyodor D. Urnov
Fyodor D. Urnov University of California, Berkeley
Titia de Lange
Titia de Lange Rockefeller University
Jennifer A. Doudna
Jennifer A. Doudna University of California, Berkeley
Philip D. Gregory
Philip D. Gregory Sangamo BioSciences (United States)
Edward J. Rebar
Edward J. Rebar Sangamo BioSciences (United States)
Kathleen Collins
Kathleen Collins University of California, Berkeley
David G. Drubin
David G. Drubin University of California, Berkeley
John Ngai
John Ngai University of California, Berkeley
Lei Zhang
Lei Zhang Sangamo BioSciences (United States)

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