World's Best Scientists 2026 revealed!
Haojie Huang

Haojie Huang

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
17132
World Ranking
6689
National Ranking
3109

Overview

Haojie Huang is affiliated with the Mayo Clinic in the United States and has an extensive research portfolio primarily focused on medicine and biochemistry, genetics, and molecular biology. Their publications reveal a strong emphasis on molecular biology, pulmonary and respiratory medicine, oncology, cancer research, and infectious diseases as subfields of study.

The scientist has contributed significantly to topics including prostate cancer treatment and research, ubiquitin and proteasome pathways, protein degradation and inhibitors, epigenetics and DNA methylation, RNA modifications and cancer, pancreatic and hepatic oncology research, as well as HIV/AIDS research and interventions.

Haojie Huang's recent papers include:

  • Targeting signaling pathways in prostate cancer: mechanisms and clinical trials, 2022, Signal Transduction and Targeted Therapy
  • Comparison of the Indicators of Psychological Stress in the Population of Hubei Province and Non-Endemic Provinces in China During Two Weeks During the Coronavirus Disease 2019 (COVID-19) Outbreak in February 2020, 2020, Medical Science Monitor
  • NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications, 2021, Chemical Society Reviews
  • Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma, 2021, Nature Communications
  • An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer, 2021, Nature Cell Biology

Frequent co-authors of Huang include Liguo Wang, Yuqian Yan, Yunqian Pan, Dejie Wang, and Donglin Ding. These collaborations indicate a network of researchers contributing to intersecting fields related to cancer biology, molecular pathways, and disease mechanisms.

The venues where Haojie Huang has most frequently published are:

  • Cancer Research
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Advanced Science

The body of work reflects numerous contributions to understanding molecular mechanisms underlying cancer, treatment resistance, and protein-related processes at the cellular level.

Best Publications

  • Androgen Receptor Signaling in Androgen-Refractory Prostate Cancer

    Michael E. Grossmann;Haojie Huang;Donald J. Tindall

  • CrossMap: a versatile tool for coordinate conversion between genome assemblies

    Hao Zhao;Zhifu Sun;Jing Wang;Haojie Huang

  • Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation.

    Haojie Huang;Kevin M. Regan;Fang Wang;Diping Wang

  • Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells.

    Ofelia L. Zegarra-Moro;Lucy J. Schmidt;Haojie Huang;Donald J. Tindall

  • CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

    Haojie Huang;Kevin M. Regan;Zhenkun Lou;Junjie Chen

  • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state.

    Horacio Murillo;Haojie Huang;Lucy J. Schmidt;David I. Smith

  • Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2

    Shuai Chen;Laura R. Bohrer;Aswathy N. Rai;Yunqian Pan

  • An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

    Jaroslaw Daniluk;Yan Liu;Defeng Deng;Jun Chu

  • Hexokinase 2-Mediated Warburg Effect Is Required for PTEN- and p53-Deficiency-Driven Prostate Cancer Growth

    Lei Wang;Hua Xiong;Fengxia Wu;Yingjie Zhang

  • Intrinsic BET inhibitor resistance in SPOP -mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation

    Pingzhao Zhang;Dejie Wang;Yu Zhao;Shancheng Ren

  • Activation of Nuclear Factor-κB in Acinar Cells Increases the Severity of Pancreatitis in Mice

    Haojie Huang;Haojie Huang;Yan Liu;Jaroslaw Daniluk;Jaroslaw Daniluk;Sebastian Gaiser

  • Regulation of FOXO protein stability via ubiquitination and proteasome degradation.

    Haojie Huang;Donald J. Tindall

  • PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression.

    Haojie Huang;John C. Cheville;Yunqian Pan;Patrick C. Roche

  • Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants.

    Jian An;Chenji Wang;Yibin Deng;Long Yu

  • p300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6.

    Jose D. Debes;Lucy J. Schmidt;Haojie Huang;Donald J. Tindall

  • A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.

    Bincy Philip;Christina Lynn Roland;Jaroslaw Daniluk;Yan Liu

  • Inhibition of the Androgen Receptor as a Novel Mechanism of Taxol Chemotherapy in Prostate Cancer

    Lu Gan;Shuai Chen;Yuwei Wang;Akira Watahiki

  • Measure transcript integrity using RNA-seq data

    Liguo Wang;Jinfu Nie;Hugues Sicotte;Ying Li

  • Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression.

    Xin Jin;Xin Jin;Donglin Ding;Yuqian Yan;Hui Li

  • FOXO1 Inhibits Runx2 Transcriptional Activity and Prostate Cancer Cell Migration and Invasion

    Haijun Zhang;Yunqian Pan;Yunqian Pan;Li Zheng;Chungyoul Choe

Frequent Co-Authors

david i smith
david i smith Mayo Clinic
Long Yu
Long Yu Fudan University
Funda Meric-Bernstam
Funda Meric-Bernstam The University of Texas MD Anderson Cancer Center
Filip Janku
Filip Janku The University of Texas MD Anderson Cancer Center
Yuzhuo Wang
Yuzhuo Wang University of British Columbia
David S. Hong
David S. Hong The University of Texas MD Anderson Cancer Center
Liewei Wang
Liewei Wang Mayo Clinic
Housheng Hansen He
Housheng Hansen He University of Toronto

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry in the USA can open doors to multiple dynamic career paths. Students interested in the health sciences or human performance may benefit from emerging online degree options that offer flexibility and specialized training.

For those drawn to fitness and athletic health, a sports science degree online can deepen knowledge of physiology, nutrition, and exercise programming. Similarly, pursuing an accelerated kinesiology degree online helps students fast-track skills in movement science and rehabilitation.

Biology graduates aiming for advanced careers in healthcare may consider post-master’s nursing pathways. Options include the fastest post master's pmhnp programs for psychiatric-mental health, or enrolling in the shortest online nurse practitioner program to qualify as a family nurse practitioner.

These online degrees can extend your expertise beyond conventional biology roles, equipping you for careers in clinical practice, sport, wellness, and healthcare leadership—all while offering the flexibility needed to balance study with real-world experience.

Best Scientists Citing Haojie Huang

Trending Scientists