World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Medicine
USA
2023

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Best Scientists

D-Index
181
Citations
153268
World Ranking
590
National Ranking
374

Medicine

D-Index
185
Citations
162302
World Ranking
305
National Ranking
196

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Medicine in United States Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Howard I. Scher is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with a significant emphasis on oncology and cancer research.

The scientist has contributed extensively to the fields of pulmonary and respiratory medicine, radiology, nuclear medicine, and imaging, as well as molecular biology. Their main areas of study can be grouped into the following categories:

  • Prostate Cancer Treatment and Research
  • Cancer Genomics and Diagnostics
  • Radiopharmaceutical Chemistry and Applications
  • Cancer, Lipids, and Metabolism
  • Prostate Cancer Diagnosis and Treatment
  • PARP Inhibition in Cancer Therapy
  • Cancer Immunotherapy and Biomarkers

Howard I. Scher has published numerous papers, with frequent publications in prominent journals such as the Journal of Clinical Oncology, European Urology, Cancer Research, Clinical Cancer Research, and The Prostate.

Recent notable papers include:

  • "Cancer therapy shapes the fitness landscape of clonal hematopoiesis," 2020, Nature Genetics
  • "Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019," 2020, European Urology
  • "Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets," 2022, Science
  • "Oncogenic Genomic Alterations, Clinical Phenotypes, and Outcomes in Metastatic Castration-Sensitive Prostate Cancer," 2020, Clinical Cancer Research
  • "Overall survival with circulating tumor DNA-guided therapy in advanced non-small-cell lung cancer," 2022, Nature Medicine

The scientist frequently collaborates with other researchers including Michael J. Morris, Wassim Abida, Dana E. Rathkopf, Ethan Barnett, and Susan F. Slovin, each representing significant coauthor relationships across multiple published works.

Howard I. Scher has been recognized as a Member of the Association of American Physicians, reflecting an established standing in the medical research community.

Best Publications

  • Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy

    Howard I. Scher;Karim Fizazi;Fred Saad;Mary-Ellen Taplin

  • Abiraterone and Increased Survival in Metastatic Prostate Cancer

    Johann S. de Bono;Christopher J. Logothetis;Arturo Molina;Karim Fizazi

  • Tumor mutational load predicts survival after immunotherapy across multiple cancer types.

    Robert M Samstein;Chung-Han Lee;Chung-Han Lee;Alexander N Shoushtari;Alexander N Shoushtari;Matthew D Hellmann;Matthew D Hellmann

  • Integrative genomic profiling of human prostate cancer

    Barry S. Taylor;Nikolaus Schultz;Haley Hieronymus;Anuradha Gopalan

  • Integrative clinical genomics of advanced prostate cancer

    Dan Robinson;Eliezer M. Van Allen;Eliezer M. Van Allen;Yi Mi Wu;Nikolaus Schultz

  • Enzalutamide in Metastatic Prostate Cancer before Chemotherapy

    Tomasz M Beer;Andrew J Armstrong;Dana E Rathkopf;Yohann Loriot

  • Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

    Charles J. Ryan;Matthew R. Smith;Johann S. De Bono;Arturo Molina

  • Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

    Ahmet Zehir;Ryma Benayed;Ronak H Shah;Aijazuddin Syed

  • Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

    Chris Tran;Samedy Ouk;Nicola J. Clegg;Yu Chen

  • Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

    Johann S. de Bono;Howard I. Scher;R. Bruce Montgomery;Christopher Parker

  • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

    Zhenbang Chen;Lloyd C. Trotman;David Shaffer;Hui Kuan Lin

  • Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.

    Ethan Basch;Allison M. Deal;Mark G. Kris;Howard I. Scher

  • The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress

    R.K. Portenoy;H.T. Thaler;A.B. Kornblith;J. McCarthy Lepore

  • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.

    Howard I. Scher;Susan Halabi;Ian Tannock;Michael Morris

  • Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Routine Cancer Treatment

    Ethan Martin Basch;Allison M. Deal;Amylou C. Dueck;Howard I. Scher

  • Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial

    Eugene D. Kwon;Charles G. Drake;Howard I. Scher;Karim Fizazi

  • Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

    Colin C. Pritchard;Joaquin Mateo;Michael F. Walsh;Navonil De Sarkar

  • Biology of Progressive, Castration-Resistant Prostate Cancer: Directed Therapies Targeting the Androgen-Receptor Signaling Axis

    Howard I. Scher;Charles L. Sawyers

  • Organoid cultures derived from patients with advanced prostate cancer

    Dong Gao;Ian Vela;Andrea Sboner;Phillip J Iaquinta

  • Rapid screening for psychologic distress in men with prostate carcinoma: a pilot study.

    Andrew J. Roth;Alice B. Kornblith;Laure Batel-Copel;Elizabeth Peabody

Frequent Co-Authors

Michael J. Morris
Michael J. Morris Memorial Sloan Kettering Cancer Center
Johann S. de Bono
Johann S. de Bono Institute of Cancer Research
Karim Fizazi
Karim Fizazi University of Paris-Saclay
Steven M. Larson
Steven M. Larson Memorial Sloan Kettering Cancer Center
Cora N. Sternberg
Cora N. Sternberg Cornell University
Glenn Heller
Glenn Heller Memorial Sloan Kettering Cancer Center
Arturo Molina
Arturo Molina Sutro Biopharma
Victor E. Reuter
Victor E. Reuter Memorial Sloan Kettering Cancer Center
Charles L. Sawyers
Charles L. Sawyers Memorial Sloan Kettering Cancer Center
David B. Solit
David B. Solit Memorial Sloan Kettering Cancer Center

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