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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9517
World Ranking
16225
National Ranking
1282

Overview

R. Craig MacLean is affiliated with the University of Oxford in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on subfields such as Molecular Medicine, Genetics, Molecular Biology, Ecology, and Endocrinology.

MacLean's work emphasizes several key topics within microbial and molecular biology research. These include:

  • Antibiotic Resistance in Bacteria
  • Evolution and Genetic Dynamics
  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • Vibrio bacteria research studies
  • Genomics and Phylogenetic Studies
  • Antibiotics Pharmacokinetics and Efficacy

The scientist has contributed notably to a variety of recent publications, among which the following are highlighted:

  • "Beyond horizontal gene transfer: the role of plasmids in bacterial evolution," 2021, Nature Reviews Microbiology
  • "Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates," 2020, Nature Communications
  • "CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa," 2020, The ISME Journal
  • "Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells," 2020, Proceedings of the National Academy of Sciences
  • "Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial," 2022, Journal of Antimicrobial Chemotherapy

MacLean frequently collaborates with several scientists whose repeated coauthorship indicates established partnerships. These include Rachel M. Wheatley, Julio Diaz Caballero, Natalia Kapel, Antonio Oliver, and Pramod K. Jangir.

Their research outputs are often published in notable scientific venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • The ISME Journal
  • eLife
  • Trends in Microbiology

Best Publications

  • Fitness Costs of Plasmids: a Limit to Plasmid Transmission

    Alvaro San Millan;R. Craig MacLean

  • The genetic basis of the fitness costs of antimicrobial resistance : : a meta-analysis approach

    Tom Vogwill;R. Craig MacLean

  • The evolution of antibiotic resistance

    R. Craig MacLean;Alvaro San Millan

  • Resource competition and social conflict in experimental populations of yeast.

    R. Craig MacLean;Ivana Gudelj

  • Beyond horizontal gene transfer: the role of plasmids in bacterial evolution.

    Jerónimo Rodríguez-Beltrán;Javier DelaFuente;Ricardo León-Sampedro;R Craig MacLean

  • The Beagle in a bottle

    Angus Buckling;R. Craig Maclean;Michael A. Brockhurst;Nick Colegrave

  • The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts

    R. Craig MacLean;Alex R. Hall;Gabriel G. Perron;Angus Buckling

  • Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids

    A. San Millan;R. Peña-Miller;R. Peña-Miller;M. Toll-Riera;Z. V. Halbert

  • Diversity and productivity peak at intermediate dispersal rate in evolving metacommunities

    Patrick Venail;R. C. MacLean;R. C. MacLean;T. Bouvier;M. A. Brockhurst

  • Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa

    R. C. MacLean;Gabriel G. Perron;Andy Gardner

  • The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens

    R. Craig MacLean;Graham Bell;Paul B. Rainey

  • Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria

    Alvaro San Millan;Jose Antonio Escudero;Jose Antonio Escudero;Danna R. Gifford;Didier Mazel;Didier Mazel

  • Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations

    Alvaro San Millan;Karl Heilbron;R Craig MacLean

  • Cooperation, competition and antibiotic resistance in bacterial colonies.

    Isabel Frost;Isabel Frost;William P. J. Smith;Sara Mitri;Alvaro San Millan

  • Interactions between horizontally acquired genes create a fitness cost in Pseudomonas aeruginosa

    Alvaro San Millan;Macarena Toll-Riera;Macarena Toll-Riera;Qin Qi;R. Craig MacLean

  • A mixture of "cheats" and "co-operators" can enable maximal group benefit

    R. Craig MacLean;Ayari Fuentes-Hernandez;Ayari Fuentes-Hernandez;Duncan Greig;Laurence D. Hurst

  • Evaluating evolutionary models of stress-induced mutagenesis in bacteria.

    R. Craig MacLean;Clara Torres-Barceló;Richard Moxon

  • Comparative Analysis of Myxococcus Predation on Soil Bacteria

    Andrew D. Morgan;R. Craig MacLean;Kristina L. Hillesland;Gregory J. Velicer

  • The distribution of fitness effects of beneficial mutations in Pseudomonas aeruginosa.

    R. Craig MacLean;Angus Buckling

  • Experimental Evolution of Pseudomonas fluorescens in Simple and Complex Environments

    Rowan D. H. Barrett;R. Craig MacLean;Graham Bell

Frequent Co-Authors

Graham Bell
Graham Bell McGill University
Angus Buckling
Angus Buckling University of Exeter
Andreas Wagner
Andreas Wagner University of Zurich
José R. Penadés
José R. Penadés Imperial College London
Didier Mazel
Didier Mazel Université Paris Cité
Antonio Oliver
Antonio Oliver Instituto de Salud Carlos III
Gail M. Preston
Gail M. Preston University of Oxford
Teresa M. Coque
Teresa M. Coque Instituto Ramón y Cajal de Investigación Sanitaria
Laurence D. Hurst
Laurence D. Hurst University of Bath
Rafael Cantón
Rafael Cantón Instituto Ramón y Cajal de Investigación Sanitaria

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