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Thomas H. Tötterman

Thomas H. Tötterman

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
8043
World Ranking
15301
National Ranking
232

Overview

Thomas H. Tötterman is affiliated with Uppsala University in Sweden. Their research primarily focuses on areas within Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. The scientist has contributed to the subfields of Genetics, Immunology, Pulmonary and Respiratory Medicine, and Molecular Biology.

Their work covers key topics including:

  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • Veterinary Oncology Research
  • RNA Interference and Gene Delivery

Among recent publications by Thomas H. Tötterman are:

  • "Adenoviral CD40 Ligand Immunotherapy in 32 Canine Malignant Melanomas-Long-Term Follow Up", 2021, Frontiers in Veterinary Science
  • "Intratumoral immunostimulatory AdCD40L gene therapy in patients with advanced solid tumors", 2020, Cancer Gene Therapy

The scientist frequently publishes in journals such as:

  • Frontiers in Veterinary Science
  • Cancer Gene Therapy

Collaborations are an element of their research profile, with recurrent coauthors including:

  • Angelica Loskog
  • Sara Saellström
  • Arian Sadeghi
  • Emma Eriksson
  • Thomas Segall

Best Publications

  • Phorbol ester-induced differentiation of chronic lymphocytic leukaemia cells.

    Thomas H. Tötterman;Kenneth Nilsson;Christer Sundström

  • Enhanced tumor eradication by combining CTLA-4 or PD-1 blockade with CpG therapy.

    Sara M. Mangsbo;Linda C. Sandin;Kerstin Anger;Alan J. Korman

  • Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.

    Justyna Leja;Ahmed Essaghir;Magnus Essand;Kenneth Wester

  • T-cell activation and subset patterns are altered in B-CLL and correlate with the stage of the disease

    Thomas H. Tötterman;Mats Carlsson;Bengt Simonsson;Mats Bengtsson

  • Human Bladder Carcinoma is Dominated by T-Regulatory Cells and Th1 Inhibitory Cytokines

    Angelica Loskog;Christina Ninalga;Gabriella Paul-Wetterberg;Manuel de la Torre

  • Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants

    Mats Engstrand;Claire Tournay;Marie A. Peyrat;Britt-Marie Eriksson

  • AdCD40L immunogene therapy for bladder carcinoma--the first phase I/IIa trial.

    Per-Uno Malmström;Angelica S.I. Loskog;Camilla A. Lindqvist;Sara M. Mangsbo

  • Mobilization of CD34+ cells by glycosylated and nonglycosylated G‐CSF in healthy volunteers — a comparative study

    M. Höglund;Bengt Smedmyr;Mats Bengtsson;Thomas H. Tötterman

  • Dose-dependent mobilisation of haematopoietic progenitor cells in healthy volunteers receiving glycosylated rHuG-CSF.

    M. Höglund;Bengt Smedmyr;Bengt Simonsson;Thomas H. Tötterman

  • The Human Agonistic CD40 Antibody ADC-1013 Eradicates Bladder Tumors and Generates T-cell–Dependent Tumor Immunity

    Sara M. Mangsbo;Sissela Broos;Erika Fletcher;Niina Veitonmäki

  • Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment.

    Angelica Loskog;Helena Dzojic;Sofia Vikman;Christina Ninalga

  • Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer.

    Linda C Sandin;Anna Orlova;Erika Gustafsson;Peter Ellmark

  • Cellular responses to cytomegalovirus in immunosuppressed patients: circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment.

    Mats Engstrand;Anna Karin Lidehäll;Thomas H. Tötterman;Björn Herrman

  • Drastically increased expression of MYC and FOS protooncogenes during in vitro differentiation of chronic lymphocytic leukemia cells

    Lars-Gunnar Larsson;Harry E. Gray;Thomas Totterman;Ulf Pettersson

  • Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo.

    Linda C. Sandin;Fredrik Eriksson;Peter Ellmark;Angelica S. I. Loskog

  • Stimulation of NK cell, T cell, and monocyte functions by the novel immunomodulator Linomide after autologous bone marrow transplantation. A pilot study in patients with acute myeloid leukemia.

    Mats Bengtsson;Bengt Simonsson;Kristina Carlsson;B O Nilsson

  • Regeneration of functional and activated NK and T sub-subset cells in the marrow and blood after autologous bone marrow transplantation: a prospective phenotypic study with 2/3-color FACS analysis.

    M Bengtsson;T H Tötterman;B Smedmyr;R Festin

  • CD40L - a multipotent molecule for tumor therapy

    Angelica Loskog;Thomas H Tötterman

  • Treatment efficacy and immune stimulation by AdCD40L gene therapy of spontaneous canine malignant melanoma.

    Sara Westberg;Arian Sadeghi;Emma Svensson;Thomas Segall

  • Surface Characteristics of the U-937 Human Histiocytic Lymphoma Cell Line: Specific Changes During Inducible Morphologic and Functional Differentiation In Vitro

    K. Nilsson;K. Forsbeck;M. Gidlund;C. Sundström

Frequent Co-Authors

Kenneth Nilsson
Kenneth Nilsson Uppsala University
Olle Korsgren
Olle Korsgren Uppsala University
Bo Nilsson
Bo Nilsson Uppsala University
Christer Sundström
Christer Sundström Uppsala University
Mats Bengtsson
Mats Bengtsson Royal Institute of Technology
Kjell Öberg
Kjell Öberg Uppsala University
Ulf Pettersson
Ulf Pettersson Uppsala University
Hans Wigzell
Hans Wigzell Karolinska Institute
John D. Lambris
John D. Lambris University of Pennsylvania
Erik G. Larsson
Erik G. Larsson Linköping University

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