World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
67
Citations
11838
World Ranking
2943
National Ranking
1361

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Neurotransmitter
  • Neuron

Shao Rui Chen focuses on Chemistry, Endocrinology, Internal medicine, Neuroscience and Neuropathic pain. His studies in Endocrinology integrate themes in fields like Neurotransmission, Ischemia and Resiniferatoxin. His study in the field of CATS, Artery and Heterotrimeric G protein also crosses realms of Hypercapnia and Sodium lactate.

Shao Rui Chen combines subjects such as DAMGO, Muscarinic acetylcholine receptor, Nociceptor and Opioid with his study of Neuroscience. Neuropathic pain is a primary field of his research addressed under Anesthesia. Shao Rui Chen usually deals with Excitatory postsynaptic potential and limits it to topics linked to Long-term potentiation and Postsynaptic potential and Hyperalgesia.

His most cited work include:

  • Gabapentin Suppresses Ectopic Nerve Discharges and Reverses Allodynia in Neuropathic Rats (174 citations)
  • Cardiac vanilloid receptor 1‐expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats (172 citations)
  • Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition (145 citations)

What are the main themes of his work throughout his whole career to date?

Shao Rui Chen spends much of his time researching Chemistry, Neuroscience, Internal medicine, Neuropathic pain and Endocrinology. His Chemistry study spans across into areas like Excitatory postsynaptic potential, Inhibitory postsynaptic potential, Glutamate receptor, Pharmacology and Anatomy. His Neuroscience study incorporates themes from Long-term potentiation, Glutamatergic, Posterior Horn Cell and Neurotransmission.

His study in the fields of Receptor, Potassium channel and CATS under the domain of Internal medicine overlaps with other disciplines such as Sympathetic nervous system. His Neuropathic pain research is multidisciplinary, relying on both Dorsal root ganglion, Spinal cord, Nerve injury and Nociception. As part of one scientific family, he deals mainly with the area of Endocrinology, narrowing it down to issues related to the Muscarinic acetylcholine receptor, and often Acetylcholine and Cholinergic.

He most often published in these fields:

  • Chemistry (48.21%)
  • Neuroscience (42.86%)
  • Internal medicine (37.50%)

What were the highlights of his more recent work (between 2017-2020)?

  • Dorsal root ganglion (23.21%)
  • Neuropathic pain (36.61%)
  • Glutamate receptor (21.43%)

In recent papers he was focusing on the following fields of study:

Shao Rui Chen mainly investigates Dorsal root ganglion, Neuropathic pain, Glutamate receptor, Nociception and Synaptic plasticity. His Dorsal root ganglion research includes elements of Nerve injury and Pharmacology. Within one scientific family, he focuses on topics pertaining to Chronic pain under Neuropathic pain, and may sometimes address concerns connected to Cancer research, Muscarinic acetylcholine receptor and Muscarine.

In his research, Shao Rui Chen undertakes multidisciplinary study on Glutamate receptor and Chemistry. His work carried out in the field of Synaptic plasticity brings together such families of science as Neuroscience and Neurotransmission. His Neuroscience research is multidisciplinary, incorporating elements of Long-term potentiation and Glutamatergic.

Between 2017 and 2020, his most popular works were:

  • The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions (81 citations)
  • Nerve Injury-Induced Chronic Pain Is Associated with Persistent DNA Methylation Reprogramming in Dorsal Root Ganglion. (25 citations)
  • μ-Opioid receptors in primary sensory neurons are essential for opioid analgesic effect on acute and inflammatory pain and opioid-induced hyperalgesia. (23 citations)

Best Publications

  • Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

    Wei Xiong;Tanxing Cui;Kejun Cheng;Fei Yang

  • Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats.

    G. M. Khan;Shao-Rui Chen;Hui-Lin Pan

  • The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions

    Jinjun Chen;Jinjun Chen;Lingyong Li;Shao Rui Chen;Hong Chen

  • Gabapentin Suppresses Ectopic Nerve Discharges and Reverses Allodynia in Neuropathic Rats

    Hui Lin Pan;James C. Eisenach;Shao Rui Chen

  • Targeting N-methyl-D-aspartate receptors for treatment of neuropathic pain

    Hong Yi Zhou;Shao Rui Chen;Hui Lin Pan

  • Cardiac vanilloid receptor 1‐expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats

    Matthew R. Zahner;De Pei Li;Shao Rui Chen;Hui Lin Pan

  • Modulation of pain transmission by G-protein-coupled receptors

    Hui Lin Pan;Hui Lin Pan;Zi Zhen Wu;Hong Yi Zhou;Shao Rui Chen

  • Hypersensitivity of Spinothalamic Tract Neurons Associated With Diabetic Neuropathic Pain in Rats

    Shao Rui Chen;Hui Lin Pan

  • Role of Presynaptic Muscarinic and GABAB Receptors in Spinal Glutamate Release and Cholinergic Analgesia in Rats

    De Pei Li;Shao Rui Chen;Yu Zhen Pan;Allan I. Levey

  • G9a is essential for epigenetic silencing of K+ channel genes in acute-to-chronic pain transition

    Geoffroy Olivier Laumet;Judit Garriga;Shao-Rui Chen;Yuhao Zhang

  • Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition

    De Pei Li;Shao Rui Chen;Hui Lin Pan

  • N-Methyl-d-aspartate Receptor- and Calpain-mediated Proteolytic Cleavage of K+-Cl− Cotransporter-2 Impairs Spinal Chloride Homeostasis in Neuropathic Pain

    Hong Yi Zhou;Shao Rui Chen;Hee Sun Byun;Hong Chen

  • Aminopyridines Potentiate Synaptic and Neuromuscular Transmission by Targeting the Voltage-activated Calcium Channel β Subunit

    Zi Zhen Wu;De Pei Li;Shao Rui Chen;Hui Lin Pan

  • Resiniferatoxin Induces Paradoxical Changes in Thermal and Mechanical Sensitivities in Rats: Mechanism of Action

    Hui Lin Pan;Ghous M. Khan;Kevin D. Alloway;Shao Rui Chen

  • Sensing Tissue Ischemia Another New Function for Capsaicin Receptors

    Hui Lin Pan;Shao Rui Chen

  • Opioid-Induced Long-Term Potentiation in the Spinal Cord Is a Presynaptic Event

    Hong Yi Zhou;Shao Rui Chen;Hong Chen;Hui Lin Pan

  • Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor.

    Xue Hong Cao;Hee Sun Byun;Shao Rui Chen;You Qing Cai

  • Intrathecal Clonidine Alleviates Allodynia in Neuropathic Rats Interaction with Spinal Muscarinic and Nicotinic Receptors

    Hui Lin Pan;Shao Rui Chen;James C. Eisenach

  • Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated calcium channels through calcium-dependent calcineurin in sensory neurons.

    Zi-Zhen Wu;Shao-Rui Chen;Hui-Lin Pan

  • A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons

    Amaresh Vydyanathan;Zi Zhen Wu;Shao Rui Chen;Hui Lin Pan

  • Role of protons in activation of cardiac sympathetic C-fibre afferents during ischaemia in cats.

    Hui Lin Pan;John C. Longhurst;James C. Eisenach;Shao Rui Chen

Frequent Co-Authors

Hui Lin Pan
Hui Lin Pan The University of Texas MD Anderson Cancer Center
Ke Ren
Ke Ren University of Maryland, Baltimore
Yun Guan
Yun Guan Johns Hopkins University School of Medicine
Jeffrey L. Noebels
Jeffrey L. Noebels Baylor College of Medicine
Kevin D. Alloway
Kevin D. Alloway Pennsylvania State University
John H. Peever
John H. Peever University of Toronto
Ken Mackie
Ken Mackie Indiana University
Allan I. Levey
Allan I. Levey Emory University
Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
C. Savio Chan
C. Savio Chan Northwestern University

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