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Neuroscience

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74
Citations
15491
World Ranking
2147
National Ranking
80

Medicine

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74
Citations
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19511
National Ranking
787

Overview

Sabatino Maione is affiliated with the University of Campania "Luigi Vanvitelli" in Italy and has a research portfolio focused primarily on medicine and neuroscience. Their work spans various subfields including physiology, pharmacology, cellular and molecular neuroscience, molecular biology, and neurology.

The scientist's research topics cover a range of key areas such as:

  • Pain Mechanisms and Treatments
  • Cannabis and Cannabinoid Research
  • Neuroscience and Neuropharmacology Research
  • Biochemical effects in animals
  • Pharmacological Effects of Natural Compounds
  • Neuropeptides and Animal Physiology
  • Botulinum Toxin and Related Neurological Disorders

Maione has frequently published in several scientific journals, emphasizing molecular sciences and pharmacology. These primary venues include:

  • International Journal of Molecular Sciences
  • Frontiers in Pharmacology
  • Neuropharmacology
  • Biomolecules
  • Biomedicine & Pharmacotherapy

Collaboration is a significant aspect of Maione's scientific activity, with several frequent coauthors contributing to their body of work. These collaborators include:

  • Livio Luongo
  • Serena Boccella
  • Francesca Guida
  • Carmela Belardo
  • Rosmara Infantino

Selected recent research papers authored or coauthored by Sabatino Maione illustrate their focused interests. Notable examples include:

  • Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain, 2020, International Journal of Molecular Sciences
  • Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol, 2020, Scientific Reports
  • VEGF-A/VEGFR-1 signalling and chemotherapy-induced neuropathic pain: therapeutic potential of a novel anti-VEGFR-1 monoclonal antibody, 2021, Journal of Experimental & Clinical Cancer Research
  • Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice, 2021, Nature Communications
  • Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT1A and CB1 receptors, 2021, Brain Research Bulletin

This research contributes to understanding the mechanisms and treatments of pain, the effects of cannabinoids, and neurophysiological changes associated with different pathological conditions. The work spans experimental approaches involving behavioral, biochemical, and molecular techniques.

Best Publications

  • Forebrain pain mechanisms.

    Volker Neugebauer;Vasco Galhardo;Sabatino Maione;Sean C. Mackey

  • Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors

    Sabatino Maione;Tiziana Bisogno;Vito de Novellis;Enza Palazzo

  • Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

    F. Guida;F. Turco;M. Iannotta;D. De Gregorio

  • Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

    Danilo De Gregorio;Ryan J. McLaughlin;Luca Posa;Rafael Ochoa-Sanchez

  • Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats

    Stefania Petrosino;Enza Palazzo;Vito de Novellis;Tiziana Bisogno

  • Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors

    S Maione;L De Petrocellis;V de Novellis;A Schiano Moriello

  • Non‐psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action

    Sabatino Maione;Fabiana Piscitelli;Luisa Gatta;Daniela Vita

  • A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ 9 -tetrahydrocannabinol: Δ 9 -Tetrahydrocannabiphorol

    Cinzia Citti;Pasquale Linciano;Fabiana Russo;Livio Luongo

  • Tonic Endovanilloid Facilitation of Glutamate Release in Brainstem Descending Antinociceptive Pathways

    Katarzyna Starowicz;Sabatino Maione;Luigia Cristino;Enza Palazzo

  • Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.

    Joshua W. Little;Amanda Ford;Ashley M. Symons-Liguori;Zhoumou Chen

  • The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption

    F. Rossi;D. Siniscalco;L. Luongo;L. De Petrocellis

  • The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

    Daniele Bolognini;Daniele Bolognini;Barbara Costa;S. Maione;Francesca Comelli

  • Interaction between vanilloid and glutamate receptors in the central modulation of nociception.

    Enza Palazzo;Vito de Novellis;Ida Marabese;Dario Cuomo

  • Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain.

    Dario Siniscalco;Carlo Fuccio;Catia Giordano;Franca Ferraraccio

  • 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c] pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice

    L. Luongo;E. Palazzo;S. Tambaro;C. Giordano

  • Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

    F. Guida;L. Luongo;F. Marmo;R. Romano

  • Long-Lasting Effects of Human Mesenchymal Stem Cell Systemic Administration on Pain-Like Behaviors, Cellular, and Biomolecular Modifications in Neuropathic Mice

    Dario Siniscalco;Catia Giordano;Umberto Galderisi;Livio Luongo

  • Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception.

    E. Palazzo;I. Marabese;V. de Novellis;P. Oliva

  • Role of neurotrophins in neuropathic pain.

    Dario Siniscalco;Catia Giordano;Francesco Rossi;Sabatino Maione

  • Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor.

    F Guida;L Luongo;S Boccella;M E Giordano

  • The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component.

    Patrizia Oliva;Caterina Aurilio;Francesco Massimo;Antonio Grella

  • Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors.

    Enza Palazzo;Yu Fu;Guangchen Ji;Sabatino Maione

Frequent Co-Authors

Livio Luongo
Livio Luongo University of Campania "Luigi Vanvitelli"
Enza Palazzo
Enza Palazzo University of Campania "Luigi Vanvitelli"
Vito de Novellis
Vito de Novellis University of Campania "Luigi Vanvitelli"
Vincenzo Di Marzo
Vincenzo Di Marzo National Research Council (CNR)
Francesca Rossi
Francesca Rossi University of Campania "Luigi Vanvitelli"
Luigia Cristino
Luigia Cristino National Research Council (CNR)
Stefania Petrosino
Stefania Petrosino National Research Council (CNR)
Antonio Lavecchia
Antonio Lavecchia University of Naples Federico II
Alessandro Usiello
Alessandro Usiello University of Campania "Luigi Vanvitelli"
Evangelista Sagnelli
Evangelista Sagnelli University of Campania "Luigi Vanvitelli"

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