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Overview

Livio Luongo is affiliated with the University of Campania "Luigi Vanvitelli" in Italy. Their research work spans the fields of Medicine and Neuroscience, with substantial contributions to subfields such as Physiology, Pharmacology, Cellular and Molecular Neuroscience, Molecular Biology, and Neurology.

Their main research topics include:

  • Pain Mechanisms and Treatments
  • Cannabis and Cannabinoid Research
  • Neuroscience and Neuropharmacology Research
  • Neuropeptides and Animal Physiology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Biochemical effects in animals
  • Pharmacological Effects of Natural Compounds

Frequent co-authors with whom Luongo collaborates include Sabatino Maione, Francesca Guida, Serena Boccella, Carmela Belardo, and Rosmara Infantino.

Their recent scientific publications cover various aspects of neuropathic pain, cannabinoid research, and neurobiology, such as:

  • "Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain" (2020) published in International Journal of Molecular Sciences
  • "Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol" (2020) published in Scientific Reports
  • "MED1/BDNF/TrkB pathway is involved in thalamic hemorrhage-induced pain and depression by regulating microglia" (2022) published in Neurobiology of Disease
  • "Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT1A and CB1 receptors" (2021) published in Brain Research Bulletin
  • "Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuit alteration: a comparative observational study in mice" (2021) published in Pain

Luongo has published extensively in journals including Frontiers in Pharmacology, International Journal of Molecular Sciences, Biomedicine & Pharmacotherapy, Biomolecules, and Neuropharmacology. Their work also extends into book contributions, such as the recent 2023 publication by Frontiers Media titled "Glial Cells, Maladaptive Plasticity and Neurodegeneration: Mechanisms, Targeted Therapies and Future Directions, 2nd Edition."

Best Publications

  • Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

    F. Guida;F. Turco;M. Iannotta;D. De Gregorio

  • A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ 9 -tetrahydrocannabinol: Δ 9 -Tetrahydrocannabiphorol

    Cinzia Citti;Pasquale Linciano;Fabiana Russo;Livio Luongo

  • Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.

    Joshua W. Little;Amanda Ford;Ashley M. Symons-Liguori;Zhoumou Chen

  • The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption

    F. Rossi;D. Siniscalco;L. Luongo;L. De Petrocellis

  • Role of reactive oxygen species and spinal cord apoptotic genes in the development of neuropathic pain.

    Dario Siniscalco;Carlo Fuccio;Catia Giordano;Franca Ferraraccio

  • 1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c] pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice

    L. Luongo;E. Palazzo;S. Tambaro;C. Giordano

  • Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

    F. Guida;L. Luongo;F. Marmo;R. Romano

  • Long-Lasting Effects of Human Mesenchymal Stem Cell Systemic Administration on Pain-Like Behaviors, Cellular, and Biomolecular Modifications in Neuropathic Mice

    Dario Siniscalco;Catia Giordano;Umberto Galderisi;Livio Luongo

  • Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor.

    F Guida;L Luongo;S Boccella;M E Giordano

  • Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.

    Zhoumou Chen;Timothy M. Doyle;Livio Luongo;Tally M. Largent-Milnes

  • Intra-brain microinjection of human mesenchymal stem cells decreases allodynia in neuropathic mice

    Dario Siniscalco;Catia Giordano;Umberto Galderisi;Livio Luongo

  • The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats

    Vito de Novellis;Daniela Vita;Luisa Gatta;Livio Luongo

  • Behavioral, Biochemical and Electrophysiological Changes in Spared Nerve Injury Model of Neuropathic Pain.

    Francesca Guida;Danilo De Gregorio;Enza Palazzo;Flavia Ricciardi

  • Palmitoylethanolamide Reduces Granuloma-Induced Hyperalgesia by Modulation of Mast Cell Activation in Rats

    Daniele De Filippis;Livio Luongo;Mariateresa Cipriano;Enza Palazzo

  • Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice.

    Livio Luongo;Francesca Guida;Serena Boccella;Giulia Bellini

  • TRPV1-Dependent and -Independent Alterations in the Limbic Cortex of Neuropathic Mice: Impact on Glial Caspases and Pain Perception

    Catia Giordano;Luigia Cristino;Livio Luongo;Dario Siniscalco

  • Moving towards Supraspinal TRPV1 Receptors for Chronic Pain Relief

    Enza Palazzo;Livio Luongo;Vito de Novellis;Liberato Berrino

  • The A1 adenosine receptor as a new player in microglia physiology

    L. Luongo;F. Guida;R. Imperatore;F. Napolitano

  • Transient receptor potential vanilloid type 1 and pain development

    Enza Palazzo;Livio Luongo;Vito de Novellis;Francesco Rossi

  • Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels

    Francesca Rossi;Silverio Perrotta;Giulia Bellini;Livio Luongo

  • Antineuropathic Profile of N-Palmitoylethanolamine in a Rat Model of Oxaliplatin-Induced Neurotoxicity

    Lorenzo Di Cesare Mannelli;Alessandra Pacini;Francesca Corti;Serena Boccella

  • Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain

    Francesca Guida;Serena Boccella;Carmela Belardo;Monica Iannotta

Frequent Co-Authors

Sabatino Maione
Sabatino Maione University of Campania "Luigi Vanvitelli"
Vito de Novellis
Vito de Novellis University of Campania "Luigi Vanvitelli"
Enza Palazzo
Enza Palazzo University of Campania "Luigi Vanvitelli"
Luigia Cristino
Luigia Cristino National Research Council (CNR)
Alessandro Usiello
Alessandro Usiello University of Campania "Luigi Vanvitelli"
Marzia Malcangio
Marzia Malcangio King's College London
Giuseppe Gigli
Giuseppe Gigli University of Salento
Todd W. Vanderah
Todd W. Vanderah University of Arizona

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