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Albert J. R. Heck

Albert J. R. Heck

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Chemistry
Netherlands
2025

D-Index & Metrics

Chemistry

D-Index
132
Citations
66515
World Ranking
294
National Ranking
11

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award
  • 2017 - Spinoza Prize, Dutch Research Council
  • 2014 - Royal Netherlands Academy of Arts and Sciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Albert J. R. Heck is affiliated with Utrecht University in the Netherlands and has a significant body of research in the fields of biochemistry, genetics, molecular biology, and medicine. Their publications extensively cover subfields such as molecular biology, spectroscopy, radiology, nuclear medicine, imaging, immunology, and infectious diseases.

The scientist's work spans multiple key topics including monoclonal and polyclonal antibodies research, mass spectrometry techniques and applications, glycosylation and glycoproteins research, advanced proteomics techniques and applications, mitochondrial function and pathology, SARS-CoV-2 and COVID-19 research, and blood groups and transfusion.

Recent publications include:

  • "High-Resolution Native Mass Spectrometry" (2021, Chemical Reviews)
  • "High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells" (2020, Cell)
  • "Resolving heterogeneous macromolecular assemblies by Orbitrap-based single-particle charge detection mass spectrometry" (2020, Nature Methods)
  • "Adeno-associated virus capsid assembly is divergent and stochastic" (2021, Nature Communications)
  • "Structural specializations of the sperm tail" (2023, Cell)

Frequent co-authors working alongside Albert J. R. Heck include:

  • Albert Bondt
  • Maurits A. den Boer
  • Johannes F. Hevler
  • Sem Tamara
  • Joost Snijder

Their publications have appeared most frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular & Cellular Proteomics
  • Nature Communications
  • FEBS Journal
  • Analytical Chemistry

Albert J. R. Heck has received several notable awards, including the Spinoza Prize from the Dutch Research Council in 2017, membership in the Royal Netherlands Academy of Arts and Sciences since 2014, and is a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

    Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert

  • Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics.

    Paul J Boersema;Reinout Raijmakers;Simone Lemeer;Simone Lemeer;Shabaz Mohammed

  • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

    Wim De Lau;Nick Barker;Nick Barker;Teck Y. Low;Bon Kyoung Koo

  • Selective Isolation at the Femtomole Level of Phosphopeptides from Proteolytic Digests Using 2D-NanoLC-ESI-MS/MS and Titanium Oxide Precolumns

    Martijn W. H. Pinkse;Pauliina M. Uitto;Martijn J. Hilhorst;and Bert Ooms

  • Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.

    Bon-Kyoung Koo;Maureen Spit;Ingrid Jordens;Teck Y. Low

  • Next-generation proteomics: towards an integrative view of proteome dynamics

    A. F. Maarten Altelaar;Javier Munoz;Albert J. R. Heck

  • Native mass spectrometry: a bridge between interactomics and structural biology.

    Albert J R Heck

  • Complement is activated by IgG hexamers assembled at the cell surface.

    Christoph A. Diebolder;Christoph A. Diebolder;Frank J. Beurskens;Rob N. de Jong;Roman I. Koning

  • The minimum information about a proteomics experiment (MIAPE)

    Chris F. Taylor;Chris F. Taylor;Norman W. Paton;Norman W. Paton;Kathryn S. Lilley;Kathryn S. Lilley;Pierre Alain Binz;Pierre Alain Binz

  • Quantitative Phosphoproteomics of Early Elicitor Signaling in Arabidopsis

    Joris J. Benschop;Shabaz Mohammed;Martina O'Flaherty;Albert J.R. Heck

  • Investigation of intact protein complexes by mass spectrometry.

    Albert J. R. Heck;Robert H. H. van den Heuvel

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Native Mass Spectrometry: What is in the Name?

    Aneika C. Leney;Albert J. R. Heck

  • Ion mobility mass spectrometry of proteins and protein assemblies.

    Charlotte Uetrecht;Rebecca J. Rose;Esther van Duijn;Kristina Lorenzen

  • Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

    Fan Liu;Dirk T S Rijkers;Harm Post;Albert J R Heck

  • Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice

    Ernie de Boer;Patrick Rodriguez;Edgar Bonte;Jeroen Krijgsveld

  • Six alternative proteases for mass spectrometry-based proteomics beyond trypsin

    Piero Giansanti;Liana Tsiatsiani;Teck Yew Low;Albert J R Heck

  • Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics

    Jeroen Krijgsveld;René F Ketting;Tokameh Mahmoudi;Tokameh Mahmoudi;Janik Johansen

  • Toward a comprehensive characterization of a human cancer cell phosphoproteome

    Houjiang Zhou;Serena Di Palma;Christian Preisinger;Mao Peng

  • Mass Spectrometry–Based Proteomics and Network Biology

    Ariel Bensimon;Albert J. R. Heck;Ruedi Aebersold

  • Imaging techniques for the study of chemical reaction dynamics.

    Albert J. R. Heck;David W. Chandler

  • High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies.

    Rebecca J Rose;Eugen Damoc;Eduard Denisov;Alexander Makarov

Frequent Co-Authors

Nico M. M. Nibbering
Nico M. M. Nibbering Vrije Universiteit Amsterdam

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