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Richard W. Strange

Richard W. Strange

D-Index & Metrics

Chemistry

D-Index
50
Citations
7151
World Ranking
14587
National Ranking
816

Overview

Richard W. Strange is affiliated with the University of Essex in the United Kingdom. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Periodontics, Infectious Diseases, Materials Chemistry, and Cell Biology.

The scientist has contributed to topics including:

  • Oral microbiology and periodontitis research
  • Clostridium difficile and Clostridium perfringens research
  • Enzyme Structure and Function
  • Hemoglobin structure and function
  • Photosynthetic Processes and Mechanisms
  • Streptococcal Infections and Treatments
  • Porphyrin Metabolism and Disorders

Selected recent papers authored or co-authored by Richard W. Strange cover various aspects of enzyme structure, microbial proteins, and catalytic materials:

  • Prevotella intermedia produces two proteins homologous to Porphyromonas gingivalis HmuY but with different heme coordination mode, 2020, Biochemical Journal
  • Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature, 2022, IUCrJ
  • Bacteroides fragilis expresses three proteins similar to Porphyromonas gingivalis HmuY: Hemophore-like proteins differentially evolved to participate in heme acquisition in oral and gut microbiomes, 2023, The FASEB Journal
  • Computational infrared and Raman spectra by hybrid QM/MM techniques: a study on molecular and catalytic material systems, 2023, Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis, 2020, Chemical Science

Frequent collaborators include Michael A. Hough, S.V. Antonyuk, Klaudia Siemińska, Michał Śmiga, and Teresa Olczak. Collaboration patterns suggest a focus on structural and functional biochemistry, particularly related to microbial proteins and enzyme catalysis.

Richard W. Strange's work has been published in a range of scientific journals known for their focus on biochemistry and molecular biology, including:

  • Biochemical Journal
  • IUCrJ
  • The FASEB Journal
  • Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • Chemical Science

Best Publications

  • Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS

    Jennifer Stine Elam;Alexander B Taylor;Richard Strange;Svetlana Antonyuk

  • Constrained and Restrained Refinement in EXAFS Data Analysis with Curved Wave Theory

    Norman Binsted;Richard W. Strange;S. Samar Hasnain

  • The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis.

    Richard W. Strange;Svetlana Antonyuk;Michael A. Hough;Peter A. Doucette

  • Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

    Michael A. Hough;J. Günter Grossmann;Svetlana V. Antonyuk;Richard W. Strange

  • Variable metallation of human superoxide dismutase: atomic resolution crystal structures of Cu-Zn, Zn-Zn and as-isolated wild-type enzymes.

    Richard W. Strange;Svetlana V. Antonyuk;Michael A. Hough;Peter A. Doucette

  • Atomic Resolution Structures of Resting-State, Substrate- and Product-Complexed Cu-Nitrite Reductase Provide Insight Into Catalytic Mechanism

    Svetlana V. Antonyuk;Richard W. Strange;Gary Sawers;Robert R. Eady

  • Dioxygen−copper reactivity: generation, characterization, and reactivity of a hydroperoxo−dicopper(II) complex

    Kenneth D. Karlin;Phalguni. Ghosh;Richard W. Cruse;Amjad. Farooq

  • X-ray Absorption Spectroscopy of Metal-Histidine Coordination in Metalloproteins. Exact Simulation of the EXAFS of Tetrakis(imidazole)copper(II) Nitrate and Other Copper-Imidazole Complexes by the Use of a Multiple-Scattering Treatment

    Richard W. Strange;Ninian J. Blackburn;P. F. Knowles;S. Samar Hasnain

  • The Structure of Human Extracellular Copper–Zinc Superoxide Dismutase at 1.7 Å Resolution: Insights into Heparin and Collagen Binding

    Svetlana V. Antonyuk;Richard W. Strange;Stefan L. Marklund;S. Samar Hasnain

  • XAFS study of the high-affinity copper-binding site of human PrP91–231 and its low-resolution structure in solution

    SS Hasnain;LM Murphy;RW Strange;JG Grossmann

  • Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.

    S. V. Antonyuk;C. R. Trevitt;R. W. Strange;G. S. Jackson

  • Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

    Xiaohang Cao;Svetlana V. Antonyuk;Sai V. Seetharaman;Lisa J. Whitson

  • Structural and kinetic evidence for an ordered mechanism of copper nitrite reductase

    Richard W Strange;Loretta M Murphy;Fraser E Dodd;Zelda H.L Abraham

  • Insights into the structure and domain flexibility of full-length pro-matrix metalloproteinase-9/gelatinase B.

    Gabriel Rosenblum;Philippe E. Van den Steen;Sidney R. Cohen;J. Günter Grossmann

  • Ligand Binding and Aggregation of Pathogenic Sod1.

    Gareth S.A. Wright;Svetlana V. Antonyuk;Neil M. Kershaw;Richard W. Strange

  • Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1

    Michael J. Capper;Paul M. O’Neill;Nicholas Fisher;Richard W. Strange

  • Chemistry and structural studies on the dioxygen-binding copper-1,2-dimethylimidazole system

    Indrajit Sanyal;Kenneth D. Karlin;Richard W. Strange;Ninian J. Blackburn

  • Copper K-extended x-ray absorption fine structure studies of oxidized and reduced dopamine beta-hydroxylase. Confirmation of a sulfur ligand to copper(I) in the reduced enzyme.

    N.J. Blackburn;S.S. Hasnain;T.M. Pettingill;R.W. Strange

  • An e.x.a.f.s. study of the manganese O2-evolving complex in purified Photosystem II membrane fractions. The S1 and S2 states.

    D J MacLachlan;B J Hallahan;S V Ruffle;J H A Nugent

  • Role of the axial ligand in type 1 Cu centers studied by point mutations of met148 in rusticyanin.

    John F. Hall;Lalji D. Kanbi;Richard W. Strange;S. Samar Hasnain

Frequent Co-Authors

S. Samar Hasnain
S. Samar Hasnain University of Liverpool
Robert R. Eady
Robert R. Eady University of Liverpool
Ninian J. Blackburn
Ninian J. Blackburn Oregon Health & Science University
Kenneth D. Karlin
Kenneth D. Karlin Johns Hopkins University
Joan Selverstone Valentine
Joan Selverstone Valentine University of California, Los Angeles
P. John Hart
P. John Hart The University of Texas Health Science Center at San Antonio
Seiki Kuramitsu
Seiki Kuramitsu Osaka University
Gary Sawers
Gary Sawers Martin Luther University Halle-Wittenberg
Peter F. Knowles
Peter F. Knowles University of Leeds

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