World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
73
Citations
18851
World Ranking
2047
National Ranking
254

Overview

Nigel P. Minton is affiliated with the University of Nottingham in the United Kingdom. Their research spans multiple domains within biochemistry, genetics, and molecular biology, with significant contributions also in medicine. A substantial part of their work centers on molecular biology, infectious diseases, biomedical engineering, environmental engineering, and genetics.

Their expertise covers a broad range of topics, including:

  • Microbial Metabolic Engineering and Bioproduction
  • Clostridium difficile and Clostridium perfringens research
  • Biofuel production and bioconversion
  • CRISPR and Genetic Engineering
  • Enzyme Catalysis and Immobilization
  • Microbial Fuel Cells and Bioremediation
  • Viral gastroenteritis research and epidemiology

Their recent publications include:

  • "A genome-wide approach for identification and characterisation of metabolite-inducible systems," 2020, Nature Communications
  • "Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection," 2021, Nature Communications
  • "Pathogenicity and virulence of Clostridium botulinum," 2023, Virulence
  • "Synthetic Biology on Acetogenic Bacteria for Highly Efficient Conversion of C1 Gases to Biochemicals," 2020, International Journal of Molecular Sciences
  • "Genetic and metabolic engineering challenges of C1-gas fermenting acetogenic chassis organisms," 2021, FEMS Microbiology Reviews

Frequent co-authors in Nigel P. Minton's research include:

  • Sarah A. Kuehne
  • Christopher M. Humphreys
  • Klaus Winzer
  • Terry W. Bilverstone
  • Jonathan Baker

The scientist commonly publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Synthetic Biology
  • Frontiers in Bioengineering and Biotechnology
  • Nature Communications
  • Metabolic Engineering

Best Publications

  • The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

    Mohammed Sebaihia;Brendan W Wren;Peter Mullany;Neil F Fairweather

  • The role of toxin A and toxin B in Clostridium difficile infection

    Sarah A. Kuehne;Stephen T. Cartman;John T. Heap;Michelle L. Kelly

  • The ClosTron: a universal gene knock-out system for the genus Clostridium.

    John T. Heap;Oliver J. Pennington;Stephen T. Cartman;Glen P. Carter

  • The pMTL nic− cloning vectors. I: Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing

    Steve P. Chambers;Sue E. Prior;David A. Barstow;Nigel P. Minton

  • A modular system for Clostridium shuttle plasmids.

    John T. Heap;Oliver J. Pennington;Stephen T. Cartman;Nigel P. Minton

  • The ClosTron: Mutagenesis in Clostridium refined and streamlined.

    John T. Heap;Sarah A. Kuehne;Muhammad Ehsaan;Stephen T. Cartman

  • Improved plasmid vectors for the isolation of translational lac gene fusions.

    Nigel P. Minton

  • Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier.

    Des Purdy;Triona A. T. O'Keeffe;Michael Elmore;Mike Herbert

  • Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile

    Tanja Ðapa;Rosanna Leuzzi;Yen K. Ng;Soza T. Baban

  • Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes

    Mohammed Sebaihia;Michael W. Peck;Nigel P. Minton;Nicholas R. Thomson

  • Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis.

    S C Liu;N P Minton;A J Giaccia;J M Brown

  • Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the tcdC Genotype and Toxin Production

    Stephen T. Cartman;Michelle L. Kelly;Daniela Heeg;John T. Heap

  • EXPRESSION OF THE BACTERIAL NITROREDUCTASE ENZYME IN MAMMALIAN CELLS RENDERS THEM SELECTIVELY SENSITIVE TO KILLING BY THE PRODRUG CB1954

    J.A. Bridgewater;C.J. Springer;R.J. Knox;N.P. Minton

  • Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment.

    MJ Lemmon;P van Zijl;ME Fox;ML Mauchline

  • Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia

    M E Fox;M J Lemmon;M L Mauchline;T O Davis

  • Femtomolar Sensitivity of a NO Sensor from Clostridium botulinum

    Pierre Nioche;Vladimir Berka;Julia Vipond;Nigel Minton

  • Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

    Sarah A. Kuehne;Mark M. Collery;Michelle L. Kelly;Stephen T. Cartman

  • Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker

    John T. Heap;Muhammad Ehsaan;Clare M. Cooksley;Yen-Kuan Ng

  • Clostridia in Cancer Therapy

    Nigel P. Minton

  • Metabolic engineering of Clostridium autoethanogenum for selective alcohol production

    Fungmin Liew;Anne M. Henstra;Michael Kӧpke;Klaus Winzer

Frequent Co-Authors

Klaus Winzer
Klaus Winzer University of Nottingham
Sheng Yang
Sheng Yang Chinese Academy of Sciences
Philippe Lambin
Philippe Lambin Maastricht University
Daniel Paredes-Sabja
Daniel Paredes-Sabja Texas A&M University
Peter Dürre
Peter Dürre University of Ulm
Amato J. Giaccia
Amato J. Giaccia Stanford University
Richard W. Titball
Richard W. Titball University of Exeter
Hannu Korkeala
Hannu Korkeala University of Helsinki
Harry J. Gilbert
Harry J. Gilbert Newcastle University
Rolf Daniel
Rolf Daniel University of Göttingen

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