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Chemistry

D-Index
56
Citations
13919
World Ranking
11475
National Ranking
3103

Overview

Erik J. Sorensen is affiliated with Princeton University in the United States. Their research primarily spans the fields of Chemistry and Biochemistry, Genetics and Molecular Biology, with a particular focus on Organic Chemistry and Molecular Biology at the subfield level. Additional subfields include Pharmacology, Materials Chemistry, and Biomedical Engineering.

The scientist's work addresses multiple topics, including:

  • Catalytic C-H Functionalization Methods
  • Computational Drug Discovery Methods
  • Pharmacogenetics and Drug Metabolism
  • Microbial Natural Products and Biosynthesis
  • Marine Sponges and Natural Products
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography

Erik J. Sorensen has published extensively, with recent notable papers including:

  • "Pd(II)-Catalyzed Synthesis of Benzocyclobutenes by β-Methylene-Selective C(sp3)-H Arylation with a Transient Directing Group," 2021, Journal of the American Chemical Society
  • "A Concise Synthesis of Pleurotin Enabled by a Nontraditional C-H Epimerization," 2022, Journal of the American Chemical Society
  • "N-Oxide-to-Carbon Transmutations of Azaarene N-Oxides," 2024, Organic Letters
  • "Cyclization by C(sp3)-H Arylation with a Transient Directing Group for the Diastereoselective Preparation of Indanes," 2021, ACS Catalysis
  • "Importance of asparagine-381 and arginine-487 for substrate recognition in CYP4Z1," 2020, Biochemical Pharmacology

Frequent coauthors collaborating with Sorensen include:

  • John Hoskin
  • Matthias Bureik
  • Huw M. L. Davies
  • Jin-Quan Yu
  • Gerhard Wolber

Their publications are frequently found in the following venues:

  • Organic Letters
  • The Cambridge Structural Database
  • Journal of the American Chemical Society
  • Applied Biochemistry and Biotechnology
  • ACS Catalysis

Best Publications

  • Classics in total synthesis : targets, strategies, methods

    K. C. Nicolaou;E. J. Sorensen;E. J. Corey;Scott A. Snyder

  • Total synthesis of taxol

    K. C. Nicolaou;K. C. Nicolaou;Z. Yang;J. J. Liu;H. Ueno

  • Recent applications of C–H functionalization in complex natural product synthesis

    Dylan J. Abrams;Philip A. Provencher;Erik J. Sorensen

  • Palladium-catalyzed ring-forming aminoacetoxylation of alkenes.

    Erik J. Alexanian;Chulbom Lee;Erik J. Sorensen

  • Total Synthesis of (–)‐Epothilone A

    Aaron Balog;Dongfang Meng;Ted Kamenecka;Peter Bertinato

  • Total Syntheses of Epothilones A and B

    Dongfang Meng;Peter Bertinato;Aaron Balog;Dai Shi Su

  • Total Synthesis of Taxol. 2. Construction of A and C Ring Intermediates and Initial Attempts To Construct the ABC Ring System

    K. C. Nicolaou;J. J. Liu;Z. Yang;H. Ueno

  • Protein-reactive natural products.

    Carmen Drahl;Benjamin F. Cravatt;Erik J. Sorensen

  • Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype.

    Gregory C. Adam;Erik J. Sorensen;Benjamin F. Cravatt

  • Total Synthesis of Taxol. 1. Retrosynthesis, Degradation, and Reconstitution

    K. C. Nicolaou;P. G. Nantermet;H. Ueno;R. K. Guy

  • REMOTE EFFECTS IN MACROLIDE FORMATION THROUGH RING-FORMING OLEFIN METATHESIS : AN APPLICATION TO THE SYNTHESIS OF FULLY ACTIVE EPOTHILONE CONGENERS

    Dongfang Meng;Dai-Shi Su;Aaron Balog;Peter Bertinato

  • Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling

    Michael J Evans;Alan Saghatelian;Erik J Sorensen;Benjamin F Cravatt

  • Total Synthesis of (–)‐Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

    Dai Shi Su;Dongfang Meng;Dongfang Meng;Peter Bertinato;Aaron Balog

  • Synthesis of epothilones, intermediates thereto, analogues and uses thereof

    Samuel J. Danishefsky;Peter Bertinato;Dai-Shi Su;Dang Fang Meng

  • Chemical Strategies for Functional Proteomics

    Gregory C. Adam;Erik J. Sorensen;Benjamin F. Cravatt

  • Acceptorless dehydrogenation of small molecules through cooperative base metal catalysis

    Julian G. West;David Huang;Erik J. Sorensen

  • Chemical strategies for the global analysis of protein function.

    Benjamin F Cravatt;Erik J Sorensen

  • Profiling the specific reactivity of the proteome with non-directed activity-based probes.

    Gregory C. Adam;Benjamin F. Cravatt;Erik J. Sorensen

  • The Uranyl Cation as a Visible-Light Photocatalyst for C(sp(3) )-H Fluorination.

    Julian G. West;T. Aaron Bedell;Erik J. Sorensen

  • Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites

    Rubén M Buey;Enrique Calvo;Isabel Barasoain;Oriol Pineda

  • An enantioselective synthesis of FR182877 provides a chemical rationalization of its structure and affords multigram quantities of its direct precursor.

    Christopher D. Vanderwal;David A. Vosburg;Sven Weiler;Erik J. Sorensen

Frequent Co-Authors

K. C. Nicolaou
K. C. Nicolaou Rice University
Benjamin F. Cravatt
Benjamin F. Cravatt Scripps Research Institute
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Ting-Chao Chou
Ting-Chao Chou Memorial Sloan Kettering Cancer Center
Zhen Yang
Zhen Yang Peking University
Huw M. L. Davies
Huw M. L. Davies Emory University
Ernest Hamel
Ernest Hamel National Institutes of Health
Susan Band Horwitz
Susan Band Horwitz Albert Einstein College of Medicine
Gerhard Wolber
Gerhard Wolber Freie Universität Berlin
Edward A. Anderson
Edward A. Anderson University of Oxford

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