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Yoshio Hirabayashi

Yoshio Hirabayashi

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
15000
World Ranking
7121
National Ranking
484

Overview

Yoshio Hirabayashi is affiliated with RIKEN in Japan and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Their research spans various subfields including Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Cell Biology, and Neurology.

The scientist has published prominently on topics related to sphingolipid metabolism and signaling, lysosomal storage disorders, lipid membrane structure and behavior, receptor mechanisms and signaling, glycosylation and glycoproteins, neuroscience and neuropharmacology, as well as cerebrospinal fluid and hydrocephalus. These areas reflect a multidisciplinary approach to understanding cellular biochemistry and neurological processes.

Frequent co-authors include Hiroyuki Kamiguchi, Peter Greimel, Hisako Akiyama, Koki Kano, and Ichiro Matsuo, with collaboration counts ranging from 7 to 10 publications each. Their published research appears in several notable venues such as Biochemical and Biophysical Research Communications, Journal of Biological Chemistry, Organic & Biomolecular Chemistry, Molecular Metabolism, and Gastroenterology.

Selected recent papers authored by or involving Yoshio Hirabayashi include:

  • Roles of GPRC5 family proteins: focusing on GPRC5B and lipid-mediated signalling, 2020, The Journal of Biochemistry
  • Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes, 2020, Molecular Metabolism
  • Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol, 2020, Journal of Biological Chemistry
  • Evidence for Altered Metabolism of Sphingosine-1-Phosphate in the Corpus Callosum of Patients with Schizophrenia, 2020, Schizophrenia Bulletin
  • Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk, 2023, Gastroenterology

Best Publications

  • Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis.

    Shinichi Ichikawa;Hisako Sakiyama;Gen Suzuki;Kazuya I. P. Jwa Hidari

  • A Bilirubin-Inducible Fluorescent Protein from Eel Muscle

    Akiko Kumagai;Ryoko Ando;Hideyuki Miyatake;Peter Greimel

  • 3-Phosphoglycerate dehydrogenase, a key enzyme for L-serine biosynthesis, is preferentially expressed in the radial glia/astrocyte lineage and olfactory ensheathing glia in the mouse brain

    Miwako Yamasaki;Keiko Yamada;Shigeki Furuya;Junya Mitoma

  • Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer

    Hideyoshi Higashi;Yoshio Hirabayashi;Yukio Fukui;Masaharu Naiki

  • L-serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons.

    Shigeki Furuya;Toshihide Tabata;Junya Mitoma;Keiko Yamada

  • Induction of apoptotic DNA fragmentation and cell death by natural ceramide

    Li Ji;Gu Zhang;Shogo Uematsu;Yukio Akahori

  • Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

    H. Satoi;H. Tomimoto;R. Ohtani;T. Kitano

  • Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism.

    Bhagirath Chaurasia;Vincent Andre Kaddai;Graeme Iain Lancaster;Darren C. Henstridge

  • Rapid and specific reactive oxygen species generation via NADPH oxidase activation during Fas-mediated apoptosis.

    Yoshihiro Suzuki;Yasushi Ono;Yoshio Hirabayashi

  • Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart

    Jin Endo;Motoaki Sano;Takaharu Katayama;Takako Hishiki

  • A mouse B16 melanoma mutant deficient in glycolipids

    Shinichi Ichikawa;Nobushige Nakajo;Hisako Sakiyama;Yoshio Hirabayashi

  • A Lipid-Specific Toxin Reveals Heterogeneity of Sphingomyelin-Containing Membranes

    Reiko Ishitsuka;Akiko Yamaji-Hasegawa;Asami Makino;Yoshio Hirabayashi

  • Close association of Guillain–Barré syndrome with antibodies to minor monosialogangliosides GM1b and GM1α

    Nobuhiro Yuki;Nobuhiro Yuki;Yumi Tagawa;Yumi Tagawa;Fumitoshi Irie;Yoshio Hirabayashi

  • A role for ceramide in driving cancer cell resistance to doxorubicin

    Yong-Yu Liu;Jing Yuan Yu;Dongmei Yin;Gauri Anand Patwardhan

  • Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex.

    Hein Sprong;Sophie Degroote;Tijs Claessens;Judith van Drunen

  • Sensitive enzyme-immunostaining and densitometric determination on thin-layer chromatography of N-glycolylneuraminic acid-containing glycosphingolipids, Hanganutziu-Deicher antigens.

    Hideyoshi Higashi;Yukio Fukui;Shigeharu Ueda;Shiro Kato

  • Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.

    Saar Vandekeere;Saar Vandekeere;Charlotte Dubois;Joanna Kalucka;Mark R. Sullivan

  • New insights on glucosylated lipids: Metabolism and functions

    Yohei Ishibashi;Ayako Kohyama-Koganeya;Yoshio Hirabayashi

  • Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality.

    Kazuyuki Yoshida;Shigeki Furuya;Soh Osuka;Junya Mitoma

  • Identification and characterization of human ethanolaminephosphotransferase1.

    Yasuhiro Horibata;Yoshio Hirabayashi

Frequent Co-Authors

Tsutomu Hashikawa
Tsutomu Hashikawa RIKEN Center for Brain Science
Toshihide Kobayashi
Toshihide Kobayashi University of Strasbourg
Yasuo Suzuki
Yasuo Suzuki Chubu University
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Toshiaki Katada
Toshiaki Katada Musashino University
Masaki Yanagishita
Masaki Yanagishita Tokyo Medical and Dental University
Yoshikazu Uchida
Yoshikazu Uchida University of California, San Francisco
Shigeyoshi Itohara
Shigeyoshi Itohara RIKEN Center for Brain Science

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