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Chemistry

D-Index
48
Citations
9751
World Ranking
15120
National Ranking
2345

Overview

Jianhua Ju is affiliated with the Chinese Academy of Sciences in China. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. They have published extensively in several subfields, including pharmacology, molecular biology, biotechnology, organic chemistry, and infectious diseases.

The core topics covered in Jianhua Ju's work involve microbial natural products and biosynthesis, marine sponges and natural products, chemical synthesis and analysis, fungal biology and applications, plant biochemistry and biosynthesis, synthetic organic chemistry methods, and carbohydrate chemistry and synthesis.

Jianhua Ju has contributed to numerous papers, including:

  • "Chlorinated bis-indole alkaloids from deep-sea derived Streptomyces sp. SCSIO 11791 with antibacterial and cytotoxic activities," 2020, The Journal of Antibiotics
  • "Antitubercular Ilamycins from Marine-Derived Streptomyces atratus SCSIO ZH16 ΔilaR," 2020, Journal of Natural Products
  • "Lynamicin B is a Potential Pesticide by Acting as a Lepidoptera-Exclusive Chitinase Inhibitor," 2021, Journal of Agricultural and Food Chemistry
  • "Upregulation of a marine fungal biosynthetic gene cluster by an endobacterial symbiont," 2020, Communications Biology
  • "Julichrome Monomers from Marine Gastropod Mollusk-Associated Streptomyces and Stereochemical Revision of Julichromes Q3 ⋅ 5 and Q3 ⋅ 3," 2020, Chemistry & Biodiversity

Jianhua Ju's frequent coauthors include:

  • Junying Ma
  • Qinglian Li
  • Changli Sun
  • Jiafan Yang
  • Yongxiang Song

Several journals frequently feature Jianhua Ju's research. These include:

  • Journal of Natural Products
  • Marine Drugs
  • Organic Letters
  • ACS Catalysis
  • The Journal of Antibiotics

The breadth of Jianhua Ju's scientific contributions spans over 100 publications in biochemistry, genetics, molecular biology, and related medical sciences. Their work integrates natural product chemistry with applied pharmacology and biotechnology, often using marine-derived organisms as a source for novel chemical compounds and biosynthetic pathways. These research efforts have been documented in peer-reviewed journals with emphasis on antibiotic, antifungal, and pesticidal compounds derived from microbial sources.

Best Publications

  • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

    Tilman Schneider-Poetsch;Jianhua Ju;Daniel E Eyler;Yongjun Dang

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

    Ute Galm;Martin H. Hager;Steven G. Van Lanen;Jianhua Ju

  • Antimalarial β-Carboline and Indolactam Alkaloids from Marinactinospora thermotolerans, a Deep Sea Isolate

    Hongbo Huang;Yueliang Yao;Zhengxiang He;Tingting Yang

  • N-N-Coupled Indolo-sesquiterpene Atropo-Diastereomers from a Marine-Derived Actinomycete

    Qingbo Zhang;Attila Mándi;Sumei Li;Yuchan Chen

  • Naturally occurring tetramic acid products: isolation, structure elucidation and biological activity

    Xuhua Mo;Xuhua Mo;Qinglian Li;Jianhua Ju

  • Spiroindimicins A–D: New Bisindole Alkaloids from a Deep-Sea-Derived Actinomycete

    Wenjun Zhang;Zhong Liu;Sumei Li;Tingting Yang

  • Azaphilones and p-terphenyls from the mangrove endophytic fungus Penicillium chermesinum (ZH4-E2) isolated from the South China Sea.

    Hongbo Huang;Xiaojun Feng;Ze'en Xiao;Lan Liu

  • Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents.

    Junying Ma;Hongbo Huang;Yunchang Xie;Zhiyong Liu

  • A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

    Jian Zhang;Steven G. Van Lanen;Jianhua Ju;Wen Liu

  • Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652

    Xiao Zhou;Hongbo Huang;Yuchan Chen;Jiaheng Tan

  • Discovery of McbB, an Enzyme Catalyzing the β-Carboline Skeleton Construction in the Marinacarboline Biosynthetic Pathway

    Qi Chen;Changtao Ji;Yongxiang Song;Hongbo Huang

  • Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogues and Revealing a Tailoring Dihalogenase

    Yi Xiao;Sumei Li;Siwen Niu;Liang Ma

  • Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria

    Yongxiang Song;Qinglian Li;Xue Liu;Yuchan Chen

  • Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127

    Siwen Niu;Sumei Li;Yuchan Chen;Xinpeng Tian

  • Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps.

    Junying Ma;Zhongwen Wang;Hongbo Huang;Minghe Luo

  • Oxazolomycin Biosynthesis in Streptomyces albus JA3453 Featuring an “Acyltransferase-less” Type I Polyketide Synthase That Incorporates Two Distinct Extender Units

    Chunhua Zhao;Jane M. Coughlin;Jianhua Ju;Dongqing Zhu

  • Lupus enteritis: clinical characteristics, risk factor for relapse and association with anti-endothelial cell antibody.

    S.-K. Kwok;S.-H. Seo;J.H. Ju;K.-S. Park

  • Pseudonocardians A–C, New Diazaanthraquinone Derivatives from a Deap-Sea Actinomycete Pseudonocardia sp. SCSIO 01299

    Sumei Li;Xinpeng Tian;Siwen Niu;Wenjun Zhang

  • Identification and characterization of xiamycin A and oxiamycin gene cluster reveals an oxidative cyclization strategy tailoring indolosesquiterpene biosynthesis.

    Huixian Li;Qingbo Zhang;Sumei Li;Yiguang Zhu

  • Conversion of (2S)-arginine to (2S,3R)-capreomycidine by VioC and VioD from the viomycin biosynthetic pathway of Streptomyces sp. strain ATCC11861.

    Jianhua Ju;Sarah G. Ozanick;Sarah G. Ozanick;Ben Shen;Michael G. Thomas

  • Signal mimics derived from a metagenomic analysis of the gypsy moth gut microbiota.

    Changhui Guan;Jianhua Ju;Bradley R. Borlee;Lynn L. Williamson

Frequent Co-Authors

Ben Shen
Ben Shen Scripps Research Institute
Yu-Cheng Gu
Yu-Cheng Gu Syngenta (Switzerland)
Wen-Jun Li
Wen-Jun Li Sun Yat-sen University
Wenjun Zhang
Wenjun Zhang University of California, Los Angeles
Wen Liu
Wen Liu Chinese Academy of Sciences
Sheng-Xiong Huang
Sheng-Xiong Huang Chinese Academy of Sciences
Herbert Chen
Herbert Chen University of Alabama at Birmingham
Marnix H. Medema
Marnix H. Medema Wageningen University & Research
Nikos C. Kyrpides
Nikos C. Kyrpides Joint Genome Institute

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