Her main research concerns Cell biology, Cell migration, Cell adhesion, Paxillin and Signal transduction. The concepts of her Cell biology study are interwoven with issues in Dendritic spine and Integrin. In her study, PTK2, Proto-oncogene tyrosine-protein kinase Src, Role of cell adhesions in neural development, Molecular biology and MAPK/ERK pathway is inextricably linked to Myosin light-chain kinase, which falls within the broad field of Cell migration.
Her Cell adhesion research is multidisciplinary, incorporating elements of Endosome, Cytological Techniques, Signalling pathways and Cell movement. Her Paxillin research integrates issues from Golgi apparatus and Cytoplasm. In her study, which falls under the umbrella issue of Signal transduction, Phosphorylation and Urokinase receptor is strongly linked to Kinase.
Cell biology, Cell migration, Molecular biology, Biochemistry and Receptor are her primary areas of study. Her Cell biology study combines topics from a wide range of disciplines, such as Dendritic spine and Cell adhesion. Her Cell adhesion study also includes fields such as
Cell migration is a subfield of Cell that Donna J. Webb studies. Her Molecular biology research incorporates themes from Urokinase receptor, Transforming growth factor beta and Neuron. Her study looks at the relationship between Receptor and fields such as Monoclonal antibody, as well as how they intersect with chemical problems.
The scientist’s investigation covers issues in Cell biology, Cell migration, Biophysics, Myosin and Synapse. Her Cell biology study incorporates themes from Receptor and Leucine zipper. Her Leucine zipper research integrates issues from Signal transduction and Cell adhesion.
Her Cell migration research includes themes of Mechanotransduction, Computational biology and Paxillin. Her Biophysics research is multidisciplinary, incorporating elements of Luminescence, Microfluidics and Channelrhodopsin. Her work carried out in the field of Synapse brings together such families of science as Dendritic spine, Dendritic filopodia, Actin cytoskeleton and Spine.
Her primary scientific interests are in Central nervous system, Cell biology, Blood–brain barrier, Microscopy and Fluorescence-lifetime imaging microscopy. Her study in Central nervous system is interdisciplinary in nature, drawing from both Human brain, Nanotechnology and Cell type. Donna J. Webb has included themes like Tumor progression, Integrin and Immunology in her Cell biology study.
The Blood–brain barrier study combines topics in areas such as Tight junction and Systemic inflammation. Her work deals with themes such as Deconvolution, Dichroic glass, Lens, Resolution and Field of view, which intersect with Microscopy. Her work in Fluorescence-lifetime imaging microscopy tackles topics such as Phosphorylation which are related to areas like Biophysics.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.
Donna J. Webb;Karen Donais;Leanna A. Whitmore;Sheila M. Thomas.
Nature Cell Biology (2004)
Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again.
Donna J. Webb;J. Thomas Parsons;Alan F. Horwitz.
Nature Cell Biology (2002)
Differential Dynamics of α5 Integrin, Paxillin, and α-Actinin during Formation and Disassembly of Adhesions in Migrating Cells
Christina M. Laukaitis;Donna J. Webb;Karen Donais;Alan F. Horwitz.
Journal of Cell Biology (2001)
Cell migration at a glance
Miguel Vicente-Manzanares;Donna J. Webb;A. Rick Horwitz.
Journal of Cell Science (2005)
A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC
Huaye Zhang;Donna J. Webb;Hannelore Asmussen;Shuang Niu.
The Journal of Neuroscience (2005)
Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.
Diem H.D. Nguyen;Andrew D. Catling;Donna J. Webb;Mauricio Sankovic.
Journal of Cell Biology (1999)
Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics
Anjana Nayal;Donna J. Webb;Claire M. Brown;Erik M. Schaefer.
Journal of Cell Biology (2006)
Cortactin promotes cell motility by enhancing lamellipodial persistence.
Nicole S. Bryce;Emily S. Clark;Ja’Mes L. Leysath;Joshua D. Currie.
Current Biology (2005)
Asymmetric focal adhesion disassembly in motile cells.
Joshua A Broussard;Donna J Webb;Irina Kaverina.
Current Opinion in Cell Biology (2008)
Synapse formation is regulated by the signaling adaptor GIT1
Huaye Zhang;Donna J. Webb;Hannelore Asmussen;Alan F. Horwitz.
Journal of Cell Biology (2003)
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