Donna J. Webb

Overview

Best Publications

• FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly.

  Donna J. Webb;Karen Donais;Leanna A. Whitmore;Sheila M. Thomas

  1629
  Citations

• Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again.

  Donna J. Webb;J. Thomas Parsons;Alan F. Horwitz

  1049
  Citations

• Differential Dynamics of α5 Integrin, Paxillin, and α-Actinin during Formation and Disassembly of Adhesions in Migrating Cells

  Christina M. Laukaitis;Donna J. Webb;Karen Donais;Alan F. Horwitz

  640
  Citations

• Cell migration at a glance

  Miguel Vicente-Manzanares;Donna J. Webb;A. Rick Horwitz

  555
  Citations

• Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis

  Begum Erdogan;Donna J. Webb

  517
  Citations

• A GIT1/PIX/Rac/PAK Signaling Module Regulates Spine Morphogenesis and Synapse Formation through MLC

  Huaye Zhang;Donna J Webb;Hannelore Asmussen;Shuang Niu

  502
  Citations

• Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin

  Begum Erdogan;Mingfang Ao;Lauren M. White;Anna L. Means

  482
  Citations

• Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner.

  Diem H.D. Nguyen;Andrew D. Catling;Donna J. Webb;Mauricio Sankovic

  456
  Citations

• Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

  Jacquelyn A. Brown;Virginia Pensabene;Dmitry A. Markov;Vanessa Allwardt

  437
  Citations

• Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics

  Anjana Nayal;Donna J. Webb;Claire M. Brown;Erik M. Schaefer

  384
  Citations

• Cortactin promotes cell motility by enhancing lamellipodial persistence.

  Nicole S. Bryce;Emily S. Clark;Ja’Mes L. Leysath;Joshua D. Currie

  356
  Citations

• Asymmetric focal adhesion disassembly in motile cells.

  Joshua A Broussard;Donna J Webb;Irina Kaverina

  334
  Citations

• Synapse formation is regulated by the signaling adaptor GIT1

  Huaye Zhang;Donna J. Webb;Hannelore Asmussen;Alan F. Horwitz

  295
  Citations

• Spatial mapping of integrin interactions and dynamics during cell migration by Image Correlation Microscopy

  Paul W. Wiseman;Claire M. Brown;Donna J. Webb;Benedict Hebert

  290
  Citations

• GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration.

  Ri-ichiroh Manabe;Mykola Kovalenko;Donna J. Webb;Alan Rick Horwitz

  284
  Citations

• N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

  Adam M. Wegner;Caroline A. Nebhan;Lan Hu;Devi Majumdar

  278
  Citations

• Talin: an emerging focal point of adhesion dynamics.

  Anjana Nayal;Donna J Webb;Alan F Horwitz

  236
  Citations

• Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion.

  D.J. Webb;D.H. Nguyen;S.L. Gonias

  230
  Citations

• Urokinase-type Plasminogen Activator Stimulates the Ras/Extracellular Signal-regulated Kinase (ERK) Signaling Pathway and MCF-7 Cell Migration by a Mechanism That Requires Focal Adhesion Kinase, Src, and Shc RAPID DISSOCIATION OF GRB2/SOS-SHC COMPLEX IS ASSOCIATED WITH THE TRANSIENT PHOSPHORYLATION OF ERK IN UROKINASE-TREATED CELLS

  Diem H.D. Nguyen;Donna J. Webb;Andrew D. Catling;Qian Song

  207
  Citations

• Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells.

  Zhong Ma;Donna J. Webb;Minji Jo;Steven L. Gonias

  188
  Citations