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Molecular Biology

D-Index
70
Citations
18842
World Ranking
1415
National Ranking
5

Overview

Hannu Norppa is affiliated with the Finnish Institute of Occupational Health in Finland. The primary field of research is Materials Science, with a focus on Biomaterials, Materials Chemistry, Health, Toxicology and Mutagenesis, Molecular Biology, and Cancer Research.

The main research topics covered by Norppa include:

  • Nanoparticles: synthesis and applications
  • Advanced Cellulose Research Studies
  • Nanocomposite Films for Food Packaging
  • Electrospun Nanofibers in Biomedical Applications
  • Carcinogens and Genotoxicity Assessment
  • Heavy Metal Exposure and Toxicity
  • Graphene and Nanomaterials Applications

Frequent publication venues for Norppa's work are:

  • Nanomaterials
  • Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  • Nanotoxicology
  • Nature Communications
  • Advanced Science

Notable recent papers include:

  • Genotoxicity and Cytotoxicity of Gold Nanoparticles In Vitro: Role of Surface Functionalization and Particle Size (2020, Nanomaterials)
  • Pulmonary toxicity of synthetic amorphous silica - effects of porosity and copper oxide doping (2020, Nanotoxicology)
  • Biomarkers of nanomaterials hazard from multi-layer data (2022, Nature Communications)
  • Toxicogenomic Profiling of 28 Nanomaterials in Mouse Airways (2021, Advanced Science)
  • Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils (2022, Particle and Fibre Toxicology)

Frequently collaborating co-authors include:

  • Julia Catalán
  • Gerard Vales
  • Satu Suhonen
  • Kukka Aimonen
  • Mira Hartikainen

Best Publications

  • Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

    M. Fenech;M. Kirsch-Volders;A. T. Natarajan;J. Surralles

  • IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans

    Richard J Albertini;Diana Anderson;George R Douglas;Lars Hagmar

  • Report from the in vitro micronucleus assay working group

    Micheline Kirsch-Volders;Toshio Sofuni;Marilyn Aardema;Silvio Albertini

  • Chromosomal aberrations in lymphocytes predict human cancer: A report from the European study group on cytogenetic biomarkers and health (ESCH)

    L Hagmar;S Bonassi;U Strömberg;A Brøgger

  • What do human micronuclei contain

    Hannu Norppa;Ghita C.-M. Falck

  • Induction of micronuclei by five pyrethroid insecticides in whole-blood and isolated human lymphocyte cultures.

    J. Surrallés;N. Xamena;A. Creus;J. Catalán

  • Chromosomal aberrations and SCEs as biomarkers of cancer risk

    H. Norppa;S. Bonassi;I-L. Hansteen;L. Hagmar

  • Cytogenetic biomarkers and genetic polymorphisms.

    Hannu Norppa

  • Impact of types of lymphocyte chromosomal aberrations on human cancer risk: results from Nordic and Italian cohorts.

    Lars Hagmar;Ulf Strömberg;Stefano Bonassi;Inger Lise Hansteen

  • Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro.

    Hanna K. Lindberg;Ghita C.-M. Falck;Satu Suhonen;Minnamari Vippola;Minnamari Vippola

  • Report from the in vitro micronucleus assay working group

    M. Kirsch-Volders;T. Sofuni;M. Aardema;S. Albertini

  • Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA

    Pavel Vodicka;Rajiv Kumar;Rajiv Kumar;Rudolf Stetina;Somali Sanyal

  • Chromosomal aberrations and risk of cancer in humans: an epidemiologic perspective

    Stefano Bonassi;Ariana Znaor;Hannu Norppa;L Hagmar

  • Origin of nuclear buds and micronuclei in normal and folate-deprived human lymphocytes

    Hanna K. Lindberg;Xu Wang;Xu Wang;Hilkka Järventaus;Ghita C.-M. Falck

  • Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers.

    Ghita C.-M Falck;Ari Hirvonen;Roberto Scarpato;Sirkku T Saarikoski

  • Chromosomal Aberrations and Cancer Risk: Results of a Cohort Study from Central Europe

    Paolo Boffetta;Olga van der Hel;Hannu Norppa;Eleonora Fabianova

  • The Effects of GSTM1 and GSTT1 Polymorphisms on Micronucleus Frequencies in Human Lymphocytes In vivo

    Micheline Kirsch-Volders;Raluca Antonina Mateuca;Mathieu Roelants;Annie Tremp

  • Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes.

    H Norppa;A Hirvonen;H Järventaus;M Uusküla

  • Increased sister chromatid exchange frequencies in lymphocytes of nurses handling cytostatic drugs.

    Hannu Norppa;Marja Sorsa;Harri Vainio;Pentti Gröhn

  • Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity

    Jarno Tuimala;Gabor Szekely;Sarolta Gundy;Ari Hirvonen

Frequent Co-Authors

Ari Hirvonen
Ari Hirvonen Finnish Institute of Occupational Health
Harri Vainio
Harri Vainio Kuwait University
Harri Alenius
Harri Alenius Karolinska Institute
Stefano Bonassi
Stefano Bonassi San Raffaele University of Rome
Jordi Surrallés
Jordi Surrallés Autonomous University of Barcelona
Roberto Barale
Roberto Barale University of Pisa
Lars Hagmar
Lars Hagmar Lund University
Michael Fenech
Michael Fenech University of South Australia
Lucia Migliore
Lucia Migliore University of Pisa
Micheline Kirsch-Volders
Micheline Kirsch-Volders Vrije Universiteit Brussel

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