D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 10,375 181 World Ranking 11542 National Ranking 4959

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Enzyme

Her main research concerns Immunology, Immunotherapy, Chimeric antigen receptor, Cancer research and CD8. Her study looks at the intersection of Chimeric antigen receptor and topics like Cytotoxic T cell with T cell. Christine E. Brown has researched Cancer research in several fields, including Chimeric Antigen Receptor T-Cell Therapy, CTL* and Antigen.

Christine E. Brown combines subjects such as Interleukin, Interleukin 13, Cancer and Adoptive cell transfer with her study of CTL*. Her Antigen research is multidisciplinary, relying on both Cell culture, Alpha-2 adrenergic receptor, Cerebrospinal fluid, Cellular differentiation and Immune system. Her work deals with themes such as Hematopoietic stem cell transplantation, Internal medicine, Transplantation, Oncology and B cell, which intersect with CD8.

Her most cited work include:

  • Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy (649 citations)
  • The many HATs of transcription coactivators. (311 citations)
  • Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma (311 citations)

What are the main themes of her work throughout her whole career to date?

Her primary scientific interests are in Chimeric antigen receptor, Cancer research, T cell, Immunotherapy and Immunology. Her biological study spans a wide range of topics, including Receptor, Cell, Antibody and Molecular biology. The various areas that Christine E. Brown examines in her Cancer research study include Car t cells, Immune system and Antigen.

Her T cell research includes elements of B cell and Cell biology. Her study in Immunotherapy is interdisciplinary in nature, drawing from both Leukemia, Myeloid leukemia, Oncology and Lymphoma. Within one scientific family, Christine E. Brown focuses on topics pertaining to Cytotoxic T cell under Immunology, and may sometimes address concerns connected to Priming.

She most often published in these fields:

  • Chimeric antigen receptor (54.71%)
  • Cancer research (52.94%)
  • T cell (28.82%)

What were the highlights of her more recent work (between 2018-2021)?

  • Chimeric antigen receptor (54.71%)
  • Cancer research (52.94%)
  • Antigen (24.71%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Chimeric antigen receptor, Cancer research, Antigen, Immunotherapy and T cell. Chimeric antigen receptor is a subfield of Cancer that Christine E. Brown explores. Her Cancer research study incorporates themes from Cancer cell, Cancer immunotherapy, Immune system and Effector.

Her studies deal with areas such as Cell, Central nervous system, Chlorotoxin, Chimeric Antigen Receptor T-Cell Therapy and Lymphoma as well as Antigen. Her studies in Immunotherapy integrate themes in fields like Cytotoxic T cell, Glioblastoma and Oncology. Her T cell study integrates concerns from other disciplines, such as Solid tumor, Biophysics and Cell biology.

Between 2018 and 2021, her most popular works were:

  • CAR T cell therapy: inroads to response and resistance (71 citations)
  • IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype (61 citations)
  • CAR T cells for brain tumors: Lessons learned and road ahead. (47 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

Christine E. Brown mainly investigates Chimeric antigen receptor, Cancer research, Immunotherapy, Antigen and Cell. She has included themes like Stem cell and B cell in her Chimeric antigen receptor study. Christine E. Brown interconnects Receptor and Lymphoma in the investigation of issues within B cell.

Her research in Cancer research intersects with topics in Adoptive cell transfer and Effector. The Adoptive cell transfer study combines topics in areas such as CD8, Chlorotoxin, Peptide, Matrix and In vivo. Her Immunotherapy research integrates issues from T cell, Antibody, Blocking antibody and Cerebrospinal fluid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Brown Ce;Alizadeh D;Starr R;Weng L.
The New England Journal of Medicine (2016)

1156 Citations

Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma

Christine E. Brown;Behnam Badie;Michael E. Barish;Lihong Weng.
Clinical Cancer Research (2015)

515 Citations

The many HATs of transcription coactivators.

Christine E Brown;Thomas Lechner;LeAnn Howe;Jerry L Workman.
Trends in Biochemical Sciences (2000)

478 Citations

Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit.

Christine E. Brown;LeAnn Howe;Kyle Sousa;Stephen C. Alley.
Science (2001)

413 Citations

Specific Recognition and Killing of Glioblastoma Multiforme by Interleukin 13-Zetakine Redirected Cytolytic T Cells

Kanwarpal S. Kahlon;Christine Brown;Laurence J. N. Cooper;Andrew Raubitschek.
Cancer Research (2004)

385 Citations

Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

Christine E. Brown;Alan B. Sachs.
Molecular and Cellular Biology (1998)

362 Citations

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Armen Mardiros;Cedric Dos Santos;Tinisha McDonald;Christine E. Brown.
Blood (2013)

353 Citations

Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL

Xiuli Wang;Leslie L. Popplewell;Jamie R. Wagner;Araceli Naranjo.
Blood (2016)

252 Citations

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies.

Karen S. Aboody;Joseph Najbauer;Marianne Z. Metz;Massimo D’Apuzzo.
Science Translational Medicine (2013)

238 Citations

PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae.

Christine E. Brown;Salvador Z. Tarun;Ronald Boeck;Andalan B. Sachs.
Molecular and Cellular Biology (1996)

223 Citations

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