Christine E. Brown

Overview

Best Publications

• Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

  Brown Ce;Alizadeh D;Starr R;Weng L

  1846
  Citations

• Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma

  Christine E. Brown;Behnam Badie;Michael E. Barish;Lihong Weng

  712
  Citations

• The many HATs of transcription coactivators.

  Christine E Brown;Thomas Lechner;LeAnn Howe;Jerry L Workman

  495
  Citations

• Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit.

  Christine E. Brown;LeAnn Howe;Kyle Sousa;Stephen C. Alley

  449
  Citations

• T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

  Armen Mardiros;Cedric Dos Santos;Tinisha McDonald;Christine E. Brown

  437
  Citations

• Specific Recognition and Killing of Glioblastoma Multiforme by Interleukin 13-Zetakine Redirected Cytolytic T Cells

  Kanwarpal S. Kahlon;Christine Brown;Laurence J. N. Cooper;Andrew Raubitschek

  421
  Citations

• Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

  Christine E. Brown;Alan B. Sachs

  372
  Citations

• IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype

  Darya Alizadeh;Robyn A. Wong;Xin Yang;Dongrui Wang

  324
  Citations

• Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL

  Xiuli Wang;Leslie L. Popplewell;Jamie R. Wagner;Araceli Naranjo

  316
  Citations

• Regional Delivery of Chimeric Antigen Receptor–Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain

  Saul J. Priceman;Dileshni Tilakawardane;Brook Jeang;Brenda Aguilar

  313
  Citations

• Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma.

  Khun Visith Keu;Timothy H. Witney;Timothy H. Witney;Shahriar Yaghoubi;Jarrett Rosenberg

  303
  Citations

• Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies.

  Karen S. Aboody;Joseph Najbauer;Marianne Z. Metz;Massimo D’Apuzzo

  276
  Citations

• Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma.

  Christine E. Brown;Brenda Aguilar;Renate Starr;Xin Yang

  248
  Citations

• Stem-like Tumor-Initiating Cells Isolated from IL13Rα2 Expressing Gliomas Are Targeted and Killed by IL13-Zetakine–Redirected T Cells

  Christine E. Brown;Renate Starr;Brenda Aguilar;Andrew F. Shami

  240
  Citations

• PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae.

  Christine E. Brown;Salvador Z. Tarun;Ronald Boeck;Andalan B. Sachs

  231
  Citations

• Transcription Activator Interactions with Multiple SWI/SNF Subunits

  Kristen E. Neely;Ahmed H. Hassan;Christine E. Brown;LeAnn Howe

  229
  Citations

• Targeting Alpha-Fetoprotein (AFP)-MHC Complex with CAR T-Cell Therapy for Liver Cancer.

  Hong Liu;Yiyang Xu;Jingyi Xiang;Li Long

  216
  Citations

• Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications.

  Hamid R. Mirzaei;Analiz Rodriguez;Jennifer Shepphird;Christine E. Brown

  199
  Citations

• Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy

  Mahesh Jonnalagadda;Armen Mardiros;Ryan Urak;Xiuli Wang

  196
  Citations

• Tumor PD-L1 co-stimulates primary human CD8(+) cytotoxic T cells modified to express a PD1:CD28 chimeric receptor.

  Megan E. Prosser;Christine E. Brown;Andrew F. Shami;Stephen J. Forman

  195
  Citations