Member of the European Molecular Biology Organization (EMBO)
Fellow of The Academy of Medical Sciences, United Kingdom
Clare M. Isacke mainly focuses on Cell biology, Molecular biology, Hyaluronan-mediated motility receptor, Biochemistry and Cancer research. Her Cell biology research incorporates elements of Receptor, Transmembrane protein and CD44. Clare M. Isacke has included themes like Epidermal growth factor, Platelet-derived growth factor receptor, Tyrosine phosphorylation, Protein phosphorylation and MAP2K7 in her Molecular biology study.
In her research, Merlin, Contact inhibition and Cell growth is intimately related to Ezrin, which falls under the overarching field of Hyaluronan-mediated motility receptor. Her Cancer research research integrates issues from Endocrinology, Glial cell line-derived neurotrophic factor, Proto-Oncogene Proteins c-ret, Internal medicine and Tumor progression. Her study looks at the relationship between Tumor progression and topics such as Transforming growth factor beta, which overlap with Pathology.
Clare M. Isacke focuses on Cell biology, Cancer research, Molecular biology, Breast cancer and Pathology. Her Cell biology study combines topics from a wide range of disciplines, such as Receptor, Cell migration and Hyaluronan-mediated motility receptor, CD44. Her Cancer research study combines topics in areas such as Cancer, Metastasis, Oncogene and In vivo.
Her research on Molecular biology frequently links to adjacent areas such as Monoclonal antibody. Internal medicine covers Clare M. Isacke research in Breast cancer. Her biological study spans a wide range of topics, including Endocrinology and Oncology.
Cancer research, Breast cancer, Cancer, Internal medicine and Metastasis are her primary areas of study. Her Cancer research study incorporates themes from Oncogene, Estrogen receptor, In vivo and Pathology. The various areas that Clare M. Isacke examines in her Breast cancer study include Leptomeningeal metastasis, Proto-Oncogene Proteins c-ret, Outpatient clinic and Surgical oncology.
Her Cancer research is multidisciplinary, incorporating perspectives in Phenotype, Cell culture, RNA interference and Immunology. Her research integrates issues of Endocrinology and Oncology in her study of Internal medicine. Her work in Cell biology addresses issues such as Cell, which are connected to fields such as Metastasis Suppressor Gene.
Clare M. Isacke spends much of her time researching Cancer research, Breast cancer, Metastasis, Cell biology and In vivo. Her studies deal with areas such as Cancer, Suppressor, Fibrosis, Pathology and RNA interference as well as Cancer research. Her work carried out in the field of Pathology brings together such families of science as Matrix metalloproteinase and Epigenetics.
The study incorporates disciplines such as Epithelial–mesenchymal transition and DNA methylation in addition to Breast cancer. Her Cell biology study focuses on Progenitor cell in particular. She interconnects CD44, Beta oxidation, Aldo-keto reductase, Metastatic breast cancer and Transfection in the investigation of issues within In vivo.
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The mannose receptor family.
Lucy East;Clare M Isacke.
Biochimica et Biophysica Acta (2002)
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
Helen Morrison;Larry S. Sherman;James Legg;Fatima Banine.
Genes & Development (2001)
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus
Lisa Coussens;Charles Van Beveren;Douglas Smith;Ellson Chen.
CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
Katherine E. Sleeman;Howard Kendrick;Alan Ashworth;Clare M. Isacke.
Breast Cancer Research (2005)
Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland.
Katherine E. Sleeman;Howard Kendrick;David Robertson;Clare M. Isacke.
Journal of Cell Biology (2007)
A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility.
James W. Legg;Charlotte A. Lewis;Maddy Parsons;Tony Ng.
Nature Cell Biology (2002)
The hyaluronan receptor, CD44.
Clare M. Isacke;Helen Yarwood.
The International Journal of Biochemistry & Cell Biology (2002)
The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events
Rick F. Thorne;James W. Legg;Clare M. Isacke.
Journal of Cell Science (2003)
A HaemAtlas: Characterizing gene expression in differentiated human blood cells
Nicholas A. Watkins;Arief Gusnanto;Bernard de Bono;Subhajyoti De.
Identification and functional analysis of the ezrin-binding site in the hyaluronan receptor, CD44
James W. Legg;Clare M. Isacke.
Current Biology (1998)
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