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Overview

Keping Xie is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research output spans primarily the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on several subfields including Molecular Biology, Oncology, Cancer Research, Immunology, and Surgery.

Their work addresses multiple key research areas, particularly:

  • Pancreatic and Hepatic Oncology Research
  • Cancer Immunotherapy and Biomarkers
  • Epigenetics and DNA Methylation
  • Pancreatic function and diabetes
  • MicroRNA in disease regulation
  • Cancer-related gene regulation
  • FOXO transcription factor regulation

Among the recent papers associated with Keping Xie are:

  • "Therapeutic resistance of pancreatic cancer: Roadmap to its reversal," 2020, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • "KLF4 transcription factor in tumorigenesis," 2023, Cell Death Discovery
  • "Coupled liquid biopsy and bioinformatics for pancreatic cancer early detection and precision prognostication," 2021, Molecular Cancer
  • "Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to Therapeutics," 2020, Cancer Research
  • "Anticoagulants Enhance Molecular and Cellular Immunotherapy of Cancer by Improving Tumor Microcirculation Structure and Function and Redistributing Tumor Infiltrates," 2023, Clinical Cancer Research

Keping Xie frequently collaborates with several researchers, including:

  • Xiaojia Li (13 collaborations)
  • Jie He (10 collaborations)
  • Qi Zou (7 collaborations)
  • Wei Fang (6 collaborations)
  • Tingting Jiang (6 collaborations)

Their publications often appear in the following venues:

  • Genes & Diseases (6 publications)
  • International Journal of Biological Sciences (3 publications)
  • Molecular Carcinogenesis (3 publications)
  • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer (2 publications)
  • Clinical Cancer Research (2 publications)

Best Publications

  • m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.

    Sicong Zhang;Boxuan Simen Zhao;Aidong Zhou;Kangyu Lin

  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis

    Daoyan Wei;Xiangdong Le;Leizhen Zheng;Liwei Wang

  • FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

    Nu Zhang;Nu Zhang;Ping Wei;Ping Wei;Aihua Gong;Wen Tai Chiu

  • Activation of stat3 in human melanoma promotes brain metastasis.

    Tongxin Xie;Feng Ju Huang;Feng Ju Huang;Kenneth D. Aldape;Shin Hyuk Kang

  • Transcription Factor Sp1 Expression Is a Significant Predictor of Survival in Human Gastric Cancer

    Liwei Wang;Daoyan Wei;Suyun Huang;Zhihai Peng

  • FoxM1B Is Overexpressed in Human Glioblastomas and Critically Regulates the Tumorigenicity of Glioma Cells

    Mingguang Liu;Bingbing Dai;Shin Hyuk Kang;Kechen Ban

  • Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells

    Keping Xie;Suyun Huang;Zhongyun Dong;Shin Hun Juang

  • Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma.

    Qian Shi;Xiangdong Le;James L. Abbruzzese;Zhihai Peng

  • Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression.

    Daoyan Wei;Weida Gong;Masashi Kanai;Christian Schlunk

  • Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.

    Qian Shi;James L. Abbruzzese;Suyun Huang;Isaiah J. Fidler

  • Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity.

    Daoyan Wei;Liwei Wang;Yanjuan He;Henry Q. Xiong

  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells

    Qian Shi;Xiangdong Le;Bailiang Wang;James L. Abbruzzese

  • Emerging role of KLF4 in human gastrointestinal cancer.

    Daoyan Wei;Masashi Kanai;Suyun Huang;Keping Xie

  • Therapy of cancer metastasis by activation of the inducible nitric oxide synthase.

    Keping Xie;Isaiah J. Fidler

  • Inverse Correlation between Expression of Inducible Nitric Oxide Synthase Activity and Production of Metastasis in K-1735 Murine Melanoma Cells

    Zhongyun Dong;Alexander H. Staroselsky;Xiaoxia Qi;Keping Xie

  • Association between Expression of Transcription Factor Sp1 and Increased Vascular Endothelial Growth Factor Expression, Advanced Stage, and Poor Survival in Patients with Resected Gastric Cancer

    James C Yao;Liwei Wang;Daoyan Wei;Weida Gong

  • FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression

    Jiujie Cui;Min Shi;Dacheng Xie;Daoyan Wei

  • Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.

    Yoshito Akagi;Wenbiao Liu;Brian Zebrowski;Keping Xie

  • Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression.

    Qiang Li;Nu Zhang;Zhiliang Jia;Xiangdong Le

  • Elevated expression of vascular endothelial growth factor correlates with increased angiogenesis and decreased progression-free survival among patients with low-grade neuroendocrine tumors

    Jun Zhang;Zhiliang Jia;Qiang Li;Liwei Wang

Frequent Co-Authors

Suyun Huang
Suyun Huang Virginia Commonwealth University
James C. Yao
James C. Yao The University of Texas MD Anderson Cancer Center
Isaiah J. Fidler
Isaiah J. Fidler The University of Texas MD Anderson Cancer Center
James L. Abbruzzese
James L. Abbruzzese Duke University
Jaffer A. Ajani
Jaffer A. Ajani The University of Texas MD Anderson Cancer Center
Raymond Sawaya
Raymond Sawaya The University of Texas MD Anderson Cancer Center
Jun Yao
Jun Yao The University of Texas MD Anderson Cancer Center
Corazon D. Bucana
Corazon D. Bucana The University of Texas MD Anderson Cancer Center
Tsung Teh Wu
Tsung Teh Wu Mayo Clinic
Paul F. Mansfield
Paul F. Mansfield The University of Texas MD Anderson Cancer Center

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