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Stellan Sandler

Stellan Sandler

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
6427
World Ranking
19315
National Ranking
308

Overview

Stellan Sandler is a researcher affiliated with Uppsala University in Sweden with a focus on immunology, molecular biology, and related biomedical fields. Their work encompasses immunology and microbiology, with particular emphasis on diabetes and associated disorders, T-cell and B-cell immunology, and immune cell function and interaction. Sandler's research also touches on proteoglycans and glycosaminoglycans, glycosylation and glycoproteins, and fibroblast growth factor studies.

Their publication record includes several recent papers covering key topics within immunological responses and autoimmune diabetes. Notable papers authored or co-authored by Sandler include:

  • Significance of host heparanase in promoting tumor growth and metastasis, 2020, published in Matrix Biology
  • Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells, 2021, International Journal of Molecular Sciences
  • Assessing the effectiveness of Interleukin-2 therapy in experimental type 1 diabetes, 2024, Endocrine
  • IL-35 producing antigen presenting cells in type 1 diabetes, 2020, The Journal of Immunology
  • Anti-IL-6R prevents experimental type 1 diabetes, 2023, The Journal of Immunology

The typical publication venues for Sandler include The Journal of Immunology, Matrix Biology, International Journal of Molecular Sciences, and Endocrine.

Frequent collaborators in their research include K. N. Singh, Zhengkang Luo, Martin Blixt, Daniel Espes, and Mariela Mejia-Cordova, reflecting a multidisciplinary and collaborative research environment.

Main fields of study associated with Sandler's work are:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields within these broader areas include:

  • Immunology
  • Genetics
  • Molecular Biology
  • Cell Biology

The primary topics Sandler addresses in research are:

  • Diabetes and associated disorders
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Proteoglycans and glycosaminoglycans research
  • Glycosylation and Glycoproteins Research
  • Fibroblast Growth Factor Research

Best Publications

  • Interleukin-lβ-Induced Nitric Oxide Production in Isolated Rat Pancreatic Islets Requires Gene Transcription and May Lead to Inhibition of the Krebs Cycle Enzyme Aconitase

    Nils Welsh;Decio L. Eizirik;Klaus Bendtzen;Stellan Sandler

  • Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.

    Décio L. Eizirik;Stellan Sandler;Nils Welsh;Marina Cetkovic-Cvrlje

  • Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets.

    Stellan Sandler;Arne Andersson;Claes Hellerström

  • Interleukin-6 Affects Insulin Secretion and Glucose Metabolism of Rat Pancreatic Islets in Vitro

    Stellan Sandler;Klaus Bendtzen;Décio L. Eizirik;Michael Welsh

  • Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

    J. Størling;J. Binzer;A. K. Andersson;R. A. Züllig

  • The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules.

    Aileen King;Stellan Sandler;Arne Andersson

  • Glucose- and Hormone-Induced cAMP Oscillations in α- and β-Cells Within Intact Pancreatic Islets

    Geng Tian;Stellan Sandler;Erik Gylfe;Anders Tengholm

  • The gastric mucus layers: constituents and regulation of accumulation

    Mia Phillipson;Malin E. V. Johansson;Johanna Henriksnäs;Joel Petersson

  • Large-scale production of fetal porcine pancreatic isletlike cell clusters. An experimental tool for studies of islet cell differentiation and xenotransplantation.

    Olle Korsgren;Stellan Sandler;Annika Schnell Landström;Leif Jansson

  • Islet loss and alpha cell expansion in type 1 diabetes induced by multiple low-dose streptozotocin administration in mice.

    Z Li;FA Karlsson;S Sandler

  • Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.

    Robert Hägerkvist;Stellan Sandler;Dariush Mokhtari;Nils Welsh

  • Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1 beta indicate a perturbation in the mitochondrial function.

    S Sandler;K Bendtzen;L A Borg;Decio L. Eizirik

  • IL-1 receptor antagonist inhibits recurrence of disease after syngeneic pancreatic islet transplantation to spontaneously diabetic non-obese diabetic (NOD) mice

    J O Sandberg;Decio L. Eizirik;S Sandler

  • Biochemical and molecular actions of interleukin-1 on pancreatic beta-cells.

    Stellan Sandler;Décio L. Eizirik;Carina Svensson;Eva Strandell

  • Interleukin-1β induces nitric oxide production and inhibits the activity of aconitase without decreasing glucose oxidation rates in isolated mouse pancreatic islets

    Nils Welsh;Stellan Sandler

  • Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets.

    L A Borg;E Cagliero;S Sandler;Nils Welsh

  • Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background.

    O Korsgren;L Jansson;S Sandler;A Andersson

  • Liposomal Delivery of Purified Heat Shock Protein hsp70 Into Rat Pancreatic Islets as Protection Against Interleukin 1β–Induced Impaired β-Cell Function

    Boris A Margulis;Stellan Sandler;Décio L Eizirik;Nils Welsh

  • Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice.

    Kailash Singh;Marcus Hjort;Lina Thorvaldson;Stellan Sandler

  • An interleukin-1 receptor antagonist protein protects insulin-producing beta cells against suppressive effects of interleukin-1 beta.

    Decio L. Eizirik;D E Tracey;K Bendtzen;S Sandler

Frequent Co-Authors

Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Claes Hellerström
Claes Hellerström Uppsala University
Klaus Bendtzen
Klaus Bendtzen Rigshospitalet
Michael Welsh
Michael Welsh Uppsala University
Olle Korsgren
Olle Korsgren Uppsala University
Anders Hallberg
Anders Hallberg Uppsala University
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Israel Vlodavsky
Israel Vlodavsky Technion – Israel Institute of Technology
Jin-Ping Li
Jin-Ping Li Uppsala University
Leena Peltonen
Leena Peltonen University of Helsinki

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