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Chemistry

D-Index
46
Citations
8290
World Ranking
15988
National Ranking
3992

Overview

Daniel L. Minor is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications spanning 69 works in this domain. Within molecular biology, a subfield with 66 publications, Minor's research intersects with cardiology and cardiovascular medicine, environmental chemistry, cellular and molecular neuroscience, and organic chemistry.

Minor's main research topics include:

  • Ion channel regulation and function
  • Nicotinic acetylcholine receptors study
  • Cardiac electrophysiology and arrhythmias
  • Marine toxins and detection methods
  • Neuroscience and neuropharmacology research
  • Ion channels and receptors
  • Lipid membrane structure and behavior

They have contributed to numerous publications in a range of prominent venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory), with 11 publications
  • Biophysical Journal, with 9 publications
  • Nature Structural & Molecular Biology, with 4 publications
  • IUPHAR/BPS Guide to Pharmacology CITE, with 4 publications
  • Journal of Molecular Biology, with 3 publications

Among Minor's recent scientific papers are:

  • "K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions," 2020, Science Advances
  • "Structural Insights into the Mechanisms and Pharmacology of K2P Potassium Channels," 2021, Journal of Molecular Biology
  • "EMC chaperone-CaV structure reveals an ion channel assembly intermediate," 2023, Nature
  • "Polynuclear Ruthenium Amines Inhibit K2P Channels via a "Finger in the Dam" Mechanism," 2020, Cell Chemical Biology
  • "Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins," 2021, The Journal of General Physiology

Major frequent co-authors engaged in collaborative work with Minor include:

  • Zhou Chen
  • Fayal Abderemane-Ali
  • J. Du Bois
  • Michael Grabe
  • Marco Lolicato

Best Publications

  • Measurement of the beta-sheet-forming propensities of amino acids.

    Daniel L. Minor;Peter S. Kim

  • Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain

    Filip Van Petegem;Kimberly A. Clark;Franck C. Chatelain;Daniel L. Minor

  • Identification of D-peptide ligands through mirror-image phage display

    Ton N. M. Schumacher;Lorenz M. Mayr;Daniel L. Minor;Michael A. Milhollen

  • Context-dependent secondary structure formation of a designed protein sequence

    Daniel L. Minor;Peter S. Kim

  • Context is a major determinant of beta-sheet propensity.

    Daniel L. Minor;Peter S. Kim

  • Cryo-EM structures of the TMEM16A calcium-activated chloride channel.

    Shangyu Dang;Shengjie Feng;Jason Tien;Christian Joseph Peters

  • The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.

    Helen Walden;Michael S Podgorski;Danny T Huang;David W Miller

  • Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex.

    Filip Van Petegem;Franck C Chatelain;Daniel L Minor

  • The Polar T1 Interface Is Linked to Conformational Changes that Open the Voltage-Gated Potassium Channel

    Daniel L. Minor;Yu Fung Lin;Bret C. Mobley;Abigail Avelar

  • K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site

    Marco Lolicato;Cristina Arrigoni;Takahiro Mori;Yoko Sekioka

  • Three-dimensional structure of the KChIP1–Kv4.3 T1 complex reveals a cross-shaped octamer

    Marta Pioletti;Felix Findeisen;Greg L Hura;Daniel L Minor

  • Transmembrane structure of an inwardly rectifying potassium channel.

    Daniel L Minor;Susan J Masseling;Yuh Nung Jan;Lily Yeh Jan

  • Coiled Coils Direct Assembly of a Cold-Activated TRP Channel

    Pamela R. Tsuruda;David Julius;Daniel L. Minor

  • Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.

    David Shaya;Felix Findeisen;Fayal Abderemane-Ali;Fayal Abderemane-Ali;Fayal Abderemane-Ali;Cristina Arrigoni

  • Chemical informatics and target identification in a zebrafish phenotypic screen

    Christian Laggner;David Kokel;David Kokel;Vincent Setola;Alexandra Tolia

  • Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.

    Marco Lolicato;Paul M. Riegelhaupt;Cristina Arrigoni;Kimberly A. Clark

  • X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coil

    Yuichiro Fujiwara;Daniel L. Minor

  • Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation.

    Eun Young Kim;Christine H. Rumpf;Yuichiro Fujiwara;Elizabeth S. Cooley

  • A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels.

    Sviatoslav N. Bagriantsev;Kean-Hooi Ang;Alejandra Gallardo-Godoy;Kimberly A. Clark

  • Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins.

    David Shaya;Mohamed Kreir;Rebecca A. Robbins;Stephanie Wong

Frequent Co-Authors

Ehud Y. Isacoff
Ehud Y. Isacoff University of California, Berkeley
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Gábor Á. Czirják
Gábor Á. Czirják Leibniz Association
Florian Lesage
Florian Lesage Centre national de la recherche scientifique, CNRS
J. Du Bois
J. Du Bois Stanford University
Charles S. Craik
Charles S. Craik University of California, San Francisco
Eric Honoré
Eric Honoré Grenoble Alpes University
Boris Martinac
Boris Martinac Victor Chang Cardiac Research Institute
William F. DeGrado
William F. DeGrado University of California, San Francisco

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