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D-Index & Metrics

Chemistry

D-Index
59
Citations
14187
World Ranking
10052
National Ranking
2798

Research.com Recognitions

  • 2004 - Fellow of Alfred P. Sloan Foundation

Overview

J. Du Bois is affiliated with Stanford University in the United States and has a research focus primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Their work extensively covers Molecular Biology and Cellular and Molecular Neuroscience, with additional contributions to Environmental Chemistry, Organic Chemistry, and Cardiology and Cardiovascular Medicine.

The scientist's research topics include the regulation and function of ion channels, studies of nicotinic acetylcholine receptors, neuroscience and neuropharmacology, marine toxins and detection methods, cardiac electrophysiology and arrhythmias, photoreceptor and optogenetics research, as well as catalytic C-H functionalization methods.

Du Bois has published multiple recent papers encompassing several interdisciplinary areas. Selected examples include:

  • "Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on 'toxin sponge' proteins" (2021) in The Journal of General Physiology
  • "Discovery of a selective, state-independent inhibitor of NaV1.7 by modification of guanidinium toxins" (2020) in Scientific Reports
  • "Mechanistic Guidance Leads to Enhanced Site-Selectivity in C-H Oxidation Reactions Catalyzed by Ruthenium bis(Bipyridine) Complexes" (2021) in ACS Catalysis
  • "Veratridine: A Janus-Faced Modulator of Voltage-Gated Sodium Ion Channels" (2020) in ACS Chemical Neuroscience
  • "Electrochemical Ruthenium-Catalyzed C-H Hydroxylation of Amine Derivatives in Aqueous Acid" (2020) in Organic Letters

Frequent coauthors contributing to Du Bois's work include Daniel L. Minor, Holly S. Hajare, Zhou Chen, Sandra Zakrzewska, and Fayal Abderemane-Ali.

Their research outputs have been published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Biophysical Journal, Proceedings of the National Academy of Sciences, and eLife.

Among professional recognitions, J. Du Bois was named a Fellow of the Alfred P. Sloan Foundation in 2004.

Best Publications

  • Metal-catalyzed nitrogen-atom transfer methods for the oxidation of aliphatic C-H bonds.

    Jennifer L. Roizen;Mark Edwin Harvey;J. Du Bois

  • Expanding the scope of C-H amination through catalyst design.

    Christine G. Espino;Kristin Williams Fiori;Mihyong Kim;J. Du Bois

  • Synthesis of 1,3-Difunctionalized Amine Derivatives through Selective C−H Bond Oxidation

    Christine G. Espino;Paul M. Wehn;and Jessica Chow;J. Du Bois

  • A Rh‐Catalyzed C−H Insertion Reaction for the Oxidative Conversion of Carbamates to Oxazolidinones

    Christine G. Espino;J. Du Bois

  • C-H functionalization in organic synthesis.

    Huw M. L. Davies;Justin Du Bois;Jin-Quan Yu

  • Catalytic intermolecular amination of C-H bonds: method development and mechanistic insights.

    Kristin Williams Fiori;J Du Bois

  • A stereoselective synthesis of (-)-tetrodotoxin.

    Andrew Hinman;J. Du Bois

  • A chiral rhodium carboxamidate catalyst for enantioselective C-H amination.

    David N. Zalatan;J. Du Bois

  • Rhodium-Catalyzed C–H Amination. An Enabling Method for Chemical Synthesis

    J. Du Bois

  • Metal-Catalyzed Oxidations of C–H to C–N Bonds

    David N. Zalatan;J. Du Bois

  • Nitridomanganese(V) Complexes: Design, Preparation, and Use as Nitrogen Atom-Transfer Reagents

    J. Du Bois;Craig S. Tomooka;Jason Hong;Erick M. Carreira

  • A mechanistic analysis of the Rh-catalyzed intramolecular C–H amination reaction

    Kristin Williams Fiori;Christine G. Espino;Benjamin H. Brodsky;J. Du Bois

  • A diruthenium catalyst for selective, intramolecular allylic C-H amination: reaction development and mechanistic insight gained through experiment and theory.

    Mark Edwin Harvey;Djamaladdin G. Musaev;J. Du Bois

  • A Unique and Highly Efficient Method for Catalytic Olefin Aziridination

    Kiran Guthikonda;J. Du Bois

  • A synthesis of (+)-saxitoxin.

    James J. Fleming;J. Du Bois

  • Oxaziridine-Mediated Catalytic Hydroxylation of Unactivated 3° C−H Bonds Using Hydrogen Peroxide

    Benjamin H. Brodsky;J. Du Bois

  • Understanding the differential performance of Rh2(esp)2 as a catalyst for C-H amination.

    David N. Zalatan;J. Du Bois

  • Understanding the dioxygen reaction chemistry of diiron proteins through synthetic modeling studies

    J Du Bois;Tadashi J Mizoguchi;Stephen J Lippard

  • Enantioselective synthesis of the bromopyrrole alkaloids manzacidin A and C by stereospecific C-h bond oxidation.

    Paul M. Wehn and;J. Du Bois

  • (+)-saxitoxin : A first and second generation stereoselective synthesis

    James J. Fleming;Matthew D. Mcreynolds;J. Du Bois

Frequent Co-Authors

Matthew S. Sigman
Matthew S. Sigman University of Utah
Barry M. Trost
Barry M. Trost Stanford University
Richard N. Zare
Richard N. Zare Stanford University
Djamaladdin G. Musaev
Djamaladdin G. Musaev Emory University
John R. Huguenard
John R. Huguenard Stanford University
T. Daniel P. Stack
T. Daniel P. Stack Stanford University
Daniel L. Minor
Daniel L. Minor University of California, San Francisco
Brian M. Stoltz
Brian M. Stoltz California Institute of Technology
W. E. Moerner
W. E. Moerner Stanford University

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