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Biology and Biochemistry

D-Index
74
Citations
16753
World Ranking
5711
National Ranking
2705

Overview

David T. Yue was affiliated with Johns Hopkins University School of Medicine in the United States. Their research spanned multiple areas within medicine and biochemistry, genetics, and molecular biology, with a focus on ion channel regulation and function as well as cardiac electrophysiology and arrhythmias.

Their recent publications included the following papers:

  • Elementary mechanisms of calmodulin regulation of Na V 1.5 producing divergent arrhythmogenic phenotypes, 2021, Proceedings of the National Academy of Sciences
  • The molecular basis of the inhibition of CaV1 calcium-dependent inactivation by the distal carboxy tail, 2021, Journal of Biological Chemistry
  • Resolving the molecular fingerprint of the distal carboxy tail in modulating CaV1 calcium dependent inactivation, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • P160 A deep intronic variant c.862+870C>T correlated with GNE myopathy and thrombocytopenia, 2023, Neuromuscular Disorders
  • 555PMultisystem involvement in oculopharyngodistal myopathy: insights into cardiac manifestations and genotype-phenotype correlations, 2025, Neuromuscular Disorders

Their collaborative work often involved frequent coauthors such as Manu Ben-Johny, Lingjie Sang, Daiana C.O. Vieira, Ivy E. Dick, and Mingshi Gao. These collaborations contributed to advancing knowledge in several interrelated areas of biology and medicine.

David T. Yue published predominantly in the following scientific venues:

  • Neuromuscular Disorders
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Their research fields included:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their subfields of study notably involved:

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Physiology
  • Cell Biology
  • Cellular and Molecular Neuroscience

Key topics addressed across their work included:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Nicotinic Acetylcholine Receptors Study
  • Erythrocyte Function and Pathophysiology
  • Hemoglobin structure and function
  • Neuroscience and Neuropharmacology Research
  • Inflammatory Myopathies and Dermatomyositis

Best Publications

  • Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels.

    Blaise Z Peterson;Carla D DeMaria;David T Yue

  • Preassociation of Calmodulin with Voltage-Gated Ca2+ Channels Revealed by FRET in Single Living Cells

    Michael G. Erickson;Badr A. Alseikhan;Blaise Z. Peterson;David T. Yue

  • Calmodulin bifurcates the local Ca 2+ signal that modulates P/Q-type Ca 2+ channels

    Carla D. DeMaria;Tuck Wah Soong;Badr A. Alseikhan;Rebecca S. Alvania

  • Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes

    David T. Yue;Stefan Herzig;Eduardo Marban

  • Unified mechanisms of Ca2+ regulation across the Ca2+ channel family.

    Haoya Liang;Carla D. DeMaria;Carla D. DeMaria;Michael G. Erickson;Masayuki X. Mori

  • Essential Ca2+-Binding Motif for Ca2+-Sensitive Inactivation of L-Type Ca2+ Channels

    Marita de Leon;Yan Wang;Lisa Jones;Edward Perez-Reyes

  • Molecular localization of an ion-binding site within the pore of mammalian sodium channels.

    Peter H. Backx;David T. Yue;John H. Lawrence;Eduardo Marban

  • Contractility-dependent curvilinearity of end-systolic pressure-volume relations.

    Daniel Burkhoff;Seiryo Sugiura;David T. Yue;Kiichi Sagawa

  • Mechanism of Ca2+-sensitive inactivation of L-type Ca2+ channels

    John P. Imredy;David T. Yue

  • Intracellular calcium transients underlying the short‐term force‐interval relationship in ferret ventricular myocardium.

    W G Wier;D T Yue

  • FRET Two-Hybrid Mapping Reveals Function and Location of L-Type Ca2+ Channel CaM Preassociation

    Michael G. Erickson;Haoya Liang;Masayuki X. Mori;David T. Yue

  • Novel functional properties of Ca2+ channel β subunits revealed by their expression in adult rat heart cells

    Henry M. Colecraft;Badr Alseikhan;Shoji X. Takahashi;Dipayan Chaudhuri

  • Intracellular free calcium concentration measured with 19F NMR spectroscopy in intact ferret hearts

    Eduardo Marban;Masafumi Kitakaze;Hideo Kusuoka;James K. Porterfield

  • A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels.

    Ivy E. Dick;Michael R. Tadross;Haoya Liang;Lai Hock Tay

  • Mechanically induced action potential changes and arrhythmia in isolated and in situ canine hearts.

    Michael R Franz;Daniel Burkhoff;David T Yue;Kiichi Sagawa

  • Quantification of [Ca2+]i in perfused hearts. Critical evaluation of the 5F-BAPTA and nuclear magnetic resonance method as applied to the study of ischemia and reperfusion.

    E. Marban;M. Kitakaze;Y. Koretsune;D. T. Yue

  • Critical Determinants of Ca2+-Dependent Inactivation within an EF-Hand Motif of L-Type Ca2+ Channels

    Blaise Z. Peterson;Joanna S. Lee;Jennifer G. Mulle;Yan Wang

  • Functional stoichiometry and local enrichment of calmodulin interacting with Ca2+ channels

    Masayuki X. Mori;Michael G. Erickson;David T. Yue

  • Mechanism of local and global Ca2+ sensing by calmodulin in complex with a Ca2+ channel.

    Michael R. Tadross;Ivy E. Dick;David T. Yue

  • Preferential Closed-State Inactivation of Neuronal Calcium Channels

    Parag G Patil;David L Brody;David T Yue

Frequent Co-Authors

Eduardo Marbán
Eduardo Marbán Cedars-Sinai Medical Center
Gordon F. Tomaselli
Gordon F. Tomaselli Johns Hopkins University
Parag G. Patil
Parag G. Patil University of Michigan–Ann Arbor
David L. Brody
David L. Brody Uniformed Services University of the Health Sciences
Brian O'Rourke
Brian O'Rourke Johns Hopkins University
Richard W. Tsien
Richard W. Tsien New York University
Daniel J. Leahy
Daniel J. Leahy Johns Hopkins University School of Medicine
Peter H. Backx
Peter H. Backx York University
Rachael L. Neve
Rachael L. Neve Harvard University

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