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Paula M. Vertino

Paula M. Vertino

D-Index & Metrics

Molecular Biology

D-Index
57
Citations
15125
World Ranking
2136
National Ranking
1062

Overview

Paula M. Vertino is affiliated with Emory University in the United States and conducts research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work covers significant areas within molecular biology, oncology, pediatrics, perinatology and child health, hematology, and immunology.

Their main topics of research include:

  • Epigenetics and DNA Methylation
  • Cancer survivorship and care
  • Childhood Cancer Survivors' Quality of Life
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Acute Myeloid Leukemia Research
  • Genomics and Chromatin Dynamics

Vertino has contributed to multiple publications, with a focus on cancer and molecular biology research. Some recent notable papers include:

  • Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer, 2021, Nature Communications
  • Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning, 2020, Science Advances
  • Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma, 2022, Cell Reports
  • A single-arm pilot study of a mobile health exercise intervention (GO-EXCAP) in older patients with myeloid neoplasms, 2022, Blood Advances
  • Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma, 2021, Clinical Cancer Research

Frequent coauthors collaborating with Vertino include:

  • Sagar Lonial
  • Benjamin G. Barwick
  • Michelle C. Janelsins
  • Karen M. Mustian
  • Kah Poh Loh

Vertino's research is often published in leading scientific journals and venues including:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Geriatric Oncology
  • Blood
  • Cell Reports

Best Publications

  • ALTERATIONS IN DNA METHYLATION : A FUNDAMENTAL ASPECT OF NEOPLASIA

    Stephen B. Baylin;James G. Herman;Jeremy R. Graff;Paula M. Vertino

  • CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

    Yanni Lin;Thomas J. Cradick;Matthew T. Brown;Harshavardhan Deshmukh

  • Natural mutagenesis of human genomes by endogenous retrotransposons.

    Rebecca C. Iskow;Michael T. McCabe;Michael T. McCabe;Ryan E. Mills;Spencer Torene

  • Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation.

    Hideharu Hashimoto;Yiwei Liu;Anup K. Upadhyay;Yanqi Chang

  • MAPPING PATTERNS OF CPG ISLAND METHYLATION IN NORMAL AND NEOPLASTIC CELLS IMPLICATES BOTH UPSTREAM AND DOWNSTREAM REGIONS IN DE NOVO METHYLATION

    Jeremy R. Graff;James G. Herman;Sanna Myöhänen;Stephen B. Baylin

  • De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase.

    Paula M. Vertino;Ray Whay Chiu Yen;Jin Gao;Stephen B. Baylin

  • Increased Cytosine DNA-Methyltransferase Activity During Colon Cancer Progression

    Jean Pierre J. Issa;Paula M. Vertino;Jianjun Wu;Sudha Sazawal

  • Predicting aberrant CpG island methylation.

    F. A. Feltus;E. K. Lee;E. K. Lee;J. F. Costello;Christoph Plass

  • TMS1 , a Novel Proapoptotic Caspase Recruitment Domain Protein, Is a Target of Methylation-induced Gene Silencing in Human Breast Cancers

    Kerry E. Conway;Beth B. McConnell;Claire E. Bowring;Carlton D. Donald

  • Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications

    Michael T. McCabe;Johann C. Brandes;Paula M. Vertino

  • Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis

    Jean Pierre J Issa;Paula M. Vertino;Corinne D. Boehm;Irene F. Newsham

  • Isolation and characterization of the cDNA encoding human DNA methyltransferase

    Ray whay Chiu Yen;Paula M. Vertino;Barry D. Nelkin;Jane J. Yu

  • Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase

    Krithika Subramanian;Da Jia;Priya Kapoor-Vazirani;Doris R. Powell

  • Abnormal patterns of DNA methylation in human neoplasia: Potential consequences for tumor progression

    S B Baylin;M Makos;J J Wu;R W Yen

  • Molecular coupling of DNA methylation and histone methylation

    Hideharu Hashimoto;Paula M Vertino;Xiaodong Cheng

  • Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

    Jose T. Thaiparambil;Laura Bender;Thota Ganesh;Erik Kline

  • A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

    Emma C. Scott;Eugene J. Gardner;Ashiq Masood;Nelson T. Chuang

  • Restoration of Tamoxifen Sensitivity in Estrogen Receptor- Negative Breast Cancer Cells: Tamoxifen-Bound Reactivated ER Recruits Distinctive Corepressor Complexes

    Dipali Sharma;Neeraj K. Saxena;Nancy E. Davidson;Paula M. Vertino

  • Leptin-induced Growth Stimulation of Breast Cancer Cells Involves Recruitment of Histone Acetyltransferases and Mediator Complex to CYCLIN D1 Promoter via Activation of Stat3

    Neeraj K. Saxena;Paula M. Vertino;Frank A. Anania;Dipali Sharma

  • Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways.

    D Sharma;N K Saxena;P M Vertino;F A Anania

Frequent Co-Authors

Lawrence H. Boise
Lawrence H. Boise Emory University
Sagar Lonial
Sagar Lonial Emory University
Xiaodong Cheng
Xiaodong Cheng The University of Texas MD Anderson Cancer Center
Stephen B. Baylin
Stephen B. Baylin Johns Hopkins University
John R. Horton
John R. Horton The University of Texas MD Anderson Cancer Center
Karen N. Conneely
Karen N. Conneely Emory University
Carlos S. Moreno
Carlos S. Moreno Emory University
Vikas Gupta
Vikas Gupta Princess Margaret Cancer Centre
Xing Zhang
Xing Zhang The University of Texas MD Anderson Cancer Center
Haian Fu
Haian Fu Emory University

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