Ramesh Akkina mainly focuses on Virology, Virus, Small interfering RNA, Immunology and RNA. His study in Virology is interdisciplinary in nature, drawing from both Humanized mouse, In vivo, T cell and Genetic enhancement. His Genetic enhancement study integrates concerns from other disciplines, such as Progenitor cell and Lentivirus.
The Small interfering RNA study combines topics in areas such as Molecular biology, Viral entry and RNA interference. The study incorporates disciplines such as Gene expression and Aptamer in addition to RNA. His work deals with themes such as Antibody and Stem cell, which intersect with Immune system.
His primary scientific interests are in Virology, Immunology, Virus, Genetic enhancement and Humanized mouse. His studies in Virology integrate themes in fields like Stem cell, Gene, In vivo and Small interfering RNA. His study in Immunology is interdisciplinary in nature, drawing from both Nod and Acquired immunodeficiency syndrome.
His work on Influenza A virus and Orthomyxoviridae as part of general Virus study is frequently connected to Pestivirus and Bacterial virus, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Ramesh Akkina has included themes like Cell culture, Small hairpin RNA, Transduction, Gene silencing and Ribozyme in his Genetic enhancement study. His Humanized mouse study also includes fields such as
His primary areas of study are Virology, Humanized mouse, Virus, Immunology and Viral load. His Virology research is multidisciplinary, incorporating elements of In vivo, Acquired immunodeficiency syndrome, Immune system, Adaptation and Drug. His In vivo research is multidisciplinary, relying on both T cell and In vitro.
His studies deal with areas such as Pharmacology and Virulence as well as Humanized mouse. Within one scientific family, Ramesh Akkina focuses on topics pertaining to Gene under Virus, and may sometimes address concerns connected to Vesicular stomatitis virus. His work on Malaria as part of general Immunology study is frequently linked to Integrase inhibitor, therefore connecting diverse disciplines of science.
Ramesh Akkina mainly investigates Virology, Humanized mouse, Virus, T cell and Viral envelope. His work deals with themes such as Immunohistochemistry, In situ hybridization, RNA, Immunofluorescence and Regulation of gene expression, which intersect with Virology. Ramesh Akkina is doing genetic studies as part of his Immune system and Immunology and Humanized mouse investigations.
His Immunology research includes themes of Nod and Acquired immunodeficiency syndrome. The various areas that he examines in his T cell study include RNA interference, Transcriptional regulation and Gene silencing. His Viral envelope research includes elements of Vesicular stomatitis virus, Pseudotyping and Transduction.
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High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G.
Ramesh K. Akkina;Raquel M. Walton;Meng Liang Chen;Qi Xiang Li.
Journal of Virology (1996)
Long-Term Inhibition of HIV-1 Infection in Primary Hematopoietic Cells by Lentiviral Vector Delivery of a Triple Combination of Anti-HIV shRNA, Anti-CCR5 Ribozyme, and a Nucleolar-Localizing TAR Decoy
Ming Jie Li;James Kim;Shirley Li;John Zaia.
Molecular Therapy (2005)
Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
Jiehua Zhou;Piotr Swiderski;Haitang Li;Jane Zhang.
Nucleic Acids Research (2009)
An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4+ T Cell Decline in Humanized Mice
Charles Preston Neff;Jiehua Zhou;Leila Remling;Jes Kuruvilla.
Science Translational Medicine (2011)
Identification of Novel Influenza A Virus Proteins Translated from PA mRNA
Yukiko Muramoto;Takeshi Noda;Eiryo Kawakami;Ramesh Akkina.
Journal of Virology (2013)
Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages.
Akhil Banerjea;Ming Jie Li;Gerhard Bauer;Leila Remling.
Molecular Therapy (2003)
Bispecific Short Hairpin siRNA Constructs Targeted to CD4, CXCR4, and CCR5 Confer HIV-1 Resistance
Joseph S Anderson;Akhil Banerjea;Ramesh Akkina.
New generation humanized mice for virus research: comparative aspects and future prospects.
HIV-1 infection and CD4 T cell depletion in the humanized Rag2 -/- γc -/- (RAG-hu) mouse model
Bradford K Berges;William H Wheat;Brent E Palmer;Elizabeth Connick.
Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2−/−γc−/− (RAG-hu) mice
Bradford K. Berges;Sarah R. Akkina;Joy M. Folkvord;Elizabeth Connick.
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