World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
7482
World Ranking
18111
National Ranking
1426

Overview

Colin M. Lazarus is affiliated with the University of Bristol in the United Kingdom and has produced a body of research focusing primarily on microbial natural products and biosynthesis, with significant intersections in fungal biology and applications. Their publication record spans multiple subfields including pharmacology, molecular biology, materials chemistry, ecology, evolution, behavior and systematics, and plant science, indicating a multidisciplinary approach to life sciences.

Lazarus's recent research papers include:

  • C-Methylation controls the biosynthetic programming of alternapyrone, 2022, Organic & Biomolecular Chemistry
  • Cleaning the Cellular Factory-Deletion of McrA in Aspergillus oryzae NSAR1 and the Generation of a Novel Kojic Acid Deficient Strain for Cleaner Heterologous Production of Secondary Metabolites, 2021, Frontiers in Fungal Biology
  • Fusarochromene, a novel tryptophan-derived metabolite from Fusarium sacchari, 2020, Organic & Biomolecular Chemistry
  • Investigating Fungal Biosynthetic Pathways Using Heterologous Gene Expression: Aspergillus oryzae as a Heterologous Host, 2022, Methods in molecular biology
  • SAXS reveals highly flexible interdomain linkers of tandem acyl carrier protein-thioesterase domains from a fungal nonreducing polyketide synthase, 2020, FEBS Letters

The scientist frequently collaborates with several coauthors who have contributed to multiple projects, including Kate M. J. de Mattos-Shipley, Pakorn Wattana-Amorn, Christine L. Willis, Supachai Vuttipongchaikij, and Waraporn Bunnak.

Lazarus has published repeatedly in certain scientific venues such as:

  • Organic & Biomolecular Chemistry
  • Methods in molecular biology
  • Frontiers in Fungal Biology
  • FEBS Letters
  • ChemBioChem

Their primary fields of study encompass medicine as well as biochemistry, genetics, and molecular biology. Within these, Lazarus's work touches on the following subfields:

  • Pharmacology
  • Molecular Biology
  • Materials Chemistry
  • Ecology, Evolution, Behavior and Systematics
  • Plant Science

The main topics they focus on in their research are:

  • Microbial Natural Products and Biosynthesis
  • Fungal Biology and Applications
  • Plant biochemistry and biosynthesis
  • Plant Gene Expression Analysis
  • Plant and fungal interactions
  • Mycotoxins in Agriculture and Food
  • Microbial Metabolism and Applications

Best Publications

  • Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants

    Baoxiu Qi;Baoxiu Qi;Tom Fraser;Sam Mugford;Gary Dobson

  • Members of a new family of DNA-binding proteins bind to a conserved cis-element in the promoters of alpha-Amy2 genes

    Paul J. Rushton;Heather Macdonald;Alison K. Huttly;Colin M. Lazarus

  • Fusarin C Biosynthesis in Fusarium moniliforme and Fusarium venenatum

    Zhongshu Song;Russell J. Cox;Colin M. Lazarus;Thomas J. Simpson

  • Auxin transport through non-hair cells sustains root-hair development.

    Angharad R. Jones;Eric M. Kramer;Eric M. Kramer;Kirsten Knox;Kirsten Knox;Ranjan Swarup

  • Isolation of a Δ5-Fatty Acid Desaturase Gene fromMortierella alpina

    LV Michaelson;Colin M Lazarus;G Griffiths;JA Napier

  • Design and utility of oligonucleotide gene probes for fungal polyketide synthases

    Thomas P Nicholson;Brian A.M Rudd;Mike Dawson;Colin M Lazarus

  • Ketosynthase Domain Probes Identify Two Subclasses of Fungal Polyketide Synthase Genes

    Lewis E.H Bingle;Thomas J Simpson;Colin M Lazarus

  • Identification of a cDNA encoding a novel C18-Δ9 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana1

    Baoxiu Qi;Frédéric Beaudoin;Tom Fraser;A.Keith Stobart

  • Arachidonic acid: an evolutionarily conserved signaling molecule modulates plant stress signaling networks

    Tatyana Savchenko;Justin W. Walley;Justin W. Walley;E. Wassim Chehab;Yanmei Xiao

  • Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis

    Jack Davison;Ahmed al Fahad;Menghao Cai;Zhongshu Song

  • Biosynthesis of the 2-Pyridone Tenellin in the Insect Pathogenic Fungus Beauveria bassiana

    Kirstin L. Eley;Laura M. Halo;Zhongshu Song;Henry Powles

  • Functional identification of a fatty acid Δ5 desaturase gene from Caenorhabditis elegans

    Louise V. Michaelson;Johnathan A. Napier;Mervyn Lewis;Gareth Griffiths

  • Secretion of a wheat α-amylase expressed in yeast

    Steven J. Rothstein;Colin M. Lazarus;Wendy E. Smith;David C. Baulcombe

  • Authentic Heterologous Expression of the Tenellin Iterative Polyketide Synthase Nonribosomal Peptide Synthetase Requires Coexpression with an Enoyl Reductase

    Laura M. Halo;James W. Marshall;Ahmed A. Yakasai;Zhongshu Song

  • Late stage oxidations during the biosynthesis of the 2-pyridone tenellin in the entomopathogenic fungus Beauveria bassiana.

    Laura M Halo;Mary N Heneghan;Ahmed A Yakasai;Zhongshu Song

  • First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multigene Cluster

    Mary N. Heneghan;Ahmed A. Yakasai;Laura M. Halo;Zhongshu Song

  • Rational domain swaps decipher programming in fungal highly reducing polyketide synthases and resurrect an extinct metabolite.

    Katja M. Fisch;Walid Bakeer;Walid Bakeer;Ahmed A. Yakasai;Zhongshu Song

  • Overexpression of auxin-binding protein enhances the sensitivity of guard cells to auxin

    James M. Bauly;Ian M. Sealy;Heather Macdonald;Jane Brearley

  • α-amylase genes of wheat are two multigene families which are differentially expressed.

    Colin M. Lazarus;David C. Baulcombe;Robert A. Martienssen

  • Retention of maize auxin-binding protein in the endoplasmic reticulum : quantifying escape and the role of auxin

    J Henderson;JM Bauly;DA Ashford;SC Oliver

Frequent Co-Authors

Johnathan A. Napier
Johnathan A. Napier Rothamsted Research
Russell J. Cox
Russell J. Cox University of Hannover
Thomas J. Simpson
Thomas J. Simpson University of Bristol
Olga Sayanova
Olga Sayanova Rothamsted Research
Chris Hawes
Chris Hawes Oxford Brookes University
Ulrich Zähringer
Ulrich Zähringer Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Ernst Heinz
Ernst Heinz Universität Hamburg
David C. Baulcombe
David C. Baulcombe University of Cambridge
Robert A. Martienssen
Robert A. Martienssen Cold Spring Harbor Laboratory
Joanne Cable
Joanne Cable Cardiff University

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