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Genetics
UK
2024
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Genetics

D-Index
130
Citations
72544
World Ranking
255
National Ranking
45

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award
  • 2015 - Fellow of the Royal Society of Edinburgh
  • 2014 - Gruber Prize in Genetics
  • 2012 - International Balzan Prize
  • 2010 - Wolf Prize in Agriculture for his pioneering discovery of gene regulation by small inhibitory RNA molecules in plants, which is of profound importance not only for agriculture, but also for biology as a whole, including the field of medicine.
  • 2008 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 2008 - Benjamin Franklin Medal, Franklin Institute
  • 2005 - Member of the National Academy of Sciences
  • 2002 - Member of Academia Europaea
  • 2001 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

David C. Baulcombe is affiliated with the University of Cambridge in the United Kingdom. Their research spans primarily Agricultural and Biological Sciences, with a significant focus on Biochemistry, Genetics, and Molecular Biology. The subfields they contribute to include Plant Science, Molecular Biology, Horticulture, Food Science, and Insect Science.

The research topics they have worked on cover areas such as Plant Virus Research Studies, Chromosomal and Genetic Variations, Plant Molecular Biology Research, Plant Parasitism and Resistance, CRISPR and Genetic Engineering, Plant tissue culture and regeneration, and Plant nutrient uptake and metabolism.

Frequent coauthors collaborating with David C. Baulcombe include Sebastian Müller, Sara López-Gomollón, Zhengming Wang, Cláudia Martinho, and Yingtian Deng.

They have published extensively in venues including bioRxiv (Cold Spring Harbor Laboratory), Nature Reviews Molecular Cell Biology, Nature Communications, Annual Review of Virology, and Molecular Biology and Evolution.

Representative recent papers include:

  • "Roles of RNA silencing in viral and non-viral plant immunity and in the crosstalk between disease resistance systems," 2022, Nature Reviews Molecular Cell Biology
  • "Transposon age and non-CG methylation," 2020, Nature Communications
  • "The Role of Viruses in Identifying and Analyzing RNA Silencing," 2022, Annual Review of Virology
  • "Viral Fitness Determines the Magnitude of Transcriptomic and Epigenomic Reprograming of Defense Responses in Plants," 2020, Molecular Biology and Evolution
  • "Interspecific hybridization in tomato influences endogenous viral sRNAs and alters gene expression," 2022, Genome Biology

David C. Baulcombe's career has been recognized with several awards and honors. These include Fellow of the Royal Society of Edinburgh (2015), the Gruber Prize in Genetics (2014), the International Balzan Prize (2012), and the Wolf Prize in Agriculture (2010) noted for the discovery of gene regulation by small inhibitory RNA molecules in plants. Other recognitions include the Albert Lasker Award for Basic Medical Research (2008), the Benjamin Franklin Medal from the Franklin Institute (2008), membership in the National Academy of Sciences (2005), Academia Europaea (2002), Fellowship of the Royal Society (United Kingdom, 2001), membership of the European Molecular Biology Organization (EMBO), and fellowship in The Academy of Medical Sciences (United Kingdom).

Best Publications

  • A species of small antisense RNA in posttranscriptional gene silencing in plants.

    Andrew J. Hamilton;David C. Baulcombe

  • RNA silencing in plants

    David Baulcombe

  • Retraction: ‘Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana’

    Gianinna Brigneti;Olivier Voinnet;Wan‐Xiang Li;Liang‐Hui Ji

  • An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus.

    Olivier Voinnet;Susana Rivas;Pere Mestre;David Baulcombe

  • An RNA-Dependent RNA Polymerase Gene in Arabidopsis Is Required for Posttranscriptional Gene Silencing Mediated by a Transgene but Not by a Virus

    Tamas Dalmay;Andrew Hamilton;Stephen Rudd;Susan Angell

  • Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants.

    Olivier Voinnet;Yvonne M. Pinto;David C. Baulcombe

  • Two classes of short interfering RNA in RNA silencing

    Andrew Hamilton;Olivier Voinnet;Louise Chappell;David Baulcombe

  • Criteria for Annotation of Plant MicroRNAs

    Blake C. Meyers;Michael J. Axtell;Bonnie Bartel;David P. Bartel

  • Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs.

    N. Baumberger;D. C. Baulcombe

  • Initiation and Maintenance of Virus-Induced Gene Silencing

    M. Teresa Ruiz;Olivier Voinnet;David C. Baulcombe

  • Technical Advance: Tobacco rattle virus as a vector for analysis of gene function by silencing

    Frank Ratcliff;Ana Montserrat Martin-Hernandez;David C. Baulcombe

  • A similarity between viral defense and gene silencing in plants.

    Frank Ratcliff;Bryan D. Harrison;Bryan D. Harrison;David C. Baulcombe;David C. Baulcombe

  • Modulation of floral development by a gibberellin-regulated microRNA

    Patrick Achard;Alan Herr;David C. Baulcombe;Nicholas P. Harberd

  • Fast forward genetics based on virus-induced gene silencing

    David C Baulcombe

  • The Rx Gene from Potato Controls Separate Virus Resistance and Cell Death Responses

    Abdelhafid Bendahmane;Konstantin Kanyuka;David C. Baulcombe

  • Systemic Spread of Sequence-Specific Transgene RNA Degradation in Plants Is Initiated by Localized Introduction of Ectopic Promoterless DNA

    Olivier Voinnet;Philippe Vain;Susan Angell;David C Baulcombe

  • RNA polymerase IV directs silencing of endogenous DNA

    Alan J. Herr;Morten B. Jensen;Morten B. Jensen;Tamas Dalmay;Tamas Dalmay;David C. Baulcombe;David C. Baulcombe

  • A Viral Movement Protein Prevents Spread of the Gene Silencing Signal in Nicotiana benthamiana

    Olivier Voinnet;Carsten Lederer;David C Baulcombe

  • Small Silencing RNAs in Plants Are Mobile and Direct Epigenetic Modification in Recipient Cells

    Attila Molnar;Charles W. Melnyk;Andrew Bassett;Thomas J. Hardcastle

  • Reaping the Benefits: Science and the sustainable intensification of global agriculture

    Bill Davies;David Baulcombe;Ian Crute;Jim Dunwell

Frequent Co-Authors

Bryan D. Harrison
Bryan D. Harrison James Hutton Institute
Abdelhafid Bendahmane
Abdelhafid Bendahmane University of Paris-Saclay
M. A. Mayo
M. A. Mayo James Hutton Institute
Robert A. Martienssen
Robert A. Martienssen Cold Spring Harbor Laboratory
Michael W. Bevan
Michael W. Bevan John Innes Centre
Jonathan D. G. Jones
Jonathan D. G. Jones University of East Anglia
Tamas Dalmay
Tamas Dalmay University of East Anglia
David J. Studholme
David J. Studholme University of Exeter
Colin M. Lazarus
Colin M. Lazarus University of Bristol

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