Guy A. Perkins

Overview

Best Publications

• Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.

  Tomomi Kuwana;Mason R. Mackey;Guy Perkins;Mark H. Ellisman

  1880
  Citations

• NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

  Zhenyu Zhong;Atsushi Umemura;Atsushi Umemura;Elsa Sanchez-Lopez;Shuang Liang

  1187
  Citations

• Mitochondrial fragmentation in neurodegeneration

  Andrew B. Knott;Guy Perkins;Robert Schwarzenbacher;Ella Bossy-Wetzel

  1102
  Citations

• Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

  Mark J Barsoum;Hua Yuan;Akos A Gerencser;Géraldine Liot

  770
  Citations

• Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain

  Jean-Ehrland Ricci;Cristina Muñoz-Pinedo;Patrick Fitzgerald;Béatrice Bailly-Maitre

  693
  Citations

• Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

  Jun Hee Lee;Andrei V. Budanov;Eek Joong Park;Ryan Birse

  616
  Citations

• Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

  Wenjun Song;Jin-jin Chen;Alejandra M. Petrilli;Géraldine Liot

  573
  Citations

• Correction: Corrigendum: Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration

  Myoung Sup Shim;Yuji Takihara;Keun-Young Kim;Takeshi Iwata

  509
  Citations

• Electron Tomography of Neuronal Mitochondria: Three-Dimensional Structure and Organization of Cristae and Membrane Contacts

  G. Perkins;C. Renken;M.E. Martone;S.J. Young

  480
  Citations

• Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels.

  Ella Bossy-Wetzel;Maria V Talantova;Wilson D Lee;Marion N Schölzke

  453
  Citations

• The Pro-Apoptotic Proteins, Bid and Bax, Cause a Limited Permeabilization of the Mitochondrial Outer Membrane That Is Enhanced by Cytosol

  Ruth M Kluck;Mauro Dogli Esposti;Guy Perkins;Christian Renken

  407
  Citations

• ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function

  Manjula Darshi;Vincent L. Mendiola;Mason R. Mackey;Anne N. Murphy

  350
  Citations

• Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle.

  Benjamin G Kopek;Guy Perkins;David J Miller;Mark H Ellisman

  339
  Citations

• Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release.

  Oliver von Ahsen;Christian Renken;Guy Perkins;Ruth M. Kluck

  331
  Citations

• Covalently Linked Au Nanoparticles to a Viral Vector: Potential for Combined Photothermal and Gene Cancer Therapy

  Maaike Everts;Vaibhav Saini;Jennifer L. Leddon;Robbert J. Kok

  319
  Citations

• Opa1-Mediated Cristae Opening Is Bax/Bak and BH3 Dependent, Required for Apoptosis, and Independent of Bak Oligomerization

  Ryuji Yamaguchi;Lydia Lartigue;Guy A Perkins;Ray T Scott

  313
  Citations

• Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

  Mei G. Sun;James Williams;Cristina Munoz-Pinedo;Guy A. Perkins

  311
  Citations

• Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3

  Jun Hee Lee;Jun Hee Lee;Andrei V. Budanov;Andrei V. Budanov;Saswata Talukdar;Eek Joong Park

  303
  Citations

• Insight into mitochondrial structure and function from electron tomography

  T.G Frey;C.W Renken;C.W Renken;G.A Perkins

  258
  Citations

• ChChd3, an Inner Mitochondrial Membrane Protein is Essential for Maintaining Cristae Integrity and Mitochondrial Function

  Manjula Darshi;Guy A Perkins;Mason R Mackey;Susanna Petrosyan

  2
  Citations