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Biology and Biochemistry

D-Index
47
Citations
5972
World Ranking
18796
National Ranking
7675

Overview

Ellen L. Neidle is affiliated with the University of Georgia in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions across related subfields such as molecular biology, genetics, molecular medicine, pharmacology, and pollution.

The main topics of Ellen L. Neidle's work include bacterial genetics and biotechnology, microbial metabolic engineering and bioproduction, CRISPR and genetic engineering, antibiotic resistance in bacteria, evolution and genetic dynamics, microbial natural products and biosynthesis, and genomics and phylogenetic studies.

Frequent co-authors collaborating with Ellen L. Neidle are:

  • Chantel V. Duscent-Maitland
  • Stacy R. Bedore
  • Alyssa C. Baugh
  • Melissa P. Tumen-Velasquez
  • Isabel Pardo

They have published regularly in certain venues, including:

  • Applied and Environmental Microbiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Metabolic Engineering
  • Nucleic Acids Research
  • Annual Review of Microbiology

Some recent publications by Ellen L. Neidle include:

  • Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1, 2020, Metabolic Engineering
  • Development of a genetic toolset for the highly engineerable and metabolically versatile Acinetobacter baylyi ADP1, 2020, Nucleic Acids Research
  • Versatility and Complexity: Common and Uncommon Facets of LysR-Type Transcriptional Regulators, 2023, Annual Review of Microbiology
  • Regulation of l - and d -Aspartate Transport and Metabolism in Acinetobacter baylyi ADP1, 2022, Applied and Environmental Microbiology
  • CsrA-mediated regulation of a virulence switch in Acinetobacter baumannii, 2025, mBio

Their body of research reflects an integrated approach to understanding bacterial functions and genetics, microbial metabolic capabilities, and mechanisms of resistance and regulation within bacteria. The frequent themes across their work include genetic engineering tools, metabolic pathway analysis, and bacterial transport and regulatory systems.

Best Publications

  • Functional and Evolutionary Relationships Among Diverse Oxygenases

    S Harayama;M Kok;E L Neidle

  • Nucleotide sequences of the Acinetobacter calcoaceticus benABC genes for benzoate 1,2-dioxygenase reveal evolutionary relationships among multicomponent oxygenases.

    E L Neidle;C Hartnett;L N Ornston;A Bairoch

  • A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.

    Sam J. B. Mallinson;Melodie M. Machovina;Melodie M. Machovina;Rodrigo L. Silveira;Rodrigo L. Silveira;Marc Garcia-Borràs

  • Potential DNA slippage structures acquired during evolutionary divergence of Acinetobacter calcoaceticus chromosomal benABC and Pseudomonas putida TOL pWW0 plasmid xylXYZ, genes encoding benzoate dioxygenases.

    S Harayama;M Rekik;A Bairoch;E L Neidle

  • Key Aromatic-Ring-Cleaving Enzyme, Protocatechuate 3,4-Dioxygenase, in the Ecologically Important Marine Roseobacter Lineage

    Alison Buchan;Lauren S. Collier;Ellen L. Neidle;Mary Ann Moran

  • Regulation of Benzoate Degradation in Acinetobacter sp. Strain ADP1 by BenM, a LysR-Type Transcriptional Activator

    Lauren S. Collier;George L. Gaines;Ellen L. Neidle

  • DNA sequence of the Acinetobacter calcoaceticus catechol 1,2-dioxygenase I structural gene catA: evidence for evolutionary divergence of intradiol dioxygenases by acquisition of DNA sequence repetitions.

    E L Neidle;C Hartnett;S Bonitz;L N Ornston

  • Expression of the Rhodobacter sphaeroides hemA and hemT genes, encoding two 5-aminolevulinic acid synthase isozymes.

    E L Neidle;S Kaplan

  • DNA sequences of genes encoding Acinetobacter calcoaceticus protocatechuate 3,4-dioxygenase: evidence indicating shuffling of genes and of DNA sequences within genes during their evolutionary divergence.

    C. Hartnett;E. L. Neidle;Ka-Leung Ngai;L. N. Ornston

  • Selection for Gene Clustering by Tandem Duplication

    Andrew B Reams;Ellen L Neidle

  • cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.

    Ellen L Neidle;Christopher Hartnett;L Nicholas Ornston;Amos Marc Bairoch

  • Characterization of Acinetobacter calcoaceticus catM, a repressor gene homologous in sequence to transcriptional activator genes.

    E L Neidle;C Hartnett;L N Ornston

  • benK encodes a hydrophobic permease-like protein involved in benzoate degradation by Acinetobacter sp. strain ADP1.

    Lauren S. Collier;Nancy N. Nichols;Ellen L. Neidle

  • Distinct effector-binding sites enable synergistic transcriptional activation by BenM, a LysR-type regulator.

    Obidimma C. Ezezika;Sandra Haddad;Todd J. Clark;Ellen L. Neidle

  • Synergistic transcriptional activation by one regulatory protein in response to two metabolites.

    Becky M. Bundy;Lauren S. Collier;Timothy R. Hoover;Ellen L. Neidle

  • Cloning and expression in Escherichia coli of Acinetobacter calcoaceticus genes for benzoate degradation.

    E L Neidle;M K Shapiro;L N Ornston

  • Diversity of the Ring-Cleaving Dioxygenase Gene pcaH in a Salt Marsh Bacterial Community

    Alison Buchan;Ellen L. Neidle;Mary Ann Moran

  • Genome plasticity in Acinetobacter: new degradative capabilities acquired by the spontaneous amplification of large chromosomal segments.

    Andrew B. Reams;Ellen L. Neidle

  • Cloning and expression of Acinetobacter calcoaceticus catechol 1,2-dioxygenase structural gene catA in Escherichia coli.

    E L Neidle;L N Ornston

  • catM encodes a LysR-type transcriptional activator regulating catechol degradation in Acinetobacter calcoaceticus.

    C E Romero-Arroyo;M A Schell;G L Gaines;E L Neidle

Frequent Co-Authors

L N Ornston
L N Ornston Yale University
Gregg T. Beckham
Gregg T. Beckham National Renewable Energy Laboratory
Mark A. Eiteman
Mark A. Eiteman University of Georgia
Shigeaki Harayama
Shigeaki Harayama Chuo University
Donald M. Kurtz
Donald M. Kurtz The University of Texas at San Antonio
Mary Ann Moran
Mary Ann Moran University of Georgia
Amos Marc Bairoch
Amos Marc Bairoch Swiss Institute of Bioinformatics
Samuel Kaplan
Samuel Kaplan The University of Texas Health Science Center at Houston
Michael F. Crowley
Michael F. Crowley National Renewable Energy Laboratory
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles

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