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Wai-Ping Fung-Leung

Wai-Ping Fung-Leung

D-Index & Metrics

Immunology

D-Index
49
Citations
13075
World Ranking
4305
National Ranking
67

Overview

Wai-Ping Fung-Leung is affiliated with Janssen (Belgium) and has contributed to multiple research areas within immunology and medicine. Their work encompasses studies on immune cell function, T-cell and B-cell immunology, and the pathogenesis and treatment of psoriasis.

The scientist has published research in several journals, including:

  • Journal of Allergy and Clinical Immunology
  • European Journal of Pharmacology
  • Pharmacology Research & Perspectives
  • UNC Libraries

Key research topics explored by Wai-Ping Fung-Leung include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Psoriasis: Treatment and Pathogenesis
  • Single-cell and spatial transcriptomics
  • Pain Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Pharmacological Effects of Natural Compounds

Their expertise covers multiple fields of study, notably:

  • Immunology and Microbiology
  • Medicine

Subfields of particular focus include:

  • Immunology
  • Molecular Biology
  • Physiology
  • Neurology
  • Pharmacology

Wai-Ping Fung-Leung has collaborated with several frequent co-authors, including:

  • Karen Ngo
  • James P. Edwards
  • Tadimeti S. Rao
  • Jared Liu
  • Hsin-Wen Chang

Notable recent publications by Wai-Ping Fung-Leung include:

  • Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer, 2020, Journal of Allergy and Clinical Immunology
  • Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse, 2020, European Journal of Pharmacology
  • Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor, 2020, Pharmacology Research & Perspectives
  • Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model, 2024, UNC Libraries

Best Publications

  • Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells

    Shanrong Zhao;Wai-Ping Fung-Leung;Anton Bittner;Karen Ngo

  • Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4.

    A. Rahemtulla;W. P. Fung-Leung;M. W. Schilham;T. M. Kündig

  • Histamine H4 Receptor Mediates Chemotaxis and Calcium Mobilization of Mast Cells

    Claudia L. Hofstra;Pragnya J. Desai;Robin L. Thurmond;Wai-Ping Fung-Leung

  • CD8 is needed for development of cytotoxic T cells but not helper T cells.

    Wai-Ping Fung-Leung;Marco W. Schilham;Amin Rahemtulla;Thomas M. Kündig

  • A Potent and Selective Histamine H4 Receptor Antagonist with Anti-Inflammatory Properties

    Robin L. Thurmond;Pragnya J. Desai;Paul J. Dunford;Wai-Ping Fung-Leung

  • Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.

    Daniel K. Hsu;Ri Yao Yang;Zhixing Pan;Lan Yu

  • Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice.

    Dow-Rhoon Koh;Wai-Ping Fung-Leung;Alexandra Ho;Dawn Gray

  • Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues

    Miranda Van Eck;I. Sophie T. Bos;Wolfgang E. Kaminski;Evelyn Orsó

  • Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation

    Ping Ling;Karen Ngo;Steven Nguyen;Robin L Thurmond

  • Antigen presentation and T cell development in H2-M-deficient mice.

    Wai-Ping Fung-Leung;Charles D. Surh;Monika Liljedahl;Jesse Pang

  • IRAK1: a critical signaling mediator of innate immunity.

    Sridevi Gottipati;Navin L. Rao;Wai-Ping Fung-Leung

  • Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production.

    Palanisamy Kanakaraj;Peter H. Schafer;Druie E. Cavender;Ying Wu

  • Behavioral Characterization of Mice Lacking Histamine H3 Receptors

    Hiroshi Toyota;Christine Dugovic;Muriel Koehl;Aaron D. Laposky

  • Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.

    Wai-Ping Fung-Leung;T. M. Kündig;R. M. Zinkernagel;T. W. Mak

  • Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation

    Pejman Soroosh;Jiejun Wu;Xiaohua Xue;Jiao Song

  • Biological consequences of thrombin receptor deficiency in mice.

    Andrew L Darrow;Wai-Ping Fung-Leung;Richard D Ye;Rosemary J Santulli

  • Defective Interleukin (IL)-18–mediated Natural Killer and T Helper Cell Type 1 Responses in IL-1 Receptor–associated Kinase (IRAK)-deficient Mice

    Palanisamy Kanakaraj;Karen Ngo;Ying Wu;Ana Angulo

  • HLA-DO IS A LYSOSOMAL RESIDENT WHICH REQUIRES ASSOCIATION WITH HLA-DM FOR EFFICIENT INTRACELLULAR TRANSPORT

    M. Liljedahl;T. Kuwana;W. P. Fung-Leung;M. R. Jackson

  • Impaired Immunoproteasome Assembly and Immune Responses in PA28−/− Mice

    Tobias Preckel;Wai Ping Fung-Leung;Zeling Cai;Antonella Vitiello

  • Altered Antigen Presentation in Mice Lacking H2-O

    Monika Liljedahl;Ola Winqvist;Charles D Surh;Phillip Wong

  • Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1.

    Bruce P. Damiano;Wai Man Cheung;Rosemary J. Santulli;Wai Ping Fung-Leung

Frequent Co-Authors

Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Per A. Peterson
Per A. Peterson Scripps Research Institute
Tadimeti S. Rao
Tadimeti S. Rao Vividion Therapeutics
Fu-Tong Liu
Fu-Tong Liu Academia Sinica
Marco W. Schilham
Marco W. Schilham Leiden University Medical Center
Xuejun Liu
Xuejun Liu China Agricultural University
Thomas M. Kündig
Thomas M. Kündig University of Zurich
Richard G. Miller
Richard G. Miller University of Toronto
Charles D. Surh
Charles D. Surh Pohang University of Science and Technology
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre

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