World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
58
Citations
12106
World Ranking
2088
National Ranking
74

Overview

Régine Losson was affiliated with the Institute of Genetics and Molecular and Cellular Biology in France. Their research career focused primarily on the intersection of biochemistry, genetics, and molecular biology with applications in medicine.

The scientist contributed to the fields of molecular biology and hematology. Their main topics of study included:

  • Epigenetics and DNA Methylation
  • Acute Myeloid Leukemia Research
  • RNA modifications and cancer

Losson published at least one recent scientific paper:

  • "Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia," published in 2020 in Nature Communications

Their body of work frequently appeared in the journal Nature Communications.

Collaborations were documented with multiple coauthors, including:

  • Katharina Leonards
  • Marwa Almosailleakh
  • Samantha Tauchmann
  • Frederik Otzen Bagger
  • Cécile Thirant

Throughout their career, Losson explored mechanisms underlying hematological malignancies and the molecular pathways involved in cellular differentiation. Their research included examining the role of specific proteins in gene regulation related to erythroid cells.

Best Publications

  • The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

    B. Le Douarin;C. Zechel;J.M. Garnier;Y. Lutz

  • A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

    B Le Douarin;A L Nielsen;J M Garnier;H Ichinose

  • Interference of nonsense mutations with eukaryotic messenger RNA stability

    Regine Losson;Francois Lacroute

  • Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.

    B Durand;M Saunders;C Gaudon;B Roy

  • Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

    Anders L. Nielsen;José A. Ortiz;Jun You;Mustapha Oulad‐Abdelghani

  • Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

    E. Vom Baur;C. Zechel;D. Heery;M. J. S. Heine

  • Heterochromatin Formation in Mammalian Cells: Interaction between Histones and HP1 Proteins

    Anders Lade Nielsen;Mustapha Oulad-Abdelghani;José A Ortiz;Eumorphia Remboutsika

  • The bromodomain revisited

    François Jeanmougin;Jean-Marie Wurtz;Bertrand Le Douarin;Pierre Chambon

  • NSD1 is essential for early post-implantation development and has a catalytically active SET domain

    Geetha Vani Rayasam;Olivia Wendling;Pierre-Olivier Angrand;Manuel Mark

  • Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators

    Ningwu Huang;Elmar vom Baur;Jean‐Marie Garnier;Thierry Lerouge

  • Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development.

    F. Cammas;M. Mark;P. Dolle;A. Dierich

  • Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2

    Hiroshi Ichinose;Jean-Marie Garnier;Pierre Chambon;Régine Losson

  • Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

    Benjamin Herquel;Khalid Ouararhni;Konstantin Khetchoumian;Mihaela Ignat

  • TIF1γ, a novel member of the transcriptional intermediary factor 1 family

    Letizia Venturini;Letizia Venturini;Jun You;Jun You;Michael Stadler;Michael Stadler;René Galien

  • Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

    María Berdasco;Santiago Ropero;Fernando Setien;Mario F. Fraga

  • Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.

    Konstantin Khetchoumian;Marius Teletin;Johan Tisserand;Manuel Mark

  • NSD3, a New SET Domain-Containing Gene, Maps to 8p12 and Is Amplified in Human Breast Cancer Cell Lines ☆

    Pierre-Olivier Angrand;Françoise Apiou;A.Francis Stewart;Bernard Dutrillaux

  • Common Properties of Nuclear Body Protein SP100 and TIF1α Chromatin Factor: Role of SUMO Modification

    Jacob-S Seeler;Agnes Marchio;Regine Losson;Joana M P Desterro

  • T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor α

    Dongsheng Chen;Marie J. Lucey;Fladia Phoenix;Jorge Lopez-Garcia

  • L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure

    Patrick Trojer;Alina R. Cao;Zhonghua Gao;Yan Li

Frequent Co-Authors

Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Manuel Mark
Manuel Mark Institute of Genetics and Molecular and Cellular Biology
Hinrich Gronemeyer
Hinrich Gronemeyer Institute of Genetics and Molecular and Cellular Biology
Alain Puisieux
Alain Puisieux Claude Bernard University Lyon 1
Pierre Dubus
Pierre Dubus University of Bordeaux
Hiroshi Ichinose
Hiroshi Ichinose Tokyo Institute of Technology
Pascal Dollé
Pascal Dollé Institute of Genetics and Molecular and Cellular Biology
Irwin Davidson
Irwin Davidson Institute of Genetics and Molecular and Cellular Biology
Nabeel Bardeesy
Nabeel Bardeesy Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology in the USA opens doors to a variety of online degrees and career options. Prospective students can benefit from flexible platforms provided by nonprofit online colleges, which prioritize both quality learning and affordability.

For military members or veterans seeking further education, the best online colleges for military offer tailored programs and support, making it easier to balance service and studies.

Students interested in combining biological sciences with community outreach may consider health-adjacent options like an online masters of social work. This degree can open up roles in healthcare, counseling, or research organizations.

Those with a keen interest in the intersection of mind and biology may also explore a master psychologie à distance for accelerated advancement into research or clinical roles.

By considering these related online degrees and pathways, students can align their education with their career goals and personal circumstances.

Best Scientists Citing Régine Losson