Minoru Hasegawa

Overview

Best Publications

• Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis.

  Hasegawa M;Fujimoto M;Kikuchi K;Takehara K

  443
  Citations

• Quantitative Genetic Variation in CD19 Expression Correlates with Autoimmunity

  Shinichi Sato;Minoru Hasegawa;Manabu Fujimoto;Thomas F. Tedder

  441
  Citations

• Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome.

  Yasuhito Hamaguchi;Manabu Fujimoto;Takashi Matsushita;Kenzo Kaji

  424
  Citations

• Clinical correlations with dermatomyositis-specific autoantibodies in adult Japanese patients with dermatomyositis: a multicenter cross-sectional study.

  Yasuhito Hamaguchi;Masataka Kuwana;Kana Hoshino;Minoru Hasegawa

  405
  Citations

• Altered blood B lymphocyte homeostasis in systemic sclerosis: Expanded naive B cells and diminished but activated memory B cells

  Shinichi Sato;Manabu Fujimoto;Minoru Hasegawa;Kazukiko Takehara

  401
  Citations

• Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis.

  Shinichi Sato;Minoru Hasegawa;Kazuhiko Takehara

  388
  Citations

• Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy

  K. Kaji;M. Fujimoto;M. Hasegawa;M. Kondo

  372
  Citations

• Mouse CD20 expression and function.

  Junji Uchida;Youngkyun Lee;Minoru Hasegawa;Yinghua Liang

  352
  Citations

• Serum levels of connective tissue growth factor are elevated in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis.

  Shinichi Sato;Tetsuya Nagaoka;Minoru Hasegawa;Takuya Tamatani

  329
  Citations

• Elevated serum BAFF levels in patients with systemic sclerosis: Enhanced BAFF signaling in systemic sclerosis B lymphocytes

  Takashi Matsushita;Minoru Hasegawa;Koichi Yanaba;Masanari Kodera

  325
  Citations

• CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.

  Eriko Saito;Manabu Fujimoto;Minoru Hasegawa;Kazuhiro Komura

  321
  Citations

• Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins.

  Manabu Fujimoto;Yasuhito Hamaguchi;Kenzo Kaji;Takashi Matsushita

  318
  Citations

• Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancy

  Yuki Ichimura;Takashi Matsushita;Yasuhito Hamaguchi;Kenzo Kaji

  307
  Citations

• Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis.

  M Hasegawa;S Sato;K Takehara

  285
  Citations

• CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.

  Ayumi Yoshizaki;Yohei Iwata;Kazuhiro Komura;Fumihide Ogawa

  279
  Citations

• Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts

  Taiji Nakashima;Masatoshi Jinnin;Keitaro Yamane;Noritoshi Honda

  266
  Citations

• Small solitary pulmonary nodules (< or =1 cm) detected at population-based CT screening for lung cancer: Reliable high-resolution CT features of benign lesions.

  Shodayu Takashima;Shusuke Sone;Feng Li;Yuichiro Maruyama

  257
  Citations

• Delayed Wound Healing in the Absence of Intercellular Adhesion Molecule-1 or L-Selectin Expression

  Tetsuya Nagaoka;Yuko Kaburagi;Yasuhito Hamaguchi;Minoru Hasegawa

  244
  Citations

• B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.

  Minoru Hasegawa;Yasuhito Hamaguchi;Koichi Yanaba;Jean-David Bouaziz

  243
  Citations

• Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial

  Satoshi Ebata;Ayumi Yoshizaki;Koji Oba;Kosuke Kashiwabara

  236
  Citations

• CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms.

  Jonathan C Poe;Yoko Fujimoto;Minoru Hasegawa;Minoru Hasegawa;Karen M Haas

  230
  Citations