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Yuichi Obata

Yuichi Obata

Overview

Yuichi Obata is affiliated with RIKEN in Japan and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Aging, Genetics, Endocrine and Autonomic Systems, as well as Cellular and Molecular Neuroscience.

Their scientific work covers a range of topics with a focus on CRISPR and Genetic Engineering, Genetics, Aging and Longevity in Model Organisms, and mechanisms related to RNA and protein synthesis. They have also engaged in research on Single-cell and Spatial Transcriptomics, Pluripotent Stem Cells, Circadian Rhythm and Melatonin, and Neurobiology with an emphasis on Insect Physiology.

Typical publication venues for Yuichi Obata include:

  • Genome biology
  • Mammalian Genome
  • Methods
  • PLoS Genetics
  • Scientific Reports

Frequent collaborators in their research projects are:

  • K. C. Kent Lloyd
  • Martin Hrabě de Angelis
  • Colin McKerlie
  • Radislav Sedláček
  • Toshihiko Shiroishi

Recent published papers by Yuichi Obata include:

  • "The Deep Genome Project," 2020, Genome biology
  • "Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes," 2020, Methods
  • "High-throughput discovery of genetic determinants of circadian misalignment," 2020, PLoS Genetics
  • "MoG+: a database of genomic variations across three mouse subspecies for biomedical research," 2021, Mammalian Genome
  • "Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation"," 2021, Genome biology

Best Publications

  • Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits

    Keigo Kohara;Michele Pignatelli;Alexander J. Rivest;Hae Yoon Jung

  • NF-κB RelA-deficient Lymphocytes: Normal Development of T Cells and B Cells, Impaired Production of IgA and IgG1 and Reduced Proliferative Responses

    Takahiro S. Doi;Toshitada Takahashi;Osamu Taguchi;Takachika Azuma

  • Genetic differences among C57BL/6 substrains.

    Kazuyuki Mekada;Kuniya Abe;Ayumi Murakami;Satoe Nakamura

  • Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

    Takahiro S. Doi;Michael W. Marino;Toshitada Takahashi;Toshimichi Yoshida

  • Induction of Cardiomyocyte-Like Cells in Infarct Hearts by Gene Transfer of Gata4, Mef2c, and Tbx5

    Kohei Inagawa;Kazutaka Miyamoto;Hiroyuki Yamakawa;Naoto Muraoka

  • Preferential Expression of c-kit Protooncogene Transcripts in Small Cell Lung Cancer

    Yoshitaka Sekido;Yuichi Obata;Ryuzo Ueda;Toyoaki Hida

  • Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories

    Dheeraj S. Roy;Takashi Kitamura;Teruhiro Okuyama;Sachie K. Ogawa

  • Isolation of embryonic stem‐like cells from equine blastocysts and their differentiation in vitro1

    Shigeo Saito;Hideyo Ugai;Ken Sawai;Yusuke Yamamoto

  • Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

    Terrence F Meehan;Nathalie Conte;David B West;Julius O Jacobsen

  • Immunomic analysis of human sarcoma

    Sang-Yull Lee;Yuichi Obata;Masahiro Yoshida;Elisabeth Stockert

  • Expression of cancer/testis (CT) antigens in lung cancer.

    Kouhei Tajima;Yuichi Obata;Hiromi Tamaki;Masahiro Yoshida

  • Generation of cloned calves and transgenic chimeric embryos from bovine embryonic stem-like cells.

    Shigeo Saito;Ken Sawai;Hideyo Ugai;Satoru Moriyasu

  • Relation of GIX antigen of thymocytes to envelope glycoprotein of murine leukemia virus.

    Y Obata;H Ikeda;E Stockert;E A Boyse

  • Efficient Generation of Antigen-Specific Cytotoxic T Cells Using Retrovirally Transduced CD40-Activated B Cells

    Eisei Kondo;Max S. Topp;Hans Peter Kiem;Yuichi Obata

  • Expression and amplification of myc gene family in small cell lung cancer and its relation to biological characteristics.

    T Takahashi;Y Obata;Y Sekido;T Hida

  • A Proximal κB Site in the IL-23 p19 Promoter Is Responsible for RelA- and c-Rel-Dependent Transcription

    Setsuko Mise-Omata;Etsushi Kuroda;Junko Niikura;Uki Yamashita

  • Repression of Bleomycin-Induced Pneumopathy by TNF

    Misuzu Kuroki;Yuji Noguchi;Michihide Shimono;Kazunori Tomono

  • The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains.

    Toyoyuki Takada;Toshinobu Ebata;Hideki Noguchi;Thomas M. Keane

  • p300/CBP-Dependent and -Independent Transcriptional Interference between NF-κB RelA and p53

    Akiko Ikeda;Xiangao Sun;Yan Li;Yong Kang Zhang

  • Spermatozoa and spermatids retrieved from frozen reproductive organs or frozen whole bodies of male mice can produce normal offspring

    Narumi Ogonuki;Keiji Mochida;Hiromi Miki;Kimiko Inoue

Frequent Co-Authors

Toshitada Takahashi
Toshitada Takahashi Nagoya University
Kevin C K Lloyd
Kevin C K Lloyd University of California, Davis
Kazuo Moriwaki
Kazuo Moriwaki National Institute of Genetics
Toshihiko Shiroishi
Toshihiko Shiroishi National Institute of Genetics
Daniel J. Garry
Daniel J. Garry University of Minnesota
Colin McKerlie
Colin McKerlie Hospital for Sick Children
Satoru Takahashi
Satoru Takahashi University of Tsukuba
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich
David J. Adams
David J. Adams Wellcome Sanger Institute

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