World's Best Scientists 2026 revealed!
Toshitada Takahashi

Toshitada Takahashi

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12286
World Ranking
10917
National Ranking
746

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Antibody

Toshitada Takahashi mainly investigates Immunology, Molecular biology, Antigen, Pathology and Cell culture. His studies deal with areas such as Cytotoxic T cell, CD40 and Lung cancer as well as Immunology. His Molecular biology research incorporates themes from Tumor necrosis factor alpha, In vitro, Northern blot, Knockout mouse and RELA.

His work carried out in the field of Antigen brings together such families of science as Cancer, Antibody and Tissue culture. His Pathology research is multidisciplinary, incorporating elements of Respiratory disease, Gene rearrangement and Acute leukemia. His work deals with themes such as BALB/c, Sarcoma and Virology, which intersect with Cell culture.

His most cited work include:

  • Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells. (369 citations)
  • Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality (264 citations)
  • p53 Mutations in Non-Small Cell Lung Cancer in Japan: Association between Mutations and Smoking (247 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Antigen, Molecular biology, Immunology, Pathology and Cytotoxic T cell. His Antigen study combines topics in areas such as Cell culture, Virology, Leukemia and Antibody, Monoclonal antibody. His Antibody study combines topics from a wide range of disciplines, such as Cancer and In vivo.

As a part of the same scientific family, he mostly works in the field of Molecular biology, focusing on Complementary DNA and, on occasion, Nucleic acid sequence. In his study, Tumor suppressor gene is strongly linked to Cancer research, which falls under the umbrella field of Immunology. Toshitada Takahashi combines subjects such as T cell, Human leukocyte antigen and CD8 with his study of Cytotoxic T cell.

He most often published in these fields:

  • Antigen (41.08%)
  • Molecular biology (40.00%)
  • Immunology (22.16%)

What were the highlights of his more recent work (between 2005-2015)?

  • Antigen (41.08%)
  • Cytotoxic T cell (18.92%)
  • Epitope (14.05%)

In recent papers he was focusing on the following fields of study:

Toshitada Takahashi mostly deals with Antigen, Cytotoxic T cell, Epitope, Minor histocompatibility antigen and Immunology. The Antigen study combines topics in areas such as T cell, Antigen presentation and Antibody, Monoclonal antibody. His Cytotoxic T cell study incorporates themes from Molecular biology, Hematopoietic stem cell transplantation and CD8.

His Molecular biology research focuses on CD28 and how it relates to T-cell receptor and Clone. Toshitada Takahashi combines subjects such as CTL* and Antigen-presenting cell with his study of Epitope. His Immunology study frequently draws connections between related disciplines such as G alpha subunit.

Between 2005 and 2015, his most popular works were:

  • Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells. (168 citations)
  • Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen (93 citations)
  • Effective induction of anti-tumor immune responses with oligomannose-coated liposome targeting to intraperitoneal phagocytic cells. (53 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Immune system

The scientist’s investigation covers issues in Minor histocompatibility antigen, Antigen, Immunology, Transplantation and Human leukocyte antigen. His research investigates the link between Minor histocompatibility antigen and topics such as CTL* that cross with problems in Molecular biology. His Immunology study frequently intersects with other fields, such as Cancer research.

His work carried out in the field of Cancer research brings together such families of science as IL-2 receptor, Streptamer, CD154, CD8 and Adoptive cell transfer. His studies deal with areas such as Virology, Immunogenicity, Gene mapping, Locus and Single-nucleotide polymorphism as well as Transplantation. His study explores the link between Human leukocyte antigen and topics such as Epitope that cross with problems in Cytotoxic T cell.

Best Publications

  • Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

    Hidemasa Goto;Yasuko Tomono;Kozo Ajiro;Hidetaka Kosako

  • Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells.

    Thomas E. Carey;Toshitada Takahashi;Lois A. Resnick;Herbert F. Oettgen

  • Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

    Takahiro S. Doi;Michael W. Marino;Toshitada Takahashi;Toshimichi Yoshida

  • Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers

    Kosaku Uchida;Masaaki Nagatake;Hirotaka Osada;Yasushi Yatabe

  • Autophosphorylation of a Newly Identified Site of Aurora-B Is Indispensable for Cytokinesis

    Yoshihiro Yasui;Takeshi Urano;Aie Kawajiri;Koh Ichi Nagata

  • Cell surface antigens of chemically induced sarcomas of the mouse. I. Murine leukemia virus-related antigens and alloantigens on cultured fibroblasts and sarcoma cells: description of a unique antigen on BALB/c Meth A sarcoma.

    Albert B. DeLEO;Hiroshi Shiku;Toshitada Takahashi;Mary John

  • Cell surface antigens of human malignant melanoma. II. Serological typing with immune adherence assays and definition of two new surface antigens.

    H Shiku;T Takahashi;H F Oettgen

  • Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells.

    H Shiku;P Kisielow;M A Bean;T Takahashi

  • Preferential Expression of c-kit Protooncogene Transcripts in Small Cell Lung Cancer

    Yoshitaka Sekido;Yuichi Obata;Ryuzo Ueda;Toyoaki Hida

  • Serological analysis of cell surface antigens of malignant human brain tumors.

    Michael Pfreundschuh;Hiroshi Shiku;Toshitada Takahashi;Ryuzo Ueda

  • Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells.

    Takashi Akazawa;Takashi Ebihara;Manabu Okuno;Yu Okuda

  • Search for Mutations and Examination of Allelic Expression Imbalance of the p73 Gene at 1p36.33 in Human Lung Cancers

    Shuji Nomoto;Nobuhiro Haruki;Masashi Kondo;Hiroyuki Konishi

  • CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia: a distinct hematolymphoid disease entity.

    Ritsuro Suzuki;Kazuhito Yamamoto;Masao Seto;Yoshitoyo Kagami

  • Immunoglobulin and other surface antigens of cells of the immune system.

    Toshitada Takahashi;Lloyd J. Old;K. Robert McIntire;Edward A. Boyse

  • Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

    Hiroyasu Inada;Ichiro Izawa;Miwako Nishizawa;Eriko Fujita

  • Dynamic property of intermediate filaments: Regulation by phosphorylation

    Masaki Inagaki;Yoichiro Matsuoka;Kunio Tsujimura;Shoji Ando

  • Cell surface antigens of human renal cancer defined by autologous typing.

    R Ueda;H Shiku;M Pfreundschuh;T Takahashi

  • Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients

    Shuta Tomida;Katsumi Koshikawa;Yasushi Yatabe;Tomoko Harano

  • Expression of cancer/testis (CT) antigens in lung cancer.

    Kouhei Tajima;Yuichi Obata;Hiromi Tamaki;Masahiro Yoshida

  • Significant Growth Inhibition of Human Lung Cancer Cells Both in Vitro and in Vivo by the Combined Use of a Selective Cyclooxygenase 2 Inhibitor, JTE-522, and Conventional Anticancer Agents

    Toyoaki Hida;Ken ichi Kozaki;Hidemi Ito;Osamu Miyaishi

Frequent Co-Authors

Ryuzo Ueda
Ryuzo Ueda Nagoya University
Masao Seto
Masao Seto Kurume University
Takashi Takahashi
Takashi Takahashi Nagoya University
Yasuo Morishima
Yasuo Morishima Aichi Medical University
Yasushi Yatabe
Yasushi Yatabe Nagoya University
Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Shigeo Nakamura
Shigeo Nakamura Nagoya University
Hiroshi Shiku
Hiroshi Shiku Mie University
Tetsuya Mitsudomi
Tetsuya Mitsudomi Kindai University

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