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Koichi Kokame

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
10843
World Ranking
16104
National Ranking
1148

Koichi Kokame publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Koichi Kokame sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 177 publications — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Koichi Kokame D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Koichi Kokame sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 53 D-Index — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Koichi Kokame is affiliated with the National Cerebral and Cardiovascular Center in Japan. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with a particular focus on hematology, genetics, immunology, cell biology, and cardiology and cardiovascular medicine.

The scientist's work covers several main topics, including:

  • Complement system in diseases
  • Platelet disorders and treatments
  • Blood coagulation and thrombosis mechanisms
  • Coagulation, bradykinin, polyphosphates, and angioedema
  • Blood groups and transfusion
  • Cellular transport and secretion
  • Erythrocyte function and pathophysiology

Koichi Kokame has contributed to various academic journals, with frequent publications in:

  • Research and Practice in Thrombosis and Haemostasis
  • Japanese Journal of Thrombosis and Hemostasis
  • Journal of Thrombosis and Haemostasis
  • Blood Advances
  • bioRxiv (Cold Spring Harbor Laboratory)

Significant recent papers include:

  • Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan 2023, published in International Journal of Hematology (2023)
  • Derlin-3 Is Required for Changes in ERAD Complex Formation under ER Stress, published in International Journal of Molecular Sciences (2020)
  • Success and limitations of plasma treatment in pregnant women with congenital thrombotic thrombocytopenic purpura, published in Journal of Thrombosis and Haemostasis (2020)
  • Current prophylactic plasma infusion protocols do not adequately prevent long-term cumulative organ damage in the Japanese congenital thrombotic thrombocytopenic purpura cohort, published in British Journal of Haematology (2021)
  • von Willebrand factor Ristocetin co-factor activity to von Willebrand factor antigen level ratio for diagnosis of acquired von Willebrand syndrome caused by aortic stenosis, published in Research and Practice in Thrombosis and Haemostasis (2023)

Koichi Kokame collaborates regularly with several researchers, including:

  • Masanori Matsumoto
  • Yuka Eura
  • Toshiyuki Miyata
  • Keiko Maruyama
  • Kazuya Sakai

Best Publications

  • FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay.

    Koichi Kokame;Yuko Nobe;Yoshihiro Kokubo;Akira Okayama

  • Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes

    Koichi Kokame;Hisao Kato;Toshiyuki Miyata

  • Differential Contributions of ATF6 and XBP1 to the Activation of Endoplasmic Reticulum Stress-Responsive cis -Acting Elements ERSE, UPRE and ERSE-II

    Keisuke Yamamoto;Hiderou Yoshida;Hiderou Yoshida;Koichi Kokame;Randal J. Kaufman

  • Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity

    Koichi Kokame;Masanori Matsumoto;Kenji Soejima;Hideo Yagi

  • Herp, a New Ubiquitin-like Membrane Protein Induced by Endoplasmic Reticulum Stress

    Koichi Kokame;Kishan Lal Agarwala;Hisao Kato;Toshiyuki Miyata

  • Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured rat-1 fibroblasts

    Tsuyoshi Hirota;Toshiyuki Okano;Koichi Kokame;Hiroko Shirotani-Ikejima

  • Identification of ERSE-II, a New cis-Acting Element Responsible for the ATF6-dependent Mammalian Unfolded Protein Response

    Koichi Kokame;Hisao Kato;Toshiyuki Miyata

  • Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus.

    Yukari Date;Takuya Shimbara;Shuichi Koda;Koji Toshinai

  • Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart.

    Rui-Hai Zhou;Koichi Kokame;Yoshitane Tsukamoto;Chikao Yutani

  • Lipid modification at the N terminus of photoreceptor G-protein α-subunit

    Koichi Kokame;Yoshitaka Fukada;Tôru Yoshizawa;Toshifumi Takao

  • Evolution of the androgen receptor pathway during progression of prostate cancer.

    Peter J.M. Hendriksen;Natasja F.J. Dits;Koichi Kokame;Antoine Veldhoven

  • Natural history of Upshaw-Schulman syndrome based on ADAMTS13 gene analysis in Japan.

    Y. Fujimura;M. Matsumoto;A. Isonishi;H. Yagi

  • ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage.

    Kenji Soejima;Masanori Matsumoto;Koichi Kokame;Hideo Yagi

  • VWF73, a region from D1596 to R1668 of von Willebrand factor, provides a minimal substrate for ADAMTS-13.

    Koichi Kokame;Masanori Matsumoto;Yoshihiro Fujimura;Toshiyuki Miyata

  • Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura

    Fumiaki Banno;Koichi Kokame;Tomohiko Okuda;Shigenori Honda

  • Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome

    Masanori Matsumoto;Koichi Kokame;Kenji Soejima;Masayoshi Miura

  • Pregnancy‐induced thrombocytopenia and TTP, and the risk of fetal death, in Upshaw–Schulman syndrome: a series of 15 pregnancies in 9 genotyped patients

    Yoshihiro Fujimura;Masanori Matsumoto;Koichi Kokame;Ayami Isonishi

  • Ndrg1-Deficient Mice Exhibit a Progressive Demyelinating Disorder of Peripheral Nerves

    Tomohiko Okuda;Yujiro Higashi;Koichi Kokame;Chihiro Tanaka

  • Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor

    Masashi Akiyama;Soichi Takeda;Koichi Kokame;Junichi Takagi

  • Luman/CREB3 Induces Transcription of the Endoplasmic Reticulum (ER) Stress Response Protein Herp through an ER Stress Response Element

    Genqing Liang;Timothy E. Audas;Yu Li;Gregory P. Cockram

Frequent Co-Authors

Toshiyuki Miyata
Toshiyuki Miyata Kyushu University
Masashi Akiyama
Masashi Akiyama Nagoya University
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Bernhard Lämmle
Bernhard Lämmle University of Bern
Masaomi Nangaku
Masaomi Nangaku University of Tokyo
Kenji Kangawa
Kenji Kangawa National Cerebral and Cardiovascular Center
Yasuo Ikeda
Yasuo Ikeda Waseda University
Yoshitaka Fukada
Yoshitaka Fukada University of Tokyo
Sergio Lavandero
Sergio Lavandero University of Chile
Michihiro Fujiwara
Michihiro Fujiwara Fukuoka University

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Best Scientists Citing Koichi Kokame

Bernhard Lämmle

Bernhard Lämmle

University of Bern

Publications: 53

Karen Vanhoorelbeke

Karen Vanhoorelbeke

KU Leuven

Publications: 49

Flora Peyvandi

Flora Peyvandi

University of Milan

Publications: 44

Toshiyuki Miyata

Toshiyuki Miyata

Kyushu University

Publications: 37

James N. George

James N. George

University of Oklahoma Health Sciences Center

Publications: 36

Denisa D. Wagner

Denisa D. Wagner

Boston Children's Hospital

Publications: 25

Kazuyoshi Tsutsui

Kazuyoshi Tsutsui

Hiroshima University

Publications: 24

Jan Voorberg

Jan Voorberg

University of Amsterdam

Publications: 23

Randal J. Kaufman

Randal J. Kaufman

Sanford Burnham Prebys Medical Discovery Institute

Publications: 22

David Lane

David Lane

Imperial College London

Publications: 19

Peter J. Lenting

Peter J. Lenting

University of Paris-Saclay

Publications: 17

Bernhard Nieswandt

Bernhard Nieswandt

University of Würzburg

Publications: 17

Des R. Richardson

Des R. Richardson

Griffith University

Publications: 15

Christoph Kleinschnitz

Christoph Kleinschnitz

University of Duisburg-Essen

Publications: 14

Richard C. Austin

Richard C. Austin

McMaster University

Publications: 14

Yuzuru Kanakura

Yuzuru Kanakura

Osaka University

Publications: 14

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