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Alcmène Chalazonitis

Alcmène Chalazonitis

D-Index & Metrics

Neuroscience

D-Index
32
Citations
5225
World Ranking
9507
National Ranking
4016

Overview

Alcmène Chalazonitis is affiliated with Columbia University in the United States and has contributed to the field of medicine with a strong focus on congenital gastrointestinal and neural anomalies as well as gastrointestinal motility and disorders. Their recent research spans overlapping subfields including surgery, gastroenterology, psychiatry and mental health, neurology, and pharmacy.

The scientist's work has been published across several notable venues. These include:

  • The Journal of Comparative Neurology (2 publications)
  • npj Parkinson s Disease (1 publication)
  • American Journal of Physiology-Gastrointestinal and Liver Physiology (1 publication)

Key papers authored or co-authored by Chalazonitis showcase the focus on neural factors influencing gastrointestinal function and neurological disease mechanisms. These papers include:

  • "Cerebral dopamine neurotrophic factor is essential for enteric neuronal development, maintenance, and regulation of gastrointestinal transit", 2020, The Journal of Comparative Neurology
  • "Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson's disease", 2022, npj Parkinson s Disease
  • "Contribution of neuroligin and neurexin alternative splicing to the establishment of enteric neuronal synaptic specificity", 2025, American Journal of Physiology-Gastrointestinal and Liver Physiology
  • "Cover Image, Volume 528, Issue 14", 2020, The Journal of Comparative Neurology

Research topics addressed in Chalazonitis's body of work include:

  • Congenital gastrointestinal and neural anomalies
  • Gastrointestinal motility and disorders
  • Child nutrition and feeding issues
  • Parkinson's disease mechanisms and treatments
  • Infant health and development

They frequently collaborate with other scholars, with notable coauthors being:

  • Michael D. Gershon
  • ZhiShan Li
  • Meenakshi Rao
  • Päivi Lindholm
  • Märt Saarma

Alcmène Chalazonitis's multidisciplinary approach intersects surgical methods with neurogastroenterological research, contributing to a better understanding of neural specificity in enteric systems and mechanisms underlying gastrointestinal and neurological diseases.

Best Publications

  • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

    Makiko Nagai;Diane B Re;Tetsuya Nagata;Alcmène Chalazonitis

  • Essential Roles of Enteric Neuronal Serotonin in Gastrointestinal Motility and the Development/Survival of Enteric Dopaminergic Neurons

    Zhishan Li;Alcmène Chalazonitis;Yung-yu Huang;J. John Mann

  • Age-dependent differences in the effects of GDNF and NT-3 on the development of neurons and glia from neural crest-derived precursors immunoselected from the fetal rat gut: expression of GFRalpha-1 in vitro and in vivo.

    Alcmène Chalazonitis;Taube P Rothman;Jingxian Chen;Michael D Gershon

  • Transforming growth factor β has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor

    Alcmène Chalazonitis;Jacqueline Kalberg;Daniel R. Twardzik;Richard S. Morrison

  • Neurotrophin-3 induces neural crest-derived cells from fetal rat gut to develop in vitro as neurons or glia

    A Chalazonitis;TP Rothman;J Chen;F Lamballe

  • Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit.

    Alcmène Chalazonitis;Tuan D. Pham;Zhishan Li;Daniel Roman

  • Bone Morphogenetic Protein-2 and -4 Limit the Number of Enteric Neurons But Promote Development of a TrkC-Expressing Neurotrophin-3-Dependent Subset

    Alcmène Chalazonitis;Fabien D'Autréaux;Udayan Guha;Tuan D. Pham

  • Enteric nervous system manifestations of neurodegenerative disease.

    Alcmène Chalazonitis;Meenakshi Rao

  • Elevated potassium induces morphological differentiation of dorsal root ganglionic neurons in dissociated cell culture.

    Alcmène Chalazonitis;Gerald D. Fischbach

  • Neurotrophin-3 Is Required for the Survival–Differentiation of Subsets of Developing Enteric Neurons

    Alcmène Chalazonitis;Tuan D. Pham;Taube P. Rothman;Peter S. DiStefano

  • Enteric Neuronal Density Contributes to the Severity of Intestinal Inflammation

    Kara Gross Margolis;Korey Stevanovic;Nima Karamooz;Zi Shan Li

  • The alpha1 subunit of laminin-1 promotes the development of neurons by interacting with LBP110 expressed by neural crest-derived cells immunoselected from the fetal mouse gut.

    Alcmène Chalazonitis;Virginia M. Tennyson;Maura C. Kibbey;Taube P. Rothman

  • Promotion of the development of enteric neurons and glia by neuropoietic cytokines: Interactions with neurotrophin-3

    Alcmène Chalazonitis;Taube P. Rothman;Jingxian Chen;Emily N. Vinson

  • Neurotrophin-3 in the development of the enteric nervous system.

    Alcmène Chalazonitis

  • Transforming growth factor alpha, but not epidermal growth factor, promotes the survival of sensory neurons in vitro

    Alcmène Chalazonitis;John A. Kessler;Daniel R. Twardzik;Richard S. Morrison

  • Bone morphogenetic proteins regulate enteric gliogenesis by modulating ErbB3 signaling.

    Alcmène Chalazonitis;Fabien D'Autréaux;Fabien D'Autréaux;Tuan D. Pham;John A. Kessler

  • Opioids excite rather than inhibit sensory neurons after chronic opioid exposure of spinal cord-ganglion cultures

    S.M. Crain;K.-F. Shen;A. Chalazonitis

  • Inhibitor of cyclic AMP-dependent protein kinase blocks opioid-induced prolongation of the action potential of mouse sensory ganglion neurons in dissociated cell cultures.

    Guo-Guang Chen;Alcmene Chalazonitis;Ke-Fei Shen;Stanley M. Crain

  • Neural crest-derived cells isolated from the gut by immunoselection develop neuronal and glial phenotypes when cultured on laminin.

    Howard D. Pomeranz;Taube P. Rothman;Alcmène Chalazonitis;Virginia M. Tennyson

  • Nerve growth factor regulates the action potential duration of mature sensory neurons

    Alcmene Chalazonitis;Edith R. Peterson;Stanley M. Crain

  • Purine analogs inhibit nerve growth factor-promoted neurite outgrowth by sympathetic and sensory neurons

    Lloyd A. Greene;Cinzia Volonté;Alcmène Chalazonitis

  • Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.

    Alcmène Chalazonitis;Amy A. Tang;Yulei Shang;Tuan D. Pham

  • Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.

    Z Li;A. Chalazonitis;Y Y Huang;J. Mann

Frequent Co-Authors

Mart Saarma
Mart Saarma University of Helsinki
Cinzia Volonté
Cinzia Volonté Fondazione Santa Lucia
Mark Bothwell
Mark Bothwell University of Washington
Mikko Airavaara
Mikko Airavaara University of Helsinki
Peter Scheiffele
Peter Scheiffele University of Basel
Hynek Wichterle
Hynek Wichterle Columbia University
Thomas M. Jessell
Thomas M. Jessell Columbia University
Serge Przedborski
Serge Przedborski Columbia University

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