World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
23535
World Ranking
5254
National Ranking
405

Research.com Recognitions

  • 2018 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Vassilis Pachnis is affiliated with The Francis Crick Institute in the United Kingdom. Their research centers on the intersection of medicine, biochemistry, genetics, and molecular biology, with particular focus on molecular biology and surgery. The scientist explores topics related to congenital gastrointestinal and neural anomalies, gastrointestinal motility and disorders, digestive system health, neurogenesis and neuroplasticity mechanisms, diet and metabolism studies, gut microbiota, and congenital heart defects research.

Recent publications by Vassilis Pachnis include:

  • Neuronal programming by microbiota regulates intestinal physiology, 2020, Nature
  • Regulation of intestinal immunity and tissue repair by enteric glia, 2021, Nature
  • Boundaries and integration between microbiota, the nervous system, and immunity, 2023, Immunity
  • Enteric glia as a source of neural progenitors in adult zebrafish, 2020, eLife
  • The role of enteric glia in intestinal immunity, 2022, Current Opinion in Immunology

Frequent co-authors collaborating with Pachnis include Yuuki Obata, Stefan Boeing, Anna Laddach, Ana Carina Bon-Frauches, and Fränze Progatzky.

Publications are often featured in journals and platforms such as Nature, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cell, and Research Square.

The scientist has been recognized with several honors, including being named a Fellow of the Royal Society in the United Kingdom in 2018. Additionally, they are a Fellow of The Academy of Medical Sciences in the United Kingdom and a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

    Anita Schuchardt;Vivette D'Agati;Lena Larsson-Blomberg;Frank Costantini

  • Expression of the c-ret proto-oncogene during mouse embryogenesis

    Vassilis Pachnis;Baljinder Mankoo;Frank Costantini

  • GDNF signalling through the Ret receptor tyrosine kinase

    Pascale Durbec;Camelia V. Marcos-Gutierrez;Carol Kilkenny;Maria Grigoriou

  • Functional receptor for GDNF encoded by the c-ret proto-oncogene.

    Miles Trupp;Ernest Arenas;Michael Fainzilber;Ann-Sofie Nilsson

  • The Medial Ganglionic Eminence Gives Rise to a Population of Early Neurons in the Developing Cerebral Cortex

    Alexandros A. Lavdas;Maria Grigoriou;Vassilis Pachnis;John G. Parnavelas

  • Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies.

    Tiffany A. Heanue;Vassilis Pachnis

  • Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts.

    Pascale L. Durbec;Lena B. Larsson-Blomberg;Anita Schuchardt;Frank Costantini

  • Spatial Genetic Patterning of the Embryonic Neuroepithelium Generates GABAergic Interneuron Diversity in the Adult Cortex

    Matthew Fogarty;Matthew Grist;Diego Gelman;Oscar Marín

  • Glial origin of mesenchymal stem cells in a tooth model system

    Nina Kaukua;Maryam Khatibi Shahidi;Chrysoula Konstantinidou;Vyacheslav Dyachuk

  • Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis

    Dipa Natarajan;Camelia Marcos-Gutierrez;Camelia Marcos-Gutierrez;Vassilis Pachnis;Esther de Graaff;Esther de Graaff

  • Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury

    Catia Laranjeira;Katarina Sandgren;Nicoletta Kessaris;William Richardson

  • Lhx6 Activity Is Required for the Normal Migration and Specification of Cortical Interneuron Subtypes

    Petros Liodis;Myrto Denaxa;Marirena Grigoriou;Cynthia Akufo-Addo

  • Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium.

    Kirsi Sainio;Petro Suvanto;Jamie Davies;Jorma Wartiovaara

  • Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development

    Maria Grigoriou;Abigail S. Tucker;Paul T. Sharpe;Vassilis Pachnis

  • Microbiota Controls the Homeostasis of Glial Cells in the Gut Lamina Propria

    Panagiotis S. Kabouridis;Panagiotis S. Kabouridis;Reena Lasrado;Sarah McCallum;Song Hui Chng;Song Hui Chng

  • Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes

    Vassilis Pachnis;Alexandra Belayew;Shirley M. Tilghman

  • Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development.

    A. Schuchardt;V. D'Agati;V. Pachnis;F. Costantini

  • Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis

    E de Graaff;S Srinivas;C Kilkenny;V D'Agati

  • Enteric Nervous System Progenitors Are Coordinately Controlled by the G Protein-Coupled Receptor EDNRB and the Receptor Tyrosine Kinase RET

    Amanda Barlow;Esther de Graaff;Vassilis Pachnis

  • Tyrosine kinase receptor RET is a key regulator of Peyer’s Patch organogenesis

    Henrique Veiga-Fernandes;Mark C. Coles;Katie E. Foster;Amisha Patel

Frequent Co-Authors

Frank Costantini
Frank Costantini Columbia University
Nicoletta Kessaris
Nicoletta Kessaris University College London
Dimitris Kioussis
Dimitris Kioussis Medical Research Council
Vivette D. D'Agati
Vivette D. D'Agati Columbia University
Juan Burrone
Juan Burrone King's College London
Erik Sundström
Erik Sundström Karolinska Institute
Paul T. Sharpe
Paul T. Sharpe King's College London
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Mark Coles
Mark Coles University of Oxford
Stanislas Lyonnet
Stanislas Lyonnet Université Paris Cité

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