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Dominique Guehl

Dominique Guehl

D-Index & Metrics

Neuroscience

D-Index
48
Citations
7538
World Ranking
6243
National Ranking
276

Overview

Dominique Guehl is affiliated with the University of Bordeaux in France and focuses on research in medicine and neuroscience, particularly in the areas of neurology and cellular and molecular neuroscience. Their work spans several specialized subfields including cognitive neuroscience, psychiatry and mental health, and molecular biology.

The scientist's research predominantly addresses neurological disorders and treatments, with significant emphasis on Parkinson's disease mechanisms and therapies. Other notable topics include genetic neurodegenerative diseases, botulinum toxin and related neurological disorders, transcranial magnetic stimulation studies, and neuroscience combined with neuropharmacology and neural engineering.

Dominique Guehl has co-authored numerous publications with frequent collaborators such as Pierre Burbaud, Isabelle Bénatru, Emmanuel Cuny, Mélissa Tir, and Edouard Courtin.

They have contributed to research published mainly in venues such as Clinical Neurophysiology, Brain Stimulation, Revue Neurologique, Brain, and the Journal of Parkinson's Disease.

Representative recent papers include:

  • A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease, 2023, Nature Medicine
  • A Phase 2 Randomized Trial of Asleep versus Awake Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease, 2020, Stereotactic and Functional Neurosurgery
  • Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia, 2020, Brain
  • Trial of Botulinum Toxin for Isolated or Essential Head Tremor, 2023, New England Journal of Medicine
  • Ancestral persistence of vestibulospinal reflexes in axial muscles in humans, 2020, Journal of Neurophysiology

Best Publications

  • Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.

    Matthieu F. Bastide;Wassilios G. Meissner;Barbara Picconi;Stefania Fasano

  • Pathophysiology of obsessive-compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology.

    Bruno Aouizerate;Dominique Guehl;Emmanuel Cuny;Alain Rougier

  • Deep brain stimulation of the ventral caudate nucleus in the treatment of obsessive—compulsive disorder and major depression: Case report

    Bruno Aouizerate;Emmanuel Cuny;Corinne Martin-Guehl;Dominique Guehl

  • Meta-analysis of brain volume changes in obsessive-compulsive disorder.

    Jean-Yves Rotge;Dominique Guehl;Bixente Dilharreguy;Jean Tignol

  • Provocation of obsessive-compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies.

    Jean-Yves Rotge;Dominique Guehl;Bixente Dilharreguy;Emmanuel Cuny

  • High-frequency stimulation of the globus pallidus internalis in Parkinson's disease: a study of seven cases

    Christian Gross;Alain Rougier;Dominique Guehl;Thomas Boraud

  • Gray Matter Alterations in Obsessive–Compulsive Disorder: An Anatomic Likelihood Estimation Meta-Analysis

    Jean-Yves Rotge;Nicolas Langbour;Dominique Guehl;Bernard Bioulac

  • Methylphenidate for gait hypokinesia and freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel, randomised, placebo-controlled trial

    Caroline Moreau;Arnaud Delval;Luc Defebvre;Kathy Dujardin

  • Effects of L-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey.

    Th Boraud;E Bezard;D Guehl;B Bioulac

  • Thalamic Neuronal Activity in Dopamine-Depleted Primates: Evidence for a Loss of Functional Segregation within Basal Ganglia Circuits

    Mathias Pessiglione;Dominique Guehl;Anne-Sophie Rolland;Chantal François

  • Lack of agreement between direct magnetic resonance imaging and statistical determination of a subthalamic target: the role of electrophysiological guidance

    Emmanuel Cuny;Dominique Guehl;Pierre Burbaud;Christian Gross

  • Clinical and economic results of bilateral subthalamic nucleus stimulation in Parkinson’s disease

    V Fraix;J-L Houeto;C Lagrange;C Le Pen

  • Parkinson's disease patients with bilateral subthalamic deep brain stimulation gain weight

    Frédéric Macia;Caroline Perlemoine;Irène Coman;Dominique Guehl

  • Dynamics of Parkinsonian tremor during deep brain stimulation.

    Michèle S. Titcombe;Leon Glass;Dominique Guehl;Anne Beuter

  • Distinct striatal targets in treating obsessive-compulsive disorder and major depression.

    Bruno Aouizerate;Emmanuel Cuny;Eric Bardinet;Jerome Yelnik

  • A functional magnetic resonance imaging study of mental subtraction in human subjects

    Pierre Burbaud;Olivier Camus;D. Guehl;Bernard Bioulac

  • Tremor-related activity of neurons in the 'motor' thalamus: changes in firing rate and pattern in the MPTP vervet model of parkinsonism.

    D Guehl;M Pessiglione;C François;J Yelnik

  • Neuronal correlates of obsessions in the caudate nucleus.

    Dominique Guehl;Abdelhamid Benazzouz;Bruno Aouizerate;Emmanuel Cuny

  • Deep brain stimulation for OCD and major depression.

    Bruno Aouizerate;Corinne Martin-Guehl;Emmanuel Cuny;Dominique Guehl

  • Minimal tissue damage after stimulation of the motor thalamus in a case of chorea-acanthocytosis.

    P. Burbaud;A. Vital;A. Rougier;S. Bouillot

  • A systematic review of studies on anatomical position of electrode contacts used for chronic subthalamic stimulation in Parkinson’s disease

    François Caire;Danièle Ranoux;Dominique Guehl;Pierre Burbaud

Frequent Co-Authors

Pierre Burbaud
Pierre Burbaud University of Bordeaux
Bernard Bioulac
Bernard Bioulac University of Bordeaux
François Tison
François Tison University of Bordeaux
Michèle Allard
Michèle Allard Centre national de la recherche scientifique, CNRS
Wassilios G. Meissner
Wassilios G. Meissner University of Bordeaux
Abdelhamid Benazzouz
Abdelhamid Benazzouz University of Bordeaux
Christian E. Gross
Christian E. Gross University of Bordeaux
Stéphane Thobois
Stéphane Thobois Hospices Civils de Lyon
Philippe Damier
Philippe Damier Grenoble Alpes University

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