John F. Hunt

What is he best known for?

The fields of study he is best known for:

• Enzyme
• Gene
• DNA

John F. Hunt spends much of his time researching Biochemistry, Protein structure, Nucleotide, Stereochemistry and ATP-binding cassette transporter. As part of his studies on Biochemistry, John F. Hunt often connects relevant subjects like Biophysics. His Protein structure research is multidisciplinary, incorporating perspectives in Computational biology, Protein Data Bank, Cystic fibrosis transmembrane conductance regulator and Protein folding.

His Cystic fibrosis transmembrane conductance regulator study combines topics in areas such as Cyclic nucleotide-binding domain and Cell biology. He has researched Nucleotide in several fields, including Nucleic acid and Active site. He interconnects Transport protein and Transmembrane protein in the investigation of issues within Stereochemistry.

His most cited work include:

• ATP Binding to the Motor Domain from an ABC Transporter Drives Formation of a Nucleotide Sandwich Dimer. (688 citations)
• Protein production and purification. (655 citations)
• Glycophorin A dimerization is driven by specific interactions between transmembrane alpha helices (410 citations)

What are the main themes of his work throughout his whole career to date?

John F. Hunt mostly deals with Biochemistry, Protein structure, Crystallography, Stereochemistry and Structural genomics. His study brings together the fields of Biophysics and Biochemistry. His Protein structure study integrates concerns from other disciplines, such as Transport protein, Plasma protein binding, Cyclic nucleotide-binding domain, Structural biology and Binding site.

The concepts of his Crystallography study are interwoven with issues in Protein tertiary structure and Nuclear magnetic resonance spectroscopy. The Stereochemistry study combines topics in areas such as Lyase, Cofactor, Active site, Dimer and Molecule. His Structural genomics research also works with subjects such as

• Computational biology together with Genetics and Genomics,
• Bioinformatics, which have a strong connection to Crystallization.

He most often published in these fields:

• Biochemistry (48.21%)
• Protein structure (23.81%)
• Crystallography (18.45%)

What were the highlights of his more recent work (between 2010-2021)?

• Biochemistry (48.21%)
• Protein structure (23.81%)
• Crystallography (18.45%)

In recent papers he was focusing on the following fields of study:

John F. Hunt focuses on Biochemistry, Protein structure, Crystallography, Genetics and Cell biology. His Biochemistry research integrates issues from In vivo and Solubility. His study in Protein structure is interdisciplinary in nature, drawing from both Plasma protein binding, ATP hydrolysis, Active site, Structural biology and Protein engineering.

His studies deal with areas such as Protein sequencing, Protein tertiary structure, Macromolecular crystallography and Epitope as well as Crystallography. His work carried out in the field of Genetics brings together such families of science as Computational biology and Data science. His Cell biology research is multidisciplinary, relying on both Biogenesis, Membrane protein and Ribosomal protein.

Between 2010 and 2021, his most popular works were:

• Codon influence on protein expression in E. coli correlates with mRNA levels (239 citations)
• The COMBREX Project: Design, Methodology, and Initial Results (135 citations)
• Computational design of catalytic dyads and oxyanion holes for ester hydrolysis. (92 citations)

In his most recent research, the most cited papers focused on:

• Enzyme
• Gene
• Amino acid

John F. Hunt spends much of his time researching Biochemistry, Protein structure, Stereochemistry, Crystallography and Genetics. Translation elongation, Elongation factor, Mutant, Escherichia coli and A-site are the primary areas of interest in his Biochemistry study. As a part of the same scientific family, John F. Hunt mostly works in the field of Protein structure, focusing on Protein engineering and, on occasion, Computational biology, Synthetic biology and Plasma protein binding.

His research in Stereochemistry intersects with topics in Molecule, Catalysis, Active site and Protein design. John F. Hunt combines subjects such as Dimer, Protomer, Site-directed spin labeling and Tetramer with his study of Crystallography. His work on Regulation of gene expression and Genomic databases is typically connected to Project design and Microbial Genes as part of general Genetics study, connecting several disciplines of science.