Motoyuki Otsuka mainly focuses on Virology, Hepatocellular carcinoma, Cancer research, Molecular biology and Genetics. His work carried out in the field of Virology brings together such families of science as Dicer and Small interfering RNA. His work in Small interfering RNA covers topics such as Caenorhabditis elegans which are related to areas like microRNA.
His Hepatocellular carcinoma study is concerned with the field of Internal medicine as a whole. His Cancer research research incorporates themes from Regulator, Inflammation, Knockout mouse and Colitis. Motoyuki Otsuka has included themes like Apoptosis, Transcription factor, Transfection, Reporter gene and Signal transduction in his Molecular biology study.
His main research concerns Cancer research, microRNA, Virology, Molecular biology and Hepatocellular carcinoma. His biological study spans a wide range of topics, including Carcinogenesis, Cancer, Pancreatic cancer and Inflammation, Immunology. His studies examine the connections between microRNA and genetics, as well as such issues in Bioinformatics, with regards to Non-coding RNA.
His research on Virology frequently connects to adjacent areas such as RNA interference. His work investigates the relationship between Molecular biology and topics such as Cell biology that intersect with problems in Tumor necrosis factor alpha and Transcription factor. His studies in Hepatocellular carcinoma integrate themes in fields like Hepatitis C and Genotype.
His primary areas of study are Cancer research, Carcinogenesis, microRNA, Virology and Hepatitis B virus. His studies deal with areas such as Autophagy, Circular RNA, KRAS, KRAS Gene Mutation and Pancreatic cancer as well as Cancer research. His Carcinogenesis study also includes fields such as
As a part of the same scientific family, he mostly works in the field of Hepatocellular carcinoma, focusing on Gastroenterology and, on occasion, Chronic hepatitis. Motoyuki Otsuka combines subjects such as Molecular biology, Regulation of gene expression, Wnt signaling pathway and CpG Island Methylator Phenotype with his study of microRNA. His study in the fields of Viral replication under the domain of Virology overlaps with other disciplines such as cccDNA.
His primary areas of investigation include Carcinogenesis, Cancer research, RNA, microRNA and Hepatitis B virus. His Carcinogenesis research is multidisciplinary, incorporating elements of Proinflammatory cytokine, Molecular biology, Colitis and Dicer. His Cancer research research integrates issues from Histone H3, Histone, Demethylase, Pancreatic cancer and Downregulation and upregulation.
His Downregulation and upregulation research includes elements of Non-coding RNA, Carcinoma and Pancreatic ductal adenocarcinoma. His microRNA study integrates concerns from other disciplines, such as Tumor necrosis factor alpha, Pathogenesis, Hepatocellular carcinoma, Molecular genetics and Human genetics. His Hepatitis B virus study is associated with Virology.
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Correction: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma
Kentaro Kojima;Akemi Takata;Charles Vadnais;Motoyuki Otsuka.
Nature Communications (2012)
Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
Motoyuki Otsuka;Qing Jing;Philippe Georgel;Liguo New.
Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma
Vinod Kumar;Naoya Kato;Yuji Urabe;Atsushi Takahashi.
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice
Motoyuki Otsuka;Min Zheng;Masaaki Hayashi;Jing-Dwan Lee.
Journal of Clinical Investigation (2008)
Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer
Naoya Kato;Hideo Yoshida;Suzane Kioko Ono-nita;Jun Kato.
Full length cdna
Takao Isogai;Tomoyasu Sugiyama;Tetsuji Otsuki;Ai Wakamatsu.
Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease
Tomoyoshi Soga;Masahiro Sugimoto;Masashi Honma;Masayo Mori.
Journal of Hepatology (2011)
Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection
Yue Wang;Naoya Kato;Yujin Hoshida;Hideo Yoshida.
Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability.
Motoyuki Otsuka;Naoya Kato;Keng-Hsin Lan;Hideo Yoshida.
Journal of Biological Chemistry (2000)
Full-length cDNA sequences
Yuri Hio;Ryotaro Irie;Shizuko Ishii;Takao Isogai.
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