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Motoyuki Otsuka

Motoyuki Otsuka

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12428
World Ranking
13784
National Ranking
967

Overview

Motoyuki Otsuka is affiliated with the University of Tokyo in Japan and has an extensive publication record in the field of medicine. Their work primarily focuses on surgery, oncology, pulmonary and respiratory medicine, epidemiology, and molecular biology, reflecting a multidisciplinary approach within medical research.

The scientist's contributions cover a diverse range of research topics, including:

  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Hepatitis B Virus Studies
  • Helicobacter pylori-related gastroenterology studies
  • Esophageal and GI Pathology

Motoyuki Otsuka has co-authored numerous papers with frequent collaborators such as Masaya Iwamuro, Takehiro Tanaka, Kazuyuki Matsumoto, Shigeru Horiguchi, and Koichiro Tsutsumi. The collaboration with these researchers is reflected in multiple high-quality publications over time.

The scientist has published widely in a number of journals, with the following venues being the most common outlets:

  • Cureus
  • Gastrointestinal Endoscopy
  • Hepatology Research
  • Endoscopy
  • Internal Medicine

Recent notable papers authored or co-authored by Motoyuki Otsuka include:

  • Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020, 2021, Journal of Gastroenterology
  • Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020, 2021, Hepatology Research
  • Emerging Roles of Exosomal Circular RNAs in Cancer, 2020, Frontiers in Cell and Developmental Biology
  • HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA, 2021, Journal of Hepatology
  • Impact of Obesity and Heavy Alcohol Consumption on Hepatocellular Carcinoma Development after HCV Eradication with Antivirals, 2021, Liver Cancer

Best Publications

  • Correction: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

    Kentaro Kojima;Akemi Takata;Charles Vadnais;Motoyuki Otsuka

  • Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression

    Motoyuki Otsuka;Qing Jing;Philippe Georgel;Liguo New

  • Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

    Vinod Kumar;Naoya Kato;Yuji Urabe;Atsushi Takahashi

  • Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice

    Motoyuki Otsuka;Min Zheng;Masaaki Hayashi;Jing-Dwan Lee

  • Activation of intracellular signaling by hepatitis B and C viruses: C-viral core is the most potent signal inducer

    Naoya Kato;Hideo Yoshida;Suzane Kioko Ono-nita;Jun Kato

  • Full length cdna

    Takao Isogai;Tomoyasu Sugiyama;Tetsuji Otsuki;Ai Wakamatsu

  • Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease

    Tomoyoshi Soga;Masahiro Sugimoto;Masashi Honma;Masayo Mori

  • Interleukin-1β gene polymorphisms associated with hepatocellular carcinoma in hepatitis C virus infection

    Yue Wang;Naoya Kato;Yujin Hoshida;Hideo Yoshida

  • Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability.

    Motoyuki Otsuka;Naoya Kato;Keng-Hsin Lan;Hideo Yoshida

  • Macrophage Deletion of p38α Partially Impairs Lipopolysaccharide-Induced Cellular Activation

    Young Jun Kang;Jianming Chen;Motoyuki Otsuka;Johann Mols

  • Full-length cDNA sequences

    Yuri Hio;Ryotaro Irie;Shizuko Ishii;Takao Isogai

  • Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription.

    Hiroyoshi Taniguchi;Naoya Kato;Motoyuki Otsuka;Tadashi Goto

  • CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.

    Naoto Fujiwara;Hayato Nakagawa;Kenichiro Enooku;Yotaro Kudo

  • Vitamin K2 inhibits the growth and invasiveness of hepatocellular carcinoma cells via protein kinase A activation

    Motoyuki Otsuka;Naoya Kato;Run Xuan Shao;Yujin Hoshida

  • Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses.

    Motoyuki Otsuka;Naoya Kato;Masaru Moriyama;Hiroyoshi Taniguchi

  • Circulating RNAs as new biomarkers for detecting pancreatic cancer

    Takahiro Kishikawa;Motoyuki Otsuka;Motoko Ohno;Takeshi Yoshikawa

  • Hepatitis C Virus Core Protein Is a Potent Inhibitor of RNA Silencing-Based Antiviral Response

    Yue Wang;Naoya Kato;Amarsanaa Jazag;Narayan Dharel

  • The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels

    Chikako Shibata;Motoko Ohno;Motoyuki Otsuka;Motoyuki Otsuka;Takahiro Kishikawa

  • Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling

    Young Jun Kang;Bo-Ram Bang;Kyung Ho Han;Lixin Hong

  • MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

    Kentaro Kojima;Akemi Takata;Charles Vadnais;Motoyuki Otsuka

Frequent Co-Authors

Kazuhiko Koike
Kazuhiko Koike University of Tokyo
Masao Omata
Masao Omata University of Tokyo
Haruhiko Yoshida
Haruhiko Yoshida University of Tokyo
Yujin Hoshida
Yujin Hoshida The University of Texas Southwestern Medical Center
Takao Kawabe
Takao Kawabe University of Tokyo
Naohiko Seki
Naohiko Seki Chiba University
Yasushi Shiratori
Yasushi Shiratori Okayama University
Jiahuai Han
Jiahuai Han Xiamen University
Tsuneo Ikenoue
Tsuneo Ikenoue University of Tokyo
Hideki Aizaki
Hideki Aizaki National Institutes of Health

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