World's Best Scientists 2026 revealed!

Overview

Christian F. Singer is affiliated with the Medical University of Vienna in Austria. Their research primarily centers on medical and biochemistry fields, focusing on oncology, cancer research, and pulmonary and respiratory medicine.

The main fields of study associated with Singer's work include Medicine and Biochemistry, Genetics and Molecular Biology. More specific subfields include Oncology, Cancer Research, Pulmonary and Respiratory Medicine, Genetics, and Molecular Biology.

Key research topics covered in their publications encompass Breast Cancer Treatment Studies, Advanced Breast Cancer Therapies, BRCA gene mutations in cancer, HER2/EGFR in Cancer Research, Cancer Treatment and Pharmacology, Cancer Genomics and Diagnostics, and Ovarian cancer diagnosis and treatment.

Singer has contributed extensively to scientific literature, with numerous papers published in recognized journals. Some recent notable works include:

  • "ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer" (2021), Annals of Oncology
  • "Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer" (2022), Annals of Oncology
  • "Trastuzumab deruxtecan in HER2-positive breast cancer with brain metastases: a single-arm, phase 2 trial" (2022), Nature Medicine
  • "Adjuvant Palbociclib for Early Breast Cancer: The PALLAS Trial Results (ABCSG-42/AFT-05/BIG-14-03)" (2021), Journal of Clinical Oncology
  • "Understanding breast cancer complexity to improve patient outcomes: The St Gallen International Consensus Conference for the Primary Therapy of Individuals with Early Breast Cancer 2023" (2023), Annals of Oncology

Singer has frequently published in the following venues:

  • Cancer Research
  • Geburtshilfe und Frauenheilkunde
  • Journal of Clinical Oncology
  • Annals of Oncology
  • Breast Care

The scientist collaborates regularly with a set of frequent co-authors including Michael Gnant, Daniel Egle, Richard Greil, Marija Balić, and Rupert Bartsch.

Best Publications

  • Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

    Karoline B. Kuchenbaecker;Karoline B. Kuchenbaecker;John L. Hopper;Daniel R. Barnes;Kelly-Anne Phillips

  • Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality

    Susan M. Domchek;Tara M. Friebel;Christian F. Singer;D. Gareth Evans

  • ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer†

    A. Gennari;F. André;C.H. Barrios;J. Cortés

  • A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

    Martin Filipits;Margaretha Rudas;Raimund Jakesz;Peter Dubsky

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation

    Amy P.M. Finch;Jan Lubinski;Pål Møller;Christian F. Singer

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo- controlled trial

    Michael Gnant;Georg Pfeiler;Peter C Dubsky;Michael Hubalek

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Predicting distant recurrence in receptor-positive breast cancer patients with limited clinicopathological risk: using the PAM50 Risk of Recurrence score in 1478 postmenopausal patients of the ABCSG-8 trial treated with adjuvant endocrine therapy alone

    M. Gnant;M. Filipits;R. Greil;H. Stoeger

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  • The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2− breast cancer patients

    P Dubsky;J C Brase;R Jakesz;M Rudas

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Haoyu Zhang;Haoyu Zhang;Thomas U. Ahearn;Julie Lecarpentier;Daniel Barnes

  • Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

    Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  • Triple-Modality Screening Trial for Familial Breast Cancer Underlines the Importance of Magnetic Resonance Imaging and Questions the Role of Mammography and Ultrasound Regardless of Patient Mutation Status, Age, and Breast Density

    Christopher C. Riedl;Nikolaus Luft;Clemens Bernhart;Michael Weber

  • Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers

    Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Lesley McGuffog;Daniel Barrowdale;Andrew Lee

  • The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers.

    J Iqbal;A Ragone;J Lubinski;H T Lynch

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

    Timothy R. Rebbeck;Tara M. Friebel;Eitan Friedman;Ute Hamann

Frequent Co-Authors

Irene L. Andrulis
Irene L. Andrulis University of Toronto
Susan L. Neuhausen
Susan L. Neuhausen City Of Hope National Medical Center
Antonis C. Antoniou
Antonis C. Antoniou University of Cambridge
Douglas F. Easton
Douglas F. Easton University of Cambridge
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Jan Lubinski
Jan Lubinski Pomeranian Medical University
Michael Gnant
Michael Gnant Medical University of Vienna
Anna Jakubowska
Anna Jakubowska Pomeranian Medical University
Beth Y. Karlan
Beth Y. Karlan University of California, Los Angeles

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