World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
33768
World Ranking
8035
National Ranking
3643

Research.com Recognitions

  • 1994 - Nobel Prize for their discovery of G-proteins and the role of these proteins in signal transduction in cells
  • 1987 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their discoveries regarding the proteins and mechanisms that mediate cellular responses to the binding of ligands to cell surface receptors.
  • 1987 - Member of the National Academy of Sciences
  • 1984 - Canada Gairdner International Award

Overview

Martin Rodbell was affiliated with the National Institutes of Health in the United States. Their scientific work focused primarily on the discovery and understanding of cellular signal transduction mechanisms involving G-proteins.

Throughout their career, Martin Rodbell received several notable awards recognizing their contributions to molecular biology and biochemistry. In 1994, they were awarded the Nobel Prize for their discovery of G-proteins and the role of these proteins in signal transduction in cells.

Prior to this, in 1987, they were elected as a Member of the National Academy of Sciences. In the same year, Rodbell also received the Richard Lounsbery Award jointly given by the National Academy of Sciences and the French Academy of Sciences for discoveries related to the proteins and mechanisms mediating cellular responses to ligands binding to cell surface receptors.

In 1984, the Canada Gairdner International Award was granted to them, which recognizes significant contributions to medical science.

While their published works and frequent collaborators are not detailed here, the awards and affiliation reflect a research focus within cellular biology and biochemistry, especially related to signaling pathways inside the cell. Their work laid foundational understanding for how cells interpret external signals through G-proteins, which has widespread implications in many biological processes and medical research.

Best Publications

  • A Highly Sensitive Adenylate Cyclase Assay

    Yoram Salomon;Constantine Londos;Martin Rodbell

  • METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.

    Martin Rodbell

  • The role of hormone receptors and GTP-regulatory proteins in membrane transduction

    Martin Rodbell

  • The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver V. AN OBLIGATORY ROLE OF GUANYL NUCLEOTIDES IN GLUCAGON ACTION

    Martin Rodbell;Lutz Birnbaumer;Stephen L. Pohl;Hendrik Michiel Jan Krans

  • The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver I. PROPERTIES

    Stephen L. Pohl;Lutz Birnbaumer;Martin Rodbell

  • The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. VI. Evidence for a role of membrane lipids.

    Stephen L. Pohl;H. Michiel J. Krans;Vladimir Kozyreff;Lutz Birnbaumer

  • The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon.

    M Rodbell;H M Krans;S L Pohl;L Birnbaumer

  • Adenyl cyclase in fat cells. II. Hormone receptors.

    Lutz Birnbaumer;Martin Rodbell

  • Adenyl Cyclase in Fat Cells I. PROPERTIES AND THE EFFECTS OF ADRENOCORTICOTROPIN AND FLUORIDE

    Lutz Birnbaumer;Stephen L. Pohl;Martin Rodbell

  • The Glucagon-Sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver: III. Binding of Glucagon: Method of Assay and Specificity

    Martin Rodbell;Hendrik Michiel Jan Krans;Stephen L. Pohl;Lutz Birnbaumer

  • Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis

    Constantine Londos;Dermot M. F. Cooper;Werner Schlegel;Martin Rodbell

  • Metabolism of isolated fat cells. II. The similar effects of phospholipase C (Clostridium perfringens alpha toxin) and of insulin on glucose and amino acid metabolism.

    Martin Rodbell

  • LOCALIZATION OF LIPOPROTEIN LIPASE IN FAT CELLS OF RAT ADIPOSE TISSUE

    Martin Rodbell

  • Metabolism of Isolated Fat Cells V. PREPARATION OF "GHOSTS" AND THEIR PROPERTIES; ADENYL CYCLASE AND OTHER ENZYMES

    Martin Rodbell

  • Structure-function relationships in glucagon: properties of highly purified des-His-1-, monoiodo-, and (des-Asn-28, Thr-29)(homoserine lactone-27)-glucagon.

    Michael C. Lin;David E. Wright;Victor J. Hruby;Martin Rodbell

  • Evidence for interdependent action of glucagon and nucleotides on the hepatic adenylate cyclase system.

    Martin Rodbell;Michael C. Lin;Yoram Salomon

  • 5′-Guanylylimidodiphosphate, A Potent Activator of Adenylate Cyclase Systems in Eukaryotic Cells

    Constantine Londos;Yoram Salomon;Michael C. Lin;James P. Harwood

  • Adenyl Cyclase in Fat Cells III. STIMULATION BY SECRETIN AND THE EFFECTS OF TRYPSIN ON THE RECEPTORS FOR LIPOLYTIC HORMONES

    Martin Rodbell;Lutz Birnbaumer;Stephen L. Pohl

  • Metabolism of Isolated Fat Cells: III. THE SIMILAR INHIBITORY ACTION OF PHOSPHOLIPASE C (CLOSTRIDIUM PERFRINGENS α TOXIN) AND OF INSULIN ON LIPOLYSIS STIMULATED BY LIPOLYTIC HORMONES AND THEOPHYLLINE

    Martin Rodbell;Ann B. Jones

  • The metabolism of isolated fat cells

    Martin Rodbell

Frequent Co-Authors

Lutz Birnbaumer
Lutz Birnbaumer National Institutes of Health
Constantine Londos
Constantine Londos National Institutes of Health
Dermot M. F. Cooper
Dermot M. F. Cooper University of Cambridge
Victor J. Hruby
Victor J. Hruby University of Arizona
Hirohei Yamamura
Hirohei Yamamura Kobe University
Samuel W. Cushman
Samuel W. Cushman National Institutes of Health
Werner Schlegel
Werner Schlegel University of Geneva
Jacques Hanoune
Jacques Hanoune Grenoble Alpes University
Gordon G. Hammes
Gordon G. Hammes Duke University
Ian A. Simpson
Ian A. Simpson Pennsylvania State University

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