D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 11,525 424 World Ranking 6065 National Ranking 107

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Internal medicine

His primary areas of study are Receptor, Internal medicine, Endocrinology, Cyclase and Biochemistry. His Receptor study integrates concerns from other disciplines, such as Acinar cell and Binding site. His research links Calcium with Endocrinology.

The various areas that Jean Christophe examines in his Cyclase study include Adrenergic beta-Antagonists, Secretin, Vasoactive intestinal peptide and Adenylate kinase. In Adenylate kinase, Jean Christophe works on issues like Cell surface receptor, which are connected to Signal transduction. As a member of one scientific family, Jean Christophe mostly works in the field of Biochemistry, focusing on Chromatography and, on occasion, Lipase, Polyacrylamide gel electrophoresis, Tryptophan and Membrane.

His most cited work include:

  • Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain (230 citations)
  • Type I receptors for PACAP (a neuropeptide even more important than VIP (204 citations)
  • Structural requirements for the occupancy of pituitary adenylate‐cyclase‐activating‐peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB‐OK‐1 cell membranes (194 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Endocrinology, Biochemistry, Receptor and Cyclase. His work in Internal medicine addresses subjects such as Amylase, which are connected to disciplines such as Lipase. His studies examine the connections between Endocrinology and genetics, as well as such issues in Vasoactive intestinal peptide, with regards to Guinea pig.

He has researched Receptor in several fields, including Molecular biology and Binding site. The concepts of his Cyclase study are interwoven with issues in Neuropeptide, Cholera toxin and Adenylate kinase. His studies in Adenylate kinase integrate themes in fields like GTP' and Peptide hormone.

He most often published in these fields:

  • Internal medicine (56.25%)
  • Endocrinology (55.58%)
  • Biochemistry (34.37%)

What were the highlights of his more recent work (between 1989-2008)?

  • Receptor (29.91%)
  • Biochemistry (34.37%)
  • Internal medicine (56.25%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Receptor, Biochemistry, Internal medicine, Endocrinology and Cyclase. Jean Christophe interconnects Molecular biology, Acinar cell and Binding site in the investigation of issues within Receptor. Much of his study explores Internal medicine relationship to Biological activity.

His research integrates issues of Gene expression and Glucagon-like peptide 1 receptor in his study of Endocrinology. His Cyclase research is multidisciplinary, incorporating elements of Neuropeptide, Vasoactive intestinal peptide and Adenylate kinase. His work in Adenylate kinase tackles topics such as Stimulation which are related to areas like Cell growth.

Between 1989 and 2008, his most popular works were:

  • Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain (230 citations)
  • Type I receptors for PACAP (a neuropeptide even more important than VIP (204 citations)
  • Structural requirements for the occupancy of pituitary adenylate‐cyclase‐activating‐peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB‐OK‐1 cell membranes (194 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Gene

Jean Christophe mainly focuses on Receptor, Adenylate kinase, Internal medicine, Endocrinology and Cyclase. His Receptor study introduces a deeper knowledge of Biochemistry. His work on Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor, Arc and Appetite as part of general Internal medicine research is often related to Hyperinsulinemia, thus linking different fields of science.

His Leptin and Amylin study in the realm of Endocrinology interacts with subjects such as Glucagon-like peptide-1. His Cyclase study combines topics in areas such as Neuropeptide, Peptide, Membrane and Peptide hormone. Pituitary gland and Somatotropic cell is closely connected to Cyclase activity in his research, which is encompassed under the umbrella topic of Pituitary adenylate cyclase-activating peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Binding of selective antagonists to four muscarinic receptors (M1 to M4) in rat forebrain

Magali Waelbroeck;Michèle Tastenoy;Jean Claude Camus;Jean Christophe.
Molecular Pharmacology (1990)

347 Citations

Type I receptors for PACAP (a neuropeptide even more important than VIP

Jean Christophe.
Biochimica et Biophysica Acta (1993)

311 Citations

Structural requirements for the occupancy of pituitary adenylate‐cyclase‐activating‐peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB‐OK‐1 cell membranes

Patrick Robberecht;Philippe Gourlet;Philippe De Neef;Marie‐Claire Woussen‐Colle.
FEBS Journal (1992)

297 Citations

Interaction of porcine vasoactive intestinal peptide with dispersed pancreatic acinar cells from the guinea pig. Binding of radioiodinated peptide.

J P Christophe;T P Conlon;J D Gardner.
Journal of Biological Chemistry (1976)

280 Citations

Interaction of growth hormone-releasing factor (GRF) and 14 GRF analogs with vasoactive intestinal peptide (VIP) receptors of rat pancreas. Discovery of (N-Ac-Tyr1,D-Phe2)-GRF(1-29)-NH2 as a VIP antagonist.

Magali Waelbroeck;Patrick Robberecht;David H. Coy;Jean-Claude Camus.
Endocrinology (1985)

218 Citations

Action of cholecystokinin, cholinergic agents, and A-23187 on accumulation of guanosine 3':5'-monophosphate in dispersed guinea pig pancreatic acinar cells.

J P Christophe;E K Frandsen;T P Conlon;G Krishna.
Journal of Biological Chemistry (1976)

187 Citations

Pancreatic tumoral cell line AR42J: an amphicrine model.

Jean Christophe.
American Journal of Physiology-gastrointestinal and Liver Physiology (1994)

177 Citations

Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR 4-2J

Louis Buscail;Philippe Gourlet;Annick Cauvin;Philippe De Neef.
FEBS Letters (1990)

174 Citations

The novel VIP-like hypothalamic polypeptide PACAP interacts with high affinity receptors in the human neuroblastoma cell line NB-OK

Annick Cauvin;Louis Buscail;Philippe Gourlet;Philippe De Neef.
Peptides (1990)

166 Citations

Characterization of VIP-sensitive adenylate cyclase in guinea pig brain

M. Deschodt-Lanckman;P. Robberecht;J. Christophe.
FEBS Letters (1977)

162 Citations

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