World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
44
Citations
7777
World Ranking
16774
National Ranking
4156

Research.com Recognitions

  • 2014 - Fellow of Alfred P. Sloan Foundation

Overview

Matthew F. Bush is affiliated with the University of Washington in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and chemistry. A significant focus of their work lies in molecular biology and spectroscopy, supported by extensive publications in these subfields.

The main fields of study covered by their research include:

  • Biochemistry, Genetics and Molecular Biology
  • Chemistry

Their subfields of study further detail this concentration as:

  • Molecular Biology
  • Spectroscopy
  • Pharmacology
  • Computational Mechanics
  • Biomedical Engineering

The primary topics addressed within their work are:

  • Mass Spectrometry Techniques and Applications
  • Protein Structure and Dynamics
  • Analytical Chemistry and Chromatography
  • Heat shock proteins research
  • Ion-surface interactions and analysis
  • Advanced Proteomics Techniques and Applications
  • Microfluidic and Capillary Electrophoresis Applications

Matthew F. Bush has published multiple significant papers in recent years. Key publications include:

  • "FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster," 2020, Molecular Cell
  • "An artificial intelligence accelerated virtual screening platform for drug discovery," 2024, Nature Communications
  • "Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin," 2023, Proceedings of the National Academy of Sciences
  • "Effects of charge on protein ion structure: Lessons from cation-to-anion, proton-transfer reactions," 2023, Mass Spectrometry Reviews
  • "Activation mechanism of Small Heat Shock Protein HSPB5 revealed by disease-associated mutants," 2022, bioRxiv (Cold Spring Harbor Laboratory)

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Society for Mass Spectrometry
  • Analytical Chemistry
  • Proceedings of the National Academy of Sciences
  • Molecular Cell

Frequent co-authors collaborating on multiple projects are:

  • Benjamin P. Zercher
  • Lindsey D. Ulmer
  • Miklós Guttman
  • Rachel E. Klevit
  • Christopher N. Woods

In 2014, Matthew F. Bush was recognized as a Fellow of the Alfred P. Sloan Foundation. This award is an indicator of distinction within research communities.

Best Publications

  • Collision Cross Sections of Proteins and Their Complexes: A Calibration Framework and Database for Gas-Phase Structural Biology

    Matthew F. Bush;Zoe Hall;Kevin Giles;John Hoyes

  • Recommendations for reporting ion mobility Mass Spectrometry measurements

    Valérie Gabelica;Alexandre A. Shvartsburg;Carlos Afonso;Perdita Barran

  • Structural Characterization of Drug-like Compounds by Ion Mobility Mass Spectrometry: Comparison of Theoretical and Experimentally Derived Nitrogen Collision Cross Sections

    Iain Campuzano;Matthew F. Bush;Carol V. Robinson;Claire Beaumont

  • Ion mobility mass spectrometry of peptide ions: effects of drift gas and calibration strategies.

    Matthew F. Bush;Iain D. G. Campuzano;Carol V. Robinson

  • Charge-State Dependent Compaction and Dissociation of Protein Complexes: Insights from Ion Mobility and Molecular Dynamics

    Zoe Hall;Argyris Politis;Matthew F. Bush;Lorna J. Smith

  • SCF FBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket

    Weiman Xing;Luca Busino;Thomas R. Hinds;Samuel T. Marionni

  • Infrared spectroscopy of cationized arginine in the gas phase: direct evidence for the transition from nonzwitterionic to zwitterionic structure.

    Matthew F. Bush;Jeremy T. O'Brien;James S. Prell;Richard J. Saykally

  • Infrared spectroscopy of hydrated amino acids in the gas phase: protonated and lithiated valine.

    Anthi Kamariotis;Oleg V. Boyarkin;Sébastien R. Mercier;Rainer D. Beck

  • Infrared spectroscopy of arginine cation complexes: direct observation of gas-phase zwitterions.

    Matthew W. Forbes;Matthew F. Bush;Nick C. Polfer;Jos Oomens

  • Effects of alkaline earth metal ion complexation on amino acid zwitterion stability: results from infrared action spectroscopy.

    Matthew F. Bush;Jos Oomens;Richard J. Saykally;Evan R. Williams

  • Traveling-wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross-sections of human insulin oligomers.

    Rune Salbo;Rune Salbo;Matthew F Bush;Helle Naver;Iain Campuzano

  • FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.

    Hui Wang;Hui Shi;Malini Rajan;Elizabeth R. Canarie

  • Sulfate ion patterns water at long distance.

    Jeremy T O'Brien;James S Prell;Matthew F Bush;Evan R Williams

  • Absolute standard hydrogen electrode potential measured by reduction of aqueous nanodrops in the gas phase.

    William A. Donald;Ryan D. Leib;Jeremy T. O'Brien;Matthew F. Bush

  • Defining the mechanism of polymerization in the serpinopathies

    Ugo I. Ekeowa;Joanna Freeke;Elena Miranda;Bibek Gooptu

  • Large-Scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry.

    Kelly M. Hines;Dylan H. Ross;Kimberly L. Davidson;Matthew F. Bush

  • Ion mobility mass spectrometry of peptide, protein, and protein complex ions using a radio-frequency confining drift cell

    Samuel J. Allen;Kevin Giles;Tony Gilbert;Matthew F. Bush

  • One water molecule stabilizes the cationized arginine zwitterion.

    Matthew F. Bush;James S. Prell;Richard J. Saykally;Evan R. Williams

  • Infrared Spectroscopy of Cationized Lysine and ε-N-methyllysine in the Gas Phase: Effects of Alkali-Metal Ion Size and Proton Affinity on Zwitterion Stability

    Matthew F. Bush;Matthew W. Forbes;Rebecca A. Jockusch;Jos Oomens

  • Infrared action spectra of Ca2+(H2O)(11-69) exhibit spectral signatures for condensed-phase structures with increasing cluster size.

    Matthew F. Bush;Richard J. Saykally;Evan R. Williams

Frequent Co-Authors

Evan R. Williams
Evan R. Williams University of California, Berkeley
Richard J. Saykally
Richard J. Saykally University of California, Berkeley
Carol V. Robinson
Carol V. Robinson University of Oxford
František Tureček
František Tureček University of Washington
Jos Oomens
Jos Oomens Radboud University
Ning Zheng
Ning Zheng University of Washington
Justin L. P. Benesch
Justin L. P. Benesch University of Oxford
Alexandre A. Shvartsburg
Alexandre A. Shvartsburg Wichita State University
Michele Pagano
Michele Pagano New York University
Brandon T. Ruotolo
Brandon T. Ruotolo University of Michigan–Ann Arbor

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