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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
9853
World Ranking
15158
National Ranking
1195

Overview

Edel A. O'Toole is affiliated with Queen Mary University of London in the United Kingdom. Their research spans across multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with specific subfields focusing on Cell Biology, Dermatology, Molecular Biology, Genetics, and Immunology.

The scientist's work extensively covers topics related to Skin and Cellular Biology Research, Dermatology and Skin Diseases, Dermatological and Skeletal Disorders, Allergic Rhinitis and Sensitization, Nail Diseases and Treatments, Plant Reproductive Biology, and Contact Dermatitis and Allergies.

Recent notable publications by Edel A. O'Toole include:

  • "Developmental cell programs are co-opted in inflammatory skin disease," 2021, Science
  • "3D model of harlequin ichthyosis reveals inflammatory therapeutic targets," 2020, Journal of Clinical Investigation
  • "A prenatal skin atlas reveals immune regulation of human skin morphogenesis," 2024, Nature
  • "Tape strips in dermatology research*," 2020, British Journal of Dermatology
  • "Distinctive clinical and histological characteristics of atrophic and hypertrophic facial photoageing," 2020, Journal of the European Academy of Dermatology and Venereology

They have frequently collaborated with other researchers including Matthew Caley, Bjorn Thomas, Janice Schwartz, Eli Sprecher, and Aaron Hughes.

Edel A. O'Toole's publications appear most frequently in the following venues:

  • British Journal of Dermatology (51 publications)
  • Journal of Investigative Dermatology (22 publications)
  • Clinical and Experimental Dermatology (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Journal of the American Academy of Dermatology (3 publications)

Best Publications

  • Metalloproteinases and Wound Healing.

    Matthew P. Caley;Vera L.C. Martins;Edel A. O'Toole

  • Developmental cell programs are co-opted in inflammatory skin disease

    Gary Reynolds;Peter Vegh;James Fletcher;Elizabeth F. M. Poyner

  • Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.

    David P. Kelsell;Elizabeth E. Norgett;Harriet Unsworth;Muy Teck Teh

  • Inflammatory Skin and Bowel Disease Linked to ADAM17 Deletion

    Diana C. Blaydon;Paolo Biancheri;Wei Li Di;Vincent Plagnol

  • Extracellular matrix and keratinocyte migration.

    E. A. O'Toole

  • Matrix metalloproteinases and epidermal wound repair

    Vera L. Martins;Matthew Caley;Edel A. O’Toole

  • Clinical and pathological features of pachyonychia congenita.

    Sancy A. Leachman;Roger L. Kaspar;Philip Fleckman;Scott R. Florell

  • Interactions of the Amino-terminal Noncollagenous (NC1) Domain of Type VII Collagen with Extracellular Matrix Components A POTENTIAL ROLE IN EPIDERMAL-DERMAL ADHERENCE IN HUMAN SKIN

    Mei Chen;M. Peter Marinkovich;Arthur Veis;Xiaoyan Cai

  • Harlequin Ichthyosis: A Review of Clinical and Molecular Findings in 45 Cases

    Shefali Rajpopat;Celia Moss;Jemima Mellerio;Anders Vahlquist

  • The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

    Diana C Blaydon;Yoshiyuki Ishii;Edel A O'Toole;Harriet C Unsworth

  • Development of an ELISA for Rapid Detection of Anti-Type VII Collagen Autoantibodies in Epidermolysis Bullosa Acquisita

    Mei Chen;Lawrence S. Chan;Xiaoyan Cai;Edel A. O'Toole

  • Necrobiosis lipoidica: only a minority of patients have diabetes mellitus.

    E A O'Toole;U Kennedy;J J Nolan;M M Young

  • ENHANCED MODULATION OF KERATINOCYTE MOTILITY BY TRANSFORMING GROWTH FACTOR-ALPHA (TGF-ALPHA ) RELATIVE TO EPIDERMAL GROWTH FACTOR (EGF)

    Donald Cha;Patricia O'Brien;Edel A. O'Toole;David T. Woodley

  • Hypoxia increases human keratinocyte motility on connective tissue.

    E A O'Toole;M P Marinkovich;C L Peavey;M R Amieva

  • Laminin-5 inhibits human keratinocyte migration

    E A O'Toole;M P Marinkovich;M P Marinkovich;W K Hoeffler;W K Hoeffler;H Furthmayr

  • NC1 domain of type VII collagen binds to the β3 chain of laminin 5 via a unique subdomain within the fibronectin-like repeats

    Mei Chen;Jonathan C.R. Jones;Edel A. O'Toole;Yu-Yu Li

  • Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen

    Vera L. Martins;Jashmin J. Vyas;Mei Chen;Karin Purdie

  • Extracellular Matrix-Associated Serine Protease Inhibitors (Mr33,000, 31,000, and 27,000) Are Single-Gene Products with Differential Glycosylation: cDNA Cloning of the 33-kDa Inhibitor Reveals Its Identity to Tissue Factor Pathway Inhibitor-2

    C.N. Rao;Prasad Reddy;Yueying Liu;Edel O'toole

  • Hydrogen Peroxide Inhibits Human Keratinocyte Migration

    Edel A. O'toole;Mimi Goel;David T. Woodley

  • The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen.

    Mei Chen;Edel A O'Toole;Jigisha Sanghavi;Nasir Mahmud

Frequent Co-Authors

David P. Kelsell
David P. Kelsell Queen Mary University of London
David T. Woodley
David T. Woodley University of Southern California
Mei Chen
Mei Chen University of Southern California
John A. McGrath
John A. McGrath King's College London
Frances J.D. Smith
Frances J.D. Smith University of Dundee
Irene M. Leigh
Irene M. Leigh University of Dundee
Charles A. Mein
Charles A. Mein Queen Mary University of London
Judith Breuer
Judith Breuer University College London
Michael A. Simpson
Michael A. Simpson King's College London
W.H. Irwin McLean
W.H. Irwin McLean University of Dundee

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