What is she best known for?
The fields of study she is best known for:
- Gene
- Cancer
- Internal medicine
Edel A. O'Toole mostly deals with Laminin, Cell biology, Keratinocyte, Pathology and Fibronectin.
Edel A. O'Toole focuses mostly in the field of Laminin, narrowing it down to topics relating to Immunology and, in certain cases, Hemidesmosome.
Her Cell biology study incorporates themes from Wound healing and Growth factor, TGF alpha.
Her Keratinocyte research incorporates themes from Matrix metalloproteinase, Metalloproteinase, Transforming growth factor, Dermis and Human skin.
Her Pathology research integrates issues from Peripheral blood mononuclear cell, Myocarditis and Desmoglein-2.
Her research investigates the link between Fibronectin and topics such as Integrin that cross with problems in Signal transduction and Keratinocyte migration.
Her most cited work include:
- Metalloproteinases and Wound Healing. (274 citations)
- Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis. (256 citations)
- Inflammatory Skin and Bowel Disease Linked to ADAM17 Deletion (218 citations)
What are the main themes of her work throughout her whole career to date?
Edel A. O'Toole mainly investigates Dermatology, Pathology, Cell biology, Keratinocyte and Cancer research.
Her work in Dermatology covers topics such as Pachyonychia congenita which are related to areas like Keratoderma.
She interconnects Phenotype and Ichthyosis in the investigation of issues within Pathology.
Her work deals with themes such as Epidermal growth factor and Desmoglein 3, which intersect with Cell biology.
The various areas that Edel A. O'Toole examines in her Keratinocyte study include Wound healing, Immunology and Molecular biology.
Her Molecular biology study integrates concerns from other disciplines, such as Mutation, Fibronectin and Recombinant DNA.
She most often published in these fields:
- Dermatology (20.39%)
- Pathology (18.93%)
- Cell biology (17.48%)
What were the highlights of her more recent work (between 2015-2021)?
- Dermatology (20.39%)
- Genetics (12.14%)
- Cancer research (13.11%)
In recent papers she was focusing on the following fields of study:
Her scientific interests lie mostly in Dermatology, Genetics, Cancer research, Cell biology and Pathology.
While the research belongs to areas of Dermatology, she spends her time largely on the problem of Pachyonychia congenita, intersecting her research to questions surrounding Plantar pain and Genetic diagnosis.
The concepts of her Cancer research study are interwoven with issues in Immunohistochemistry, Macrophage recruitment, Carcinogenesis, Laminin and Periostin.
Her research integrates issues of Type VII collagen and HIF1A in her study of Cell biology.
Edel A. O'Toole has researched Pathology in several fields, including Phenotype, Haploinsufficiency and Desmoplakin.
In her work, Keratinocyte is strongly intertwined with Epidermal growth factor, which is a subfield of Signalling.
Between 2015 and 2021, her most popular works were:
- Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC (37 citations)
- Management of congenital ichthyoses: European guidelines of care, part one (24 citations)
- Epidermal grafting for wound healing: a review on the harvesting systems, the ultrastructure of the graft and the mechanism of wound healing. (16 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
Her scientific interests lie mostly in Dermatology, Palmoplantar keratoderma, Cancer research, Keratoderma and Genetics.
In general Dermatology, her work in Ichthyosis is often linked to In patient linking many areas of study.
Her Cancer research research includes elements of Immunohistochemistry, Small hairpin RNA, microRNA and EZH2.
Edel A. O'Toole combines subjects such as DNA Mutational Analysis, Missense mutation, Mutation and Frameshift mutation with her study of Keratoderma.
Her study in the fields of Genotype and Gene under the domain of Genetics overlaps with other disciplines such as Christian ministry.
Her Gene mutation research incorporates elements of ABCA12 and Congenital ichthyosis.
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